Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026850 (muscular dystrophy)
 5,870 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Report of an International Symposion (Febr. 15, 1975, Munich). Human growth hormone (HGH) acts on proliferation of cartilage, the basal process of growth, by the way of somatomedine and changes in protein metabolism. Growth can be enhanced in hypopituitary dwardism and with higher dosage in other forms of failure to thrive. HGH also seems to have a beneficial effect in patients with muscular dystrophy as shown in a preliminary report but not in thrombocytopenia. First observations on patients with osteogenesis imperfecta and on patients with non healing fractures of the long bones (pseudarthroses) have shown significant improvement. Of importance are the reports on stopping severe gastric hemorrhage in patients with stress ulcera.
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PMID:[Proceedings: The clinical effects of human growth hormone. Report on an international symposium of the German Kabi Corp. on February 15, 1975 in Munich]. 121 33

We report a case of Castleman's disease in a 48-year-old male who complained of a rapidly enlarging mass on the neck. Thrombocytopenia and the facio-scapulo-humeral type of progressive muscular dystrophy were also present. The mass was extirpated, and histopathological examinations showed the hyaline-vascular type of Castleman's disease. Following resection, thrombocytopenia was ameliorated. Immunological study with flow cytometric analysis was made to clarify the nature of his mass. With reference to recent literature we suggest that the hyaline-vascular type of Castleman's disease may be an atypical hyperplasia of the lymphoid tissue.
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PMID:Immunologic study of the hyaline-vascular type of Castleman's disease. A case study. 847 May 23