Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026850 (muscular dystrophy)
 5,870 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper presents the development of a new active assistive eating device, which aims to stabilize the movements of people living with movement disorders, such as spasticity and ataxia. Many people living with upper-body incapacities are unable to eat on their own, due to movement disorders (ex. tremors, spastic motions, lack of muscular tone), resulting from various ailments like Cerebral palsy, Parkinson's disease, Dystonia, Multiple sclerosis, strokes, and Muscular dystrophy). Our past work focused on the development of a purely mechanical device, which involved damping of the system via passive mechanical dampers. This paper extends said work by using active stabilization of user movements. The active assistance enables the design of intelligent algorithms that can assist human movements more efficiently. This active version has the benefits of being easily adjustable; the level of damping can be adjusted in real-time, depending on the user movement; different control modes are offered, and the guiding of user movements is also allowed. Firstly, the mechanical design of the device is presented, followed by the damping arrangement, the electronic design, the control algorithms and finally, the preliminary experiments are mentioned.
 ...
PMID:Preliminary Design of an Active Stabilization Assistive Eating Device for People Living with Movement Disorders. 3137 33

Objective: Aging with physical disability disrupts one's ability to achieve valued goals due to changes in symptoms and function. It is unclear how to cope optimally in this context. This study examined whether two possible strategies-tenacious goal pursuit (TGP) and flexible goal adjustment (FGA)-were associated with reduced pain interference and depressive symptoms and greater well-being, and protected against pain intensity, and FGA was more protective with increasing age and worse physical function. Method: Middle-aged adults with muscular dystrophy, multiple sclerosis, post-polio syndrome, or spinal cord injury (N = 874; MAGE = 58.3 years, range = 46-68; MDISEASEDURATION = 26.2 years, range = 2-67) completed two questionnaires, a year apart. Results: TGP and FGA use was associated with greater well-being. FGA use predicted decreased depressive symptoms. Concurrent use of both predicted decreased pain interference. Discussion: Adults with disability employ a variety of goal management strategies. Findings support TGP and FGA as potential intervention targets for healthy aging with disabilities.
 ...
PMID:Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability. 3171 16

Parkinson's disease (PD) is a complex condition with a wide range of symptoms, like impaired movement, tremors, apathy and depression, and many other symptoms. The disease results from degeneration of dopaminergic neural cells. No cure at present but symptomatic some palliative treatments are available to slow down the disease progression. According to the Parkinson's Foundation every year in U.S., approximately 60,000 Americans diagnosed with PD. Nearly one million will be living with PD in the U.S. by 2020, which is more than the combined number of people diagnosed with multiple sclerosis, muscular dystrophy and Amyotrophic Lateral Sclerosis (ALS). There is no diagnostic test for PD, yet, but this article will review all kinds symptomatic and disease-modifying therapy.
 ...
PMID:Possible therapies of Parkinson's disease: A review. 3224 40

Parkinson's disease (PD) is a complex condition with a wide range of symptoms, like impaired movement, tremors, apathy and depression, and many other symptoms. The disease results from degeneration of dopaminergic neural cells. No cure at present but symptomatic some palliative treatments are available to slow down the disease progression. According to the Parkinson's Foundation every year in U.S., approximately 60,000 Americans diagnosed with PD. Nearly one million will be living with PD in the U.S. by 2020, which is more than the combined number of people diagnosed with multiple sclerosis, muscular dystrophy and Amyotrophic Lateral Sclerosis (ALS). There is no diagnostic test for PD, yet, but this article will review all kinds symptomatic and disease-modifying therapy.
 ...
PMID:A review of possible therapies for Parkinson's disease. 3227 16


<< Previous 1 2 3 4