Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026838 (
spasticity
)
6,471
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
spastin
0.003
SPG3A
0.002
SPG11
0.001
SPAST
0.001
SPG3
0.001
fatty aldehyde dehydrogenase
0.001
SPG10
0.001
SPG6
0.001
ATL1
0.001
SACS
0.001
REEP1
0.001
atlastin-1
0.001
SPG7
0.001
ALDH3A2
0.001
SPG8
0.001
reticulon 2
0.000
NIPA1
0.000
ARSACS
0.000
DDHD2
0.000
FSP2
0.000
DARS2
0.000
KIAA0415
0.000
Cx47
0.000
SPG15
0.000
DDHD1
0.000
KIF5A
0.000
ZFYVE27
0.000
KIAA1840
0.000
ZFYVE26
0.000
SPG3A protein
0.000
B3GalNAc-T2
0.000
Phospholipase DDHD2
0.000
SPG20
0.000
MLC1
0.000
CYP2U1
0.000
SPG42
0.000
SPG2
0.000
OPA3
0.000
KIF1A
0.000
ERLIN2
0.000
spartin
0.000
GBA2
0.000
LYR motif-containing protein 7
0.000
NIPA1 protein
0.000
Kinesin family member 5A
0.000
Rab40A
0.000
GDAP2
0.000
EIF2B5
0.000
Troyer syndrome
0.000
C19orf12
0.000
TIZ
0.000
SCI
0.000
L1 cell adhesion molecule
0.000
PLA2G6
0.000
RTN2
0.000
CYP7B1
0.000
C19orf2
0.000
AP4B1
0.000
KCC2
0.000
Silver syndrome
0.000
WDR45
0.000
KIAA0196
0.000
L1CAM
0.000
ISSX
0.000
X-linked
0.000
MRI
0.000
RAB9B
0.000
FLJ10737
0.000
TSEN34
0.000
fatty acid hydroxylase
0.000
EIF2B4
0.000
EXOSC3
0.000
PLP1
0.000
PANK2
0.000
ZC4H2
0.000
UBAP1
0.000
proteolipid protein 1
0.000
ARD1A
0.000
KIF1C
0.000
DNAJC11
0.000
more...
Disease
cerebral palsy
0.014
Hereditary spastic paraplegia
0.010
spastic paraplegia
0.006
SPG4
0.004
spastic diplegia
0.002
SPG11
0.001
multiple sclerosis
0.001
primary lateral sclerosis
0.001
SACS
0.001
SPG6
0.001
SPG10
0.001
tetraplegia
0.001
SPG8
0.001
stroke
0.001
choreoathetosis
0.001
SPG30
0.001
SPG7
0.001
SPG31
0.001
hyperargininemia
0.001
SPG12
0.001
SPG28
0.000
Pelizaeus-Merzbacher
0.000
developmental delay
0.000
hemiparesis
0.000
SPG1
0.000
Spastic cerebral palsy
0.000
leukodystrophy
0.000
mental retardation
0.000
mental retardation
0.000
paraplegia
0.000
Fitzsimmons syndrome
0.000
leukoencephalopathy
0.000
optic atrophy
0.000
myelopathy
0.000
diplegia
0.000
Miles-Carpenter syndrome
0.000
SPG13
0.000
SPG9
0.000
SPG15
0.000
Lesch-Nyhan syndrome
0.000
OPA3
0.000
SPG33
0.000
SPG20
0.000
Muscle tone abnormalities
0.000
IAHSP
0.000
Gaze palsy
0.000
Exacerbation of multiple sclerosis
0.000
Pectoralis minor syndrome
0.000
Spastic quadriplegic cerebral palsy
0.000
SPG19
0.000
Spastic ataxia
0.000
SPG2
0.000
macrocephaly
0.000
SPG21
0.000
amyotrophic lateral sclerosis
0.000
Cannabis
0.000
Pure hereditary spastic paraplegia
0.000
nystagmus
0.000
neurogenic bladder
0.000
decubitus
0.000
ichthyosis
0.000
X-linked hydrocephalus
0.000
epilepsy
0.000
3-Methylglutaconic aciduria
0.000
Pelizaeus-Merzbacher disease
0.000
SPG14
0.000
SPG27
0.000
Post-thoracotomy pain syndrome
0.000
ENFL2
0.000
SPG24
0.000
Upper motor neuron disease
0.000
Shoulder-hand syndrome
0.000
motor neuron disease
0.000
triplegia
0.000
INAD
0.000
Partington syndrome
0.000
Alexander disease
0.000
severe mental retardation
0.000
ichthyosis
0.000
movement disorder
0.000
more...
Symptom
spasticity
1.000
hypertonia
0.006
clonus
0.003
dystonia
0.003
ataxia
0.002
weakness
0.002
athetosis
0.002
Spastic
0.002
hemiplegia
0.001
paraparesis
0.001
hypotonia
0.001
dysarthria
0.001
cerebellar ataxia
0.001
pain
0.000
spasm
0.000
paresis
0.000
blepharospasm
0.000
muscle stiffness
0.000
Spastic paraparesis
0.000
seizures
0.000
Spastic hemiplegia
0.000
Clasp-knife phenomenon
0.000
Abnormal muscle tone
0.000
Decerebrate posture
0.000
tremor
0.000
Pyramidal signs
0.000
myoclonus
0.000
abnormal gait
0.000
abnormal reflex
0.000
fatigue
0.000
drooling
0.000
hemiathetosis
0.000
Flaccidity
0.000
joint stiffness
0.000
Central pain
0.000
ataxic gait
0.000
Ankle stiffness
0.000
chorea
0.000
shoulder pain
0.000
intention tremor
0.000
muscle rigidity
0.000
Truncal ataxia
0.000
Other pain
0.000
clumsiness
0.000
torticollis
0.000
Hyperekplexia
0.000
functional recovery
0.000
Opisthotonus
0.000
bradykinesia
0.000
Spasmodic dysphonia
0.000
Neurogenic pain
0.000
fasciculation
0.000
disturbed speech
0.000
sleepiness
0.000
muscle cramps
0.000
dysesthesia
0.000
Lhermitte's sign
0.000
ophthalmoplegia
0.000
hemihypesthesia
0.000
constipation
0.000
Procedural pain
0.000
paresthesia
0.000
incoordination
0.000
asthenia
0.000
Central post-stroke pain
0.000
numbness
0.000
cancer pain
0.000
feeling sick
0.000
PAIN
0.000
Peripheral neuropathic pain
0.000
Opposition
0.000
abdominal rigidity
0.000
headache
0.000
loss of balance
0.000
Motor dysfunction
0.000
dizziness
0.000
nausea and vomiting
0.000
musculoskeletal impairment
0.000
personality change
0.000
neurological disability
0.000
more...
Drug
Lioresal
0.001
Botox
0.001
Dantrium
0.000
Dantrolene sodium
0.000
Sirdalud
0.000
BOTOX
0.000
Eperisone hydrochloride
0.000
Myobloc
0.000
Tizanidine hydrochloride
0.000
Tezampanel
0.000
Nabilone
0.000
BoNT/A
0.000
Tolperisone hydrochloride
0.000
9-THC
0.000
Orphenadrine citrate
0.000
Iophendylate
0.000
Afloqualone
0.000
Posture
0.000
Progabide
0.000
Oleic Acid
0.000
Rilutek
0.000
p-Chlorophenyl
0.000
CSF
0.000
Foscavir
0.000
Clonidine
0.000
Dibenzyline
0.000
Ditropan
0.000
Gabapentin
0.000
Diphenhydramine
0.000
Interferon beta
0.000
Buscopan
0.000
Bactrim
0.000
Ziconotide
0.000
Modafinil
0.000
Miglustat
0.000
Sodium benzoate
0.000
Pantopaque
0.000
Madopar
0.000
Zmax
0.000
CVA
0.000
Idebenone
0.000
NAH
0.000
Carbidopa
0.000
Trimethoprim-sulfamethoxazole
0.000
Opium
0.000
Prograf
0.000
Dihydroergotamine
0.000
Novantrone
0.000
Phenytoin
0.000
TMS
0.000
Isoptin
0.000
Metrizamide
0.000
EMB
0.000
Ketorolac
0.000
Duloxetine
0.000
Rimonabant
0.000
Coumadin
0.000
Xanthium
0.000
MRC
0.000
Natalizumab
0.000
PCP
0.000
Rolipram
0.000
PFT
0.000
EHDP
0.000
Glutamic acid
0.000
Sinemet
0.000
Orphan
0.000
Azithromycin
0.000
ABC
0.000
Domperidone
0.000
Bayer
0.000
Camp
0.000
Ganciclovir
0.000
Bupivacaine
0.000
Norplant
0.000
Amoxicillin
0.000
Frontal
0.000
Photofrin
0.000
THA
0.000
DFP
0.000
more...
Enzyme
botulinum neurotoxin
0.001
EC 1.2.1.48
0.000
CYP7B1
0.000
calpain B
0.000
plasmanylethanolamine desaturase
0.000
methylglutaconyl coenzyme A hydratase
0.000
pterin-4alpha-carbinolamine dehydratase
0.000
aspartyl-tRNA synthetase
0.000
5,10-methenyltetrahydrofolate synthetase
0.000
alkylglycerol monooxygenase
0.000
galactocerebrosidase
0.000
pantothenate kinase
0.000
fatty acyl-CoA reductase
0.000
hypoxanthine-guanine phosphoribosyltransferase
0.000
aspartoacylase
0.000
CYP27A1
0.000
glutaryl-CoA dehydrogenase
0.000
arginase
0.000
methionyl-tRNA formyltransferase
0.000
m-AAA protease
0.000
Lod
0.000
arylsulfatase A
0.000
SCS
0.000
dihydroxyacetone phosphate acyltransferase
0.000
splicing endonuclease
0.000
tetanus neurotoxin
0.000
branching enzyme
0.000
DSR
0.000
asparagine synthetase
0.000
phosphoserine aminotransferase
0.000
HOA
0.000
succinic semialdehyde dehydrogenase
0.000
guanidinoacetate methyltransferase
0.000
arginyl-tRNA synthetase
0.000
hexosaminidase
0.000
FADS
0.000
biotinidase
0.000
TSR
0.000
sepiapterin reductase
0.000
glutamyl-tRNA synthetase
0.000
sulfatase
0.000
alanyl-tRNA synthetase
0.000
4-hydroxyphenylpyruvate dioxygenase
0.000
complex I
0.000
lysyl hydroxylase
0.000
CCS
0.000
neuropathy target esterase
0.000
GTP cyclohydrolase I
0.000
PDH
0.000
mu-calpain
0.000
adenine phosphoribosyltransferase
0.000
phosphoglycerate dehydrogenase
0.000
glycerol kinase
0.000
alpha-L-fucosidase
0.000
dopamine beta-hydroxylase
0.000
glucocerebrosidase
0.000
PME
0.000
methylmalonyl-CoA mutase
0.000
phospholipase A1
0.000
dihydropteridine reductase
0.000
HCS
0.000
argininosuccinate lyase
0.000
PCP
0.000
carnitine acetyltransferase
0.000
ornithine transcarbamylase
0.000
sulfite oxidase
0.000
sulfite oxidase
0.000
alpha-L-fucosidase
0.000
Hageman factor
0.000
alpha-L-fucosidase
0.000
methylenetetrahydrofolate reductase
0.000
methylenetetrahydrofolate reductase
0.000
ATPase
0.000
CNPase
0.000
neutral sphingomyelinase
0.000
methionine adenosyltransferase
0.000
creatine kinase
0.000
kinesin
0.000
GABA transaminase
0.000
beta-glucosidase
0.000
more...
Compound
Baclofen
0.003
Tizanidine
0.001
Botulinum toxin type A
0.001
Dantrolene sodium
0.000
Dantrolene
0.000
F-413
0.000
Ketazolam
0.000
phenol
0.000
GABA
0.000
GABA
0.000
Tetrahydrocannabinol
0.000
N-acetylaspartic acid
0.000
N-acetylaspartic acid
0.000
gamma-aminobutyric acid
0.000
Pantothenate
0.000
Epothilone D
0.000
Cannabidiol
0.000
Memantine
0.000
Spartin
0.000
Clin
0.000
T10
0.000
Allergan
0.000
Interferon beta-1b
0.000
Cyclobenzaprine
0.000
6-pyruvoyltetrahydropterin
0.000
PMP
0.000
Dibenzyline
0.000
Diphenhydramine
0.000
AAA
0.000
Microcephalin
0.000
S-sulfocysteine
0.000
Dec
0.000
Geigy
0.000
His
0.000
T 12
0.000
Cyproheptadine
0.000
Trihexyphenidyl
0.000
2,3-diaminopropanoic acid
0.000
Diazepam
0.000
2,3-diaminopropanoic acid
0.000
Tiagabine
0.000
GA1
0.000
hexadecanal
0.000
AEA
0.000
Elan
0.000
GM2
0.000
hexadecanal
0.000
Guanidinoacetic acid
0.000
Elan
0.000
Dihydroergotamine
0.000
Riluzole
0.000
glutamate
0.000
A-7
0.000
Palmitoylethanolamide
0.000
Guanabenz
0.000
AG-3
0.000
Amantadine
0.000
Amantadine
0.000
Benzocaine
0.000
5-hydroxytryptophan
0.000
N-acetylaspartate
0.000
5-HTP
0.000
Amantadine
0.000
AEA
0.000
5-HTP
0.000
folinic acid
0.000
A101
0.000
T11
0.000
TCC
0.000
Vigabatrin
0.000
Moxonidine
0.000
L-DOPA
0.000
Amantadine
0.000
Pyridostigmine
0.000
4-AP
0.000
RELA
0.000
R 2010
0.000
Clonazepam
0.000
IMP
0.000
5-formyltetrahydrofolate
0.000
more...