Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0026838 (spasticity)
6,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 391 MRI 238 axonal 141 Mol 116 X-linked 109 GABA 92 She 90 spastin 80 CSF 79 strabismus 42 SCI 34 endoplasmic reticulum 33 SPG11 31 hypoxanthine-guanine phosphoribosyltransferase 30 THC 27 fatty aldehyde dehydrogenase 27 SPG3A 26 SACS 26 Rett syndrome 25 SPAST 25 Hip 24 X-linked recessive 24 CB1 24 collagen 22 KCC2 22 ALS 21 A-I 21 SPG7 20 HSP 20 MECP2 20 Pol 19 CB2 19 ATPase 19 MAS 19 MIM 18 T10 17 REEP1 17 glial fibrillary acidic protein 17 cannabinoid receptor 17 L1 cell adhesion molecule 17 CBD 16 ADL 16 TSP 16 ATL1 16 ubiquitin 16 ATP 15 AAA 15 L1CAM 15 tap 15 SPG10 14 ANOVA 14 ALDH3A2 14 ALD 14 brain-derived neurotrophic factor 14 sit 14 MLC1 14 Cx47 14 KIF1A 14 atlastin-1 13 asymmetrical 13 SPG6 12 cytokine 12 T12 12 substance P 12 KIF5A 11 PLA2G6 11 SPG3 11 B12 11 Silver syndrome 11 interferon 11 ROM 10 thyroid hormone 10 fused 10 NMDA receptor 10 threonine 10 PLP1 10 Mot 10 TRH 10 fatty acid hydroxylase 10 monocarboxylate transporter 8 10 more...

Disease cerebral palsy 913 stroke 807 multiple sclerosis 627 spastic paraplegia 235 epilepsy 233 depression 206 mental retardation 200 mental retardation 196 myelopathy 171 Hereditary spastic paraplegia 159 developmental delay 148 amyotrophic lateral sclerosis 146 hemiparesis 133 dementia 130 paraplegia 122 tetraplegia 122 chronic pain 105 cognitive impairment 105 encephalopathy 98 spastic diplegia 89 Parkinson's disease 85 nystagmus 83 neuropathy 82 dysphagia 79 muscular atrophy 73 scoliosis 73 incontinence 72 leukoencephalopathy 71 optic atrophy 69 cancer 68 decubitus 68 neurological disease 66 SPG4 66 parkinsonism 66 hydrocephalus 65 peripheral neuropathy 63 coma 62 Cannabis 57 brain atrophy 55 movement disorder 55 tumor 52 incontinence 48 leukodystrophy 48 choreoathetosis 48 strabismus 47 motor neuron disease 47 migraine 46 ichthyosis 43 macrocephaly 42 hypertension 39 neurogenic bladder 39 ischemia 37 primary lateral sclerosis 37 Lesch-Nyhan syndrome 36 ichthyosis 36 encephalomyelitis 35 HAM 33 SPG11 31 diplegia 31 blindness 31 severe mental retardation 31 genetic disorder 30 polyneuropathy 29 dyskinesia 29 deafness 29 dysplasia 29 Alzheimer's disease 28 apraxia 28 fits 28 osteoporosis 28 sexual dysfunction 27 Rett syndrome 27 malnutrition 27 THC 27 respiratory failure 26 syringomyelia 25 SACS 25 myopathy 25 trigeminal neuralgia 25 arthrodesis 25 more...

Symptom spasticity 6471 pain 912 weakness 672 ataxia 439 dystonia 431 seizures 363 hypertonia 218 hypotonia 183 fatigue 172 hemiplegia 167 spasm 149 tremor 146 paresis 131 paraparesis 129 clonus 128 dysarthria 120 cerebellar ataxia 108 anesthesia 77 headache 77 myoclonus 61 functional recovery 61 athetosis 54 sleepiness 52 blepharospasm 51 muscle stiffness 47 nausea 42 Spastic 41 constipation 41 analgesia 37 dizziness 31 shoulder pain 31 abnormal gait 30 nausea and vomiting 29 chorea 28 back pain 28 vomiting 27 agitation 26 paresthesia 26 discomfort 25 numbness 25 discomfort 25 anorexia 24 insomnia 24 ophthalmoplegia 24 bradykinesia 24 low back pain 23 joint stiffness 22 torticollis 21 thinning 21 cancer pain 19 asthenia 18 drooling 18 muscle rigidity 18 fasciculation 16 ataxic gait 15 incoordination 15 lethargy 15 myalgia 15 cough 15 dyspnea 14 muscle cramps 13 dysesthesia 13 cachexia 12 clumsiness 12 neck pain 11 hypothermia 10 intention tremor 10 dysuria 9 vertigo 9 twitching 9 diarrhea 8 neurological disability 8 neuralgia 8 exhaustion 8 arthralgia 8 hepatosplenomegaly 7 splenomegaly 7 Spastic paraparesis 7 hip pain 6 consciousness disturbance 6 more...

Drug CSF 80 Posture 42 Botox 36 9-THC 33 BoNT/A 26 BOTOX 19 Clonidine 17 Dermatol 17 Dantrolene sodium 16 Lioresal 14 Myobloc 9 lysine 8 ABC 7 Dantrium 7 Diphenhydramine 7 Gabapentin 7 Nabilone 6 Monit 6 Sirdalud 6 caffeine 5 PCP 5 MRC 5 TMS 5 nitroglycerin 4 Tizanidine hydrochloride 4 Phenytoin 4 Cardiovasc 3 CTX 3 Progabide 3 Eperisone hydrochloride 3 CVA 3 Modafinil 3 Xanthium 2 Frontal 2 Nitric Oxide 2 Metrizamide 2 CAM 2 Azithromycin 2 Albumin 2 Glycerol 2 Zmax 2 HCH 2 Interferon beta 2 Bayer 2 Trimethoprim-sulfamethoxazole 2 Bactrim 2 EHDP 1 PFA 1 DPA 1 Iophendylate 1 Orphenadrine citrate 1 Horizon 1 ampicillin 1 Photofrin 1 Glutamic acid 1 Leaf 1 Natalizumab 1 Miglustat 1 Dibenzyline 1 Rolipram 1 Prograf 1 lactose 1 Rimonabant 1 Ditropan 1 THA 1 Foscavir 1 Adriamycin 1 Cimetidine 1 Bupivacaine 1 Carbidopa 1 MDS 1 Growth hormone 1 Idebenone 1 Dihydroergotamine 1 Check 1 Tacrolimus 1 Acyclovir 1 ascorbate 1 Coumadin 1 NADH 1 more...

Enzyme botulinum neurotoxin 103 ATPase 21 arginase 19 hypoxanthine-guanine phosphoribosyltransferase 18 complex I 11 hexosaminidase 9 creatine kinase 9 acetylcholinesterase 9 CYP7B1 9 sulfatase 7 superoxide dismutase 7 aspartyl-tRNA synthetase 7 CYP27A1 7 focal adhesion kinase 7 galactocerebrosidase 7 ERK 6 SCS 6 cholinesterase 6 catalase 6 pantothenate kinase 5 arylsulfatase A 5 alkaline phosphatase 5 PCP 5 RNA polymerase 5 ACE 4 branching enzyme 4 glutaryl-CoA dehydrogenase 4 beta-galactosidase 4 aspartoacylase 4 kinesin 4 mitogen-activated protein kinase 3 neuropathy target esterase 3 ornithine transcarbamylase 3 beta-glucosidase 3 methylenetetrahydrofolate reductase 3 glucocerebrosidase 3 pyruvate dehydrogenase 3 transcriptase 3 phospholipase A2 3 NO synthase 3 Lod 3 alanine aminotransferase 3 cytochrome oxidase 3 cathepsin D 3 dopamine beta-hydroxylase 3 choline acetyltransferase 3 reverse transcriptase 3 asparagine synthetase 3 methylenetetrahydrofolate reductase 3 adenosine deaminase 2 GTP cyclohydrolase I 2 mu-calpain 2 aldehyde dehydrogenase 2 adenine phosphoribosyltransferase 2 collagenase 2 caspase-3 2 PDH 2 phospholipase C 2 alpha-L-fucosidase 2 neuraminidase 2 phosphodiesterase 2 P-glycoprotein 2 CD10 2 proteasome 2 fatty acyl-CoA reductase 2 aldehyde dehydrogenase 2 APC 2 sialidase 2 aldehyde dehydrogenase 2 biotinidase 2 protein kinase 2 tetanus neurotoxin 2 succinic semialdehyde dehydrogenase 2 thromboplastin 2 NADPH-diaphorase 2 beta-glucosidase 2 hyaluronidase 2 hyaluronidase 2 ceruloplasmin 2 citrate synthase 2 more...

Compound Clin 481 Dec 415 Baclofen 160 GABA 97 GABA 94 DNA 86 phenol 84 His 72 sodium 64 gamma-aminobutyric acid 53 glutamate 50 calcium 47 water 42 Botulinum toxin type A 41 oxygen 38 glucose 38 iron 30 potassium 29 Tizanidine 29 arginine 29 urea 24 5-HT 20 ammonia 19 Dantrolene 19 ethanol 18 Diazepam 18 T10 17 phosphate 16 ATP 15 AAA 15 serine 15 L-DOPA 14 creatinine 12 Tetrahydrocannabinol 11 nitric oxide 11 Phe 11 NMDA 11 acetate 11 PMA 10 threonine 10 Dantrolene sodium 10 Neuronal 10 Optimal 10 TRH 10 Gly 10 hydrogen 10 iodine 9 Memantine 9 5-hydroxytryptophan 9 N-acetylaspartate 9 lysine 9 alanine 9 nitrogen 8 GM2 8 barium 8 TNF 8 Cannabidiol 8 noradrenaline 7 glutamine 7 AMPA 7 glycerol 7 Allergan 7 IMP 7 sulfate 7 Diphenhydramine 7 AEA 7 PMP 6 Pantothenate 6 phosphorus 6 folinic acid 6 T11 6 methionine 6 silver 6 copper 6 PEG 6 cysteine 6 ornithine 5 GTP 5 hexane 5 salt 5 more...

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