UMLS:C0026838 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026838 (spasticity)
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Human Gene/Protein
B3GalNAc-T2	12.3
Phospholipase DDHD2	12.3
SPG3A protein	12.3
KIAA0415	11.7
reticulon 2	11.5
SPG3	11.4
NIPA1 protein	11.3
Rab40A	11.3
FSP2	11.3
GDAP2	11.3
Kinesin family member 5A	11.3
LYR motif-containing protein 7	11.3
SPG3A	11.2
SPG42	10.9
SPG6	10.9
SPG10	10.9
SPG8	10.9
C19orf2	10.7
ZFYVE27	10.7
KIAA1840	10.7
SPAST	10.5
ATL1	10.5
atlastin-1	10.4
SPG11	10.4
ARSACS	10.3
TSEN34	10.3
REEP1	10.3
DDHD1	10.3
FLJ10737	10.3
TIZ	10.3
RAB9B	10.3
ALDH3A2	10.2
DDHD2	10.2
spastin	10.1
fatty aldehyde dehydrogenase	10.1
RTN2	10.1
ZFYVE26	10.1
ARD1A	9.9
ATAD3A protein	9.9
DNAJC11	9.9

Disease
Spastic quadriplegic cerebral palsy	12.3
Exacerbation of multiple sclerosis	12.3
IAHSP	12.3
SPG19	12.3
Gaze palsy	12.3
Pectoralis minor syndrome	12.3
Muscle tone abnormalities	12.3
Fitzsimmons syndrome	12.3
Miles-Carpenter syndrome	11.7
SPG12	11.6
SPG30	11.5
SPG8	11.5
SPG33	11.3
Pure hereditary spastic paraplegia	11.3
SPG6	11.1
SPG28	11.1
SPG9	11.0
SPG10	11.0
Hereditary spastic paraplegia	11.0
Spastic ataxia	10.9
SPG4	10.9
SPG31	10.7
Post-thoracotomy pain syndrome	10.7
SPG27	10.7
Shoulder-hand syndrome	10.7
SPG13	10.7
SPG24	10.7
Upper motor neuron disease	10.7
SPG14	10.7
ENFL2	10.7
Spastic cerebral palsy	10.6
SPG11	10.5
SPG21	10.3
SCA18	10.3
PMLD1	10.3
Localized tetanus	10.3
Staphylococcal meningitis	10.3
HMN V	10.3
SACS	10.3
SPG1	10.2

Symptom
spasticity	12.3
Decerebrate posture	12.3
Clasp-knife phenomenon	12.3
Abnormal muscle tone	12.3
Spastic hemiplegia	10.8
Spastic	10.1
Spastic paraparesis	10.0
athetosis	10.0
hypertonia	9.7
clonus	9.7
Flaccidity	9.7
Pyramidal signs	9.7
hemiathetosis	9.7
Ankle stiffness	9.1
Truncal ataxia	8.9
abnormal reflex	8.8
Central pain	8.6
Opisthotonus	8.6
Other pain	8.6
Neurogenic pain	8.4
disturbed speech	8.3
dystonia	8.0
Spasmodic dysphonia	8.0
blepharospasm	7.9
Hyperekplexia	7.9
paraparesis	7.8
hemiplegia	7.7
Procedural pain	7.7
hemihypesthesia	7.7
muscle stiffness	7.6
Lhermitte's sign	7.5
Central post-stroke pain	7.5
feeling sick	7.4
Peripheral neuropathic pain	7.3
dysarthria	7.3
abdominal rigidity	7.3
hypotonia	7.3
cerebellar ataxia	7.2
PAIN	7.2
intention tremor	7.1

Enzyme
EC 1.2.1.48	10.7
calpain B	9.7
plasmanylethanolamine desaturase	9.3
methylglutaconyl coenzyme A hydratase	9.1
pterin-4alpha-carbinolamine dehydratase	8.7
CYP7B1	8.5
botulinum neurotoxin	8.1
5,10-methenyltetrahydrofolate synthetase	7.7
alkylglycerol monooxygenase	7.7
fatty acyl-CoA reductase	7.3
aspartyl-tRNA synthetase	7.2
methionyl-tRNA formyltransferase	6.8
m-AAA protease	6.7
aspartoacylase	6.7
pantothenate kinase	6.6
glutaryl-CoA dehydrogenase	6.5
galactocerebrosidase	6.4
Lod	6.2
CYP27A1	6.0
dihydroxyacetone phosphate acyltransferase	5.9
splicing endonuclease	5.9
tetanus neurotoxin	5.6
DSR	5.4
arylsulfatase A	5.3
phosphoserine aminotransferase	5.3
HOA	5.3
arginyl-tRNA synthetase	5.1
guanidinoacetate methyltransferase	5.1
hypoxanthine-guanine phosphoribosyltransferase	5.1
succinic semialdehyde dehydrogenase	5.0
FADS	5.0
branching enzyme	5.0
asparagine synthetase	4.9
SCS	4.9
TSR	4.8
glutamyl-tRNA synthetase	4.7
sepiapterin reductase	4.7
biotinidase	4.7
arginase	4.6
alanyl-tRNA synthetase	4.5