Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026838 (
spasticity
)
6,471
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
391
MRI
238
axonal
141
Mol
116
X-linked
109
GABA
92
She
90
spastin
80
CSF
79
strabismus
42
SCI
34
endoplasmic reticulum
33
SPG11
31
hypoxanthine-guanine phosphoribosyltransferase
30
THC
27
fatty aldehyde dehydrogenase
27
SACS
26
SPG3A
26
SPAST
25
Rett syndrome
25
X-linked recessive
24
CB1
24
Hip
24
KCC2
22
collagen
22
ALS
21
A-I
21
HSP
20
SPG7
20
MECP2
20
ATPase
19
CB2
19
MAS
19
Pol
19
MIM
18
REEP1
17
glial fibrillary acidic protein
17
T10
17
cannabinoid receptor
17
L1 cell adhesion molecule
17
more...
Disease
cerebral palsy
913
stroke
807
multiple sclerosis
627
spastic paraplegia
235
epilepsy
233
depression
206
mental retardation
200
mental retardation
196
myelopathy
171
Hereditary spastic paraplegia
159
developmental delay
148
amyotrophic lateral sclerosis
146
hemiparesis
133
dementia
130
paraplegia
122
tetraplegia
122
cognitive impairment
105
chronic pain
105
encephalopathy
98
spastic diplegia
89
Parkinson's disease
85
nystagmus
83
neuropathy
82
dysphagia
79
muscular atrophy
73
scoliosis
73
incontinence
72
leukoencephalopathy
71
optic atrophy
69
decubitus
68
cancer
68
neurological disease
66
SPG4
66
parkinsonism
66
hydrocephalus
65
peripheral neuropathy
63
coma
62
Cannabis
57
movement disorder
55
brain atrophy
55
more...
Symptom
spasticity
6471
pain
912
weakness
672
ataxia
439
dystonia
431
seizures
363
hypertonia
218
hypotonia
183
fatigue
172
hemiplegia
167
spasm
149
tremor
146
paresis
131
paraparesis
129
clonus
128
dysarthria
120
cerebellar ataxia
108
anesthesia
77
headache
77
myoclonus
61
functional recovery
61
athetosis
54
sleepiness
52
blepharospasm
51
muscle stiffness
47
nausea
42
Spastic
41
constipation
41
analgesia
37
dizziness
31
shoulder pain
31
abnormal gait
30
nausea and vomiting
29
back pain
28
chorea
28
vomiting
27
paresthesia
26
agitation
26
discomfort
25
numbness
25
more...
Drug
CSF
80
Posture
42
Botox
36
9-THC
33
BoNT/A
26
BOTOX
19
Dermatol
17
Clonidine
17
Dantrolene sodium
16
Lioresal
14
Myobloc
9
lysine
8
Gabapentin
7
Diphenhydramine
7
ABC
7
Dantrium
7
Sirdalud
6
Monit
6
Nabilone
6
PCP
5
MRC
5
TMS
5
caffeine
5
Tizanidine hydrochloride
4
nitroglycerin
4
Phenytoin
4
CVA
3
Eperisone hydrochloride
3
Modafinil
3
Progabide
3
CTX
3
Cardiovasc
3
Metrizamide
2
Interferon beta
2
Nitric Oxide
2
CAM
2
Trimethoprim-sulfamethoxazole
2
Bactrim
2
Xanthium
2
Albumin
2
more...
Enzyme
botulinum neurotoxin
103
ATPase
21
arginase
19
hypoxanthine-guanine phosphoribosyltransferase
18
complex I
11
hexosaminidase
9
creatine kinase
9
acetylcholinesterase
9
CYP7B1
9
sulfatase
7
superoxide dismutase
7
aspartyl-tRNA synthetase
7
focal adhesion kinase
7
galactocerebrosidase
7
CYP27A1
7
catalase
6
SCS
6
ERK
6
cholinesterase
6
alkaline phosphatase
5
arylsulfatase A
5
PCP
5
RNA polymerase
5
pantothenate kinase
5
ACE
4
glutaryl-CoA dehydrogenase
4
aspartoacylase
4
branching enzyme
4
kinesin
4
beta-galactosidase
4
Lod
3
ornithine transcarbamylase
3
mitogen-activated protein kinase
3
neuropathy target esterase
3
glucocerebrosidase
3
phospholipase A2
3
NO synthase
3
cytochrome oxidase
3
alanine aminotransferase
3
dopamine beta-hydroxylase
3
more...
Compound
Clin
481
Dec
415
Baclofen
160
GABA
97
GABA
94
DNA
86
phenol
84
His
72
sodium
64
gamma-aminobutyric acid
53
glutamate
50
calcium
47
water
42
Botulinum toxin type A
41
glucose
38
oxygen
38
iron
30
arginine
29
potassium
29
Tizanidine
29
urea
24
5-HT
20
Dantrolene
19
ammonia
19
ethanol
18
Diazepam
18
T10
17
phosphate
16
ATP
15
serine
15
AAA
15
L-DOPA
14
creatinine
12
Tetrahydrocannabinol
11
nitric oxide
11
NMDA
11
Phe
11
acetate
11
hydrogen
10
Neuronal
10
more...