Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026838 (spasticity)
6,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 391
MRI 238
axonal 141
Mol 116
X-linked 109
GABA 92
She 90
spastin 80
CSF 79
strabismus 42
SCI 34
endoplasmic reticulum 33
SPG11 31
hypoxanthine-guanine phosphoribosyltransferase 30
THC 27
fatty aldehyde dehydrogenase 27
SACS 26
SPG3A 26
SPAST 25
Rett syndrome 25
X-linked recessive 24
CB1 24
Hip 24
KCC2 22
collagen 22
ALS 21
A-I 21
HSP 20
SPG7 20
MECP2 20
ATPase 19
CB2 19
MAS 19
Pol 19
MIM 18
REEP1 17
glial fibrillary acidic protein 17
T10 17
cannabinoid receptor 17
L1 cell adhesion molecule 17
more...
Disease
cerebral palsy 913
stroke 807
multiple sclerosis 627
spastic paraplegia 235
epilepsy 233
depression 206
mental retardation 200
mental retardation 196
myelopathy 171
Hereditary spastic paraplegia 159
developmental delay 148
amyotrophic lateral sclerosis 146
hemiparesis 133
dementia 130
paraplegia 122
tetraplegia 122
cognitive impairment 105
chronic pain 105
encephalopathy 98
spastic diplegia 89
Parkinson's disease 85
nystagmus 83
neuropathy 82
dysphagia 79
muscular atrophy 73
scoliosis 73
incontinence 72
leukoencephalopathy 71
optic atrophy 69
decubitus 68
cancer 68
neurological disease 66
SPG4 66
parkinsonism 66
hydrocephalus 65
peripheral neuropathy 63
coma 62
Cannabis 57
movement disorder 55
brain atrophy 55
more...
Symptom
spasticity 6471
pain 912
weakness 672
ataxia 439
dystonia 431
seizures 363
hypertonia 218
hypotonia 183
fatigue 172
hemiplegia 167
spasm 149
tremor 146
paresis 131
paraparesis 129
clonus 128
dysarthria 120
cerebellar ataxia 108
anesthesia 77
headache 77
myoclonus 61
functional recovery 61
athetosis 54
sleepiness 52
blepharospasm 51
muscle stiffness 47
nausea 42
Spastic 41
constipation 41
analgesia 37
dizziness 31
shoulder pain 31
abnormal gait 30
nausea and vomiting 29
back pain 28
chorea 28
vomiting 27
paresthesia 26
agitation 26
discomfort 25
numbness 25
more...
Drug
CSF 80
Posture 42
Botox 36
9-THC 33
BoNT/A 26
BOTOX 19
Dermatol 17
Clonidine 17
Dantrolene sodium 16
Lioresal 14
Myobloc 9
lysine 8
Gabapentin 7
Diphenhydramine 7
ABC 7
Dantrium 7
Sirdalud 6
Monit 6
Nabilone 6
PCP 5
MRC 5
TMS 5
caffeine 5
Tizanidine hydrochloride 4
nitroglycerin 4
Phenytoin 4
CVA 3
Eperisone hydrochloride 3
Modafinil 3
Progabide 3
CTX 3
Cardiovasc 3
Metrizamide 2
Interferon beta 2
Nitric Oxide 2
CAM 2
Trimethoprim-sulfamethoxazole 2
Bactrim 2
Xanthium 2
Albumin 2
more...
Enzyme
botulinum neurotoxin 103
ATPase 21
arginase 19
hypoxanthine-guanine phosphoribosyltransferase 18
complex I 11
hexosaminidase 9
creatine kinase 9
acetylcholinesterase 9
CYP7B1 9
sulfatase 7
superoxide dismutase 7
aspartyl-tRNA synthetase 7
focal adhesion kinase 7
galactocerebrosidase 7
CYP27A1 7
catalase 6
SCS 6
ERK 6
cholinesterase 6
alkaline phosphatase 5
arylsulfatase A 5
PCP 5
RNA polymerase 5
pantothenate kinase 5
ACE 4
glutaryl-CoA dehydrogenase 4
aspartoacylase 4
branching enzyme 4
kinesin 4
beta-galactosidase 4
Lod 3
ornithine transcarbamylase 3
mitogen-activated protein kinase 3
neuropathy target esterase 3
glucocerebrosidase 3
phospholipase A2 3
NO synthase 3
cytochrome oxidase 3
alanine aminotransferase 3
dopamine beta-hydroxylase 3
more...
Compound
Clin 481
Dec 415
Baclofen 160
GABA 97
GABA 94
DNA 86
phenol 84
His 72
sodium 64
gamma-aminobutyric acid 53
glutamate 50
calcium 47
water 42
Botulinum toxin type A 41
glucose 38
oxygen 38
iron 30
arginine 29
potassium 29
Tizanidine 29
urea 24
5-HT 20
Dantrolene 19
ammonia 19
ethanol 18
Diazepam 18
T10 17
phosphate 16
ATP 15
serine 15
AAA 15
L-DOPA 14
creatinine 12
Tetrahydrocannabinol 11
nitric oxide 11
NMDA 11
Phe 11
acetate 11
hydrogen 10
Neuronal 10
more...