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Query: UMLS:C0026838 (spasticity)
 6,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a patient with Holmes-Adie syndrome, and in another with tabes dorsalis, a transverse cord lesion resulted in a severe, but flaccid paraplegia with absent tendon reflexes. Flexor spasms were severe in both patients, but spasticity was absent. The significance of these observations is discussed in relation to the functional and anatomical disorder in these two syndromes.
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PMID:Flaccid paraplegia: a feature of spinal cord lesions in Holmes-Adie syndrome and tabes dorsalis. 114 18

BEST REMEMBERED FOR his description of the dermatomes in man, Otfrid Foerster was also an adept neurosurgeon and an innovative experimental neurophysiologist. As a neurologist, his contributions included conceptualizing rhizotomy as a cure for spasticity, anterolateral cordotomy for pain, the hyperventilation test in epilepsy, Foerster's syndrome, and the first electrocorticogram of a brain tumor. As a neurosurgeon, Foerster was able to excise intraventricular, hypophyseal, and quadrigeminal lesions and to perform epilepsy surgery under primitive conditions without clips, diathermy, or suction. The results were good and reflected his consummate knowledge of neuroanatomy and neurophysiology. As an investigator, Foerster emphasized clinically orientated neurophysiology and was able to forge a link between his observations and proposed methods of treatment. A prolific writer, he published more than 300 scientific monographs encompassing every aspect of the nervous system, including tabes, movement disorders, spasticity, extrapyramidal diseases, dermatomes, epilepsy, cortical localization, brain tumors, peripheral nerve injuries, and pain. Foerster's superb command of languages led to his popularity as a speaker in Europe and North America. Students who flocked to learn from his encyclopedic knowledge and skill were privy to Foerster's legendary hospitality and charm. A man of delicate constitution, he was single-minded in his quest to unravel the mysteries of the nervous system. The inscription "Patriae scientiae inserviendo" or "In the service of science and Fatherland" was chosen by Foerster for his Institute of Neurology and is a fitting memorial to this neurosurgical giant.
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PMID:The contributions of Otfrid Foerster (1873-1941) to neurology and neurosurgery. 1205 Nov 94

At the beginning of the 20th century, the development of safer anesthesia, antiseptic techniques, and meticulous surgical dissection led to a substantial decrease in operative risk. In turn, the scope of surgery expanded to include elective procedures performed with the intention of improving the quality of life of patients. Between 1908 and 1912, Harvey Cushing performed 3 dorsal rhizotomies to improve the quality of life of 3 patients with debilitating neuralgia: a 54-year-old man with "lightning" radicular pain from tabes dorsalis, a 12-year-old boy cutaneous hyperesthesia and spasticity in his hemiplegic arm, and a 61-year-old man with postamputation neuropathic pain. Symptomatic improvement was seen postoperatively in the first 2 cases, although the third patient continued to have severe pain. Cushing also removed a prominent spinous process from each of 2 patients with debilitating headaches; both patients, however, experienced only minimal postoperative improvement. These cases, which have not been previously published, highlight Cushing's views on the role of surgery and illustrate the broader movement that occurred in surgery at the time, whereby elective procedures for quality of life became performed and accepted.
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PMID:"Fulfilling the chief of his duties as a physician": Harvey Cushing, selective dorsal rhizotomy and elective spine surgery for quality of life. 2125 Aug 16