Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026838 (spasticity)
 6,471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intrathecal delivery of baclofen using a subcutaneous pump is an effective long-term treatment for spasticity. Infections of the pocket, however, are often hard to eliminate with intravenous antibiotics. If a 2-stage procedure involving removal of the pump and baclofen withdrawal will create serious problems for the patient, infections can be treated with repetitive local application of gentamicin-impregnated collagen fleece.
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PMID:In situ treatment of an infected intrathecal baclofen pump implant with gentamicin-impregnated collagen fleece. 1973 88