Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026837 (muscle rigidity)
 1,077 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 63
She 40
creatine kinase 38
ATP 28
glutamic acid decarboxylase 26
MRI 25
myosin 22
ryanodine receptor 15
Mol 13
CPK 13
RYR1 12
myoglobin 11
Pol 11
GABA 10
tyrosine hydroxylase 9
ATPase 7
cardiac muscle 7
CO2 7
insulin 7
NMS 7
amphiphysin 6
metabotropic glutamate receptor 6
opioid receptor 6
lactate dehydrogenase 6
ADP 5
hemoglobin 5
Gen 5
NMDA receptor 5
Mot 5
IMP 4
RyR1 4
synuclein 4
alpha-synuclein 4
calcium channel 4
aspartate aminotransferase 4
stiff person syndrome 4
GAD 4
CYP2D6 4
prolactin 4
AIDA 3
strabismus 3
GAD65 3
glial cell line-derived neurotrophic factor 3
tropomyosin 3
LDH 3
ASD 3
proenkephalin 3
thyroid hormone 3
CSF 3
ASA 3
axonal 3
ANOVA 3
collagen 3
fibrinogen 3
SCH 3
5-HT1A 3
mGluR5 3
AMP 3
dilute 3
GSH 2
glutamate receptor 2
adenylate kinase 2
glyceraldehyde 3-phosphate dehydrogenase 2
huntingtin 2
SOD 2
VIM 2
elastin 2
PNP 2
C-reactive protein 2
NADH 2
troponin C 2
chronic renal failure 2
cardiac myosin binding protein-C 2
CBD 2
FDG 2
BIS 2
neurotrophin-4 2
HAL 2
dihydropyridine receptor 2
5-hydroxytryptamine 2
more...
Disease
Parkinson's disease 166
malignant hyperthermia 124
NMS 68
parkinsonism 59
depression 53
akinesia 47
dementia 33
psychosis 25
catalepsy 23
fits 19
schizophrenia 19
dysphagia 18
coma 18
Alzheimer's disease 18
diabetes 17
tetanus 17
progressive supranuclear palsy 16
myopathy 15
dyskinesia 14
cognitive impairment 14
hypertension 14
stroke 14
SPS 14
sepsis 13
renal failure 13
confusion 11
sepsis 11
dehydration 11
Syndrome 11
respiratory failure 10
delirium 10
cancer 10
acute renal failure 10
hallucinations 10
multiple sclerosis 10
erectile dysfunction 9
disseminated intravascular coagulation 9
cold 9
mutism 9
disorientation 8
aggression 8
Huntington's disease 8
brain atrophy 8
movement disorder 8
apraxia 8
incontinence 7
NMS 7
mental illness 7
thrombocytopenia 7
epilepsy 7
neurological disease 6
pneumonia 6
breast cancer 6
physical dependence 6
Tension 6
ischemia 6
encephalomyelitis 6
bipolar disorder 6
Autism 6
trismus 6
autism 6
sinus tachycardia 5
hypothyroidism 5
neuroticism 5
major depressive disorder 5
cerebral palsy 5
heart failure 5
tardive dyskinesia 5
aphasia 5
rare disease 5
prolapse 5
porcine stress syndrome 4
mental retardation 4
aspiration pneumonia 4
malnutrition 4
GAD 4
suicide 4
SEM 4
choreoathetosis 4
genetic disorder 4
more...
Symptom
muscle rigidity 1077
tremor 141
anesthesia 134
rigors 99
bradykinesia 93
pain 32
muscle stiffness 31
seizures 29
agitation 25
analgesia 23
tachypnea 22
spasm 19
weakness 19
hypercapnia 18
spasticity 18
myoclonus 18
catatonia 17
vomiting 17
dystonia 17
ataxia 14
nausea 13
fatigue 12
insomnia 11
dyspnea 10
cerebellar ataxia 9
sleepiness 8
clonus 7
collapse 7
hypertonia 7
diarrhea 6
myalgia 6
dysarthria 6
abdominal pain 6
drooling 5
muscle cramps 5
hypothermia 5
exhaustion 5
excessive sweating 5
respiratory distress 5
consciousness disturbance 5
Extrapyramidal symptoms 4
syncope 4
headache 4
hypotonia 4
personality change 4
Rest tremor 4
nausea and vomiting 4
chorea 3
cyanosis 3
numbness 3
dizziness 3
discomfort 3
motor symptom 3
clumsiness 3
twitching 3
pallor 3
forgetfulness 3
incoordination 3
discomfort 3
chest pain 3
apathy 3
ataxic gait 2
low back pain 2
leg pain 2
constipation 2
ophthalmoplegia 2
anorexia 2
paresis 2
erythema 2
abnormal gait 2
peau d'orange 2
blepharospasm 2
acute pain 2
cachexia 2
auditory hallucination 2
fasciculation 2
acute abdomen 2
Marked rigidity 1
sneezing 1
Grimace 1
more...
Drug
caffeine 22
Dantrolene sodium 7
Fentanyl 6
Propofol 4
CSF 3
Cardiovasc 3
lysine 3
Sinemet 3
Lisuride 2
Sinemet 2
Ringer's solution 2
Posture 2
Monit 2
Reserpine 2
DEX 2
NADH 2
Abecarnil 2
Sinemet 2
Pramipexole 2
Tandospirone citrate 1
Fluphenazine 1
Vegetamin 1
Thioridazine 1
Piracetam 1
MAP 1
Spectrum 1
pyridoxal phosphate 1
Phenytoin 1
Rocuronium 1
Diurnal 1
Pramipexole 1
Leaf 1
Campath 1
EMD 128130 1
Papaverine 1
Fluorescein 1
Rituximab 1
Campath 1
Iodixanol 1
Gel 1
Moclobemide 1
Alanine 1
MgSO4 1
Benserazide 1
Atropine 1
Nephron 1
vitamin E 1
Iloperidone 1
Tacrolimus 1
Ezetimibe 1
Paliperidone 1
Novafil 1
Tubocurarine 1
Fluorescein 1
Rotigotine 1
Apomorphine 1
Hydroxyzine pamoate 1
Iopentol 1
Oxaliplatin 1
PCP 1
Carbidopa 1
Simvastatin 1
CDP 1
Iopromide 1
CIA 1
BOTOX 1
Mirapex 1
Flexeril 1
Medetomidine 1
Ethanol 1
Tetanus toxoid 1
CTA 1
ascorbate 1
Atipamezole 1
Bupivacaine 1
Enzyme
creatine kinase 73
monoamine oxidase 13
tyrosine hydroxylase 9
ATPase 8
lactate dehydrogenase 6
aspartate aminotransferase 5
myosin ATPase 4
alanine aminotransferase 4
cholinesterase 3
glyceraldehyde-3-phosphate dehydrogenase 3
acid phosphatase 2
BIS 2
acetylcholinesterase 2
superoxide dismutase 2
adenylate kinase 2
ceruloplasmin 2
glycerol-3-phosphate dehydrogenase 2
glycerol-3-phosphate dehydrogenase 2
thromboplastin 2
MAP 1
RNase 1
pyridoxal kinase 1
diaphorase 1
catalase 1
PCP 1
glyceraldehyde-3-phosphate dehydrogenase 1
DOPA decarboxylase 1
caspase-3 1
MEK 1
alpha-amylase 1
glyceraldehyde-3-phosphate dehydrogenase 1
CD10 1
dihydrofolate reductase 1
ERK 1
glyceraldehyde-3-phosphate dehydrogenase 1
deoxyribonuclease 1
DMT 1
focal adhesion kinase 1
cathepsin B 1
protein kinase 1
phosphodiesterase 1
AMPK 1
AMP deaminase 1
xanthine oxidase 1
DNase 1
SPS 1
protein kinase C 1
demethylase 1
PTA 1
apyrase 1
choline acetyltransferase 1
thyroid peroxidase 1
glucose-6-phosphate dehydrogenase 1
CPT 1
mitogen-activated protein kinase 1
tryptophan synthase 1
glutamate decarboxylase 1
AST 1
RNase 1
GSK 1
deoxyribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
hyaluronidase 1
NADH-cytochrome b5 reductase 1
ribonuclease 1
P-glycoprotein 1
pyruvate kinase 1
asparaginyl-tRNA synthetase 1
AMPK 1
MPP 1
phospholipase C 1
hyaluronidase 1
ribonuclease 1
AMP-activated protein kinase 1
Compound
calcium 65
Clin 61
Dec 57
oxygen 46
sodium 42
ATP 28
CO2 22
caffeine 22
L-DOPA 20
water 19
His 17
creatinine 16
glucose 12
GABA 10
MPTP 10
Alfentanil 10
phosphate 10
GABA 10
Dantrolene 9
5-HT 8
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8
DSM 8
DNA 8
tyrosine 8
Dantrolene sodium 7
Dopamine 7
ethanol 7
Halothane 7
ADP 6
Haloperidol 6
Haloperidol 6
gamma-aminobutyric acid 6
N2O 6
glutamate 6
Succinylcholine 6
potassium 6
Cardiol 5
ADP 5
Diazepam 5
A 71 5
iron 5
sulfate 5
salt 5
ADP 5
NMDA 5
Remifentanil 5
HCl 4
IMP 4
Morphine 4
arginine 4
ASA 4
Olanzapine 4
Propofol 4
Clozapine 4
nitrogen 4
Ketamine 4
hydrogen 3
lysine 3
m-cresol 3
urea 3
Muscimol 3
cysteine 3
phosphocreatine 3
4-phenyl-1,2,3,6-tetrahydropyridine 3
TSH 3
Dexmedetomidine 3
Mg2+ 3
bromide 3
Dopa 3
Triton X-100 3
Valproic acid 3
glycerol 3
Risperidone 3
AMP 3
DPH 3
tryptophan 3
Baclofen 3
Gly 3
GSH 2
silver 2
more...