Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026837 (
muscle rigidity
)
1,077
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
63
She
40
creatine kinase
38
ATP
28
glutamic acid decarboxylase
26
MRI
25
myosin
22
ryanodine receptor
15
CPK
13
Mol
13
RYR1
12
myoglobin
11
Pol
11
GABA
10
tyrosine hydroxylase
9
NMS
7
ATPase
7
insulin
7
cardiac muscle
7
CO2
7
amphiphysin
6
opioid receptor
6
metabotropic glutamate receptor
6
lactate dehydrogenase
6
ADP
5
Mot
5
hemoglobin
5
Gen
5
NMDA receptor
5
calcium channel
4
synuclein
4
aspartate aminotransferase
4
GAD
4
stiff person syndrome
4
CYP2D6
4
IMP
4
RyR1
4
alpha-synuclein
4
prolactin
4
AIDA
3
more...
Disease
Parkinson's disease
166
malignant hyperthermia
124
NMS
68
parkinsonism
59
depression
53
akinesia
47
dementia
33
psychosis
25
catalepsy
23
fits
19
schizophrenia
19
coma
18
Alzheimer's disease
18
dysphagia
18
diabetes
17
tetanus
17
progressive supranuclear palsy
16
myopathy
15
hypertension
14
SPS
14
dyskinesia
14
cognitive impairment
14
stroke
14
renal failure
13
sepsis
13
dehydration
11
confusion
11
Syndrome
11
sepsis
11
multiple sclerosis
10
hallucinations
10
delirium
10
cancer
10
acute renal failure
10
respiratory failure
10
disseminated intravascular coagulation
9
cold
9
erectile dysfunction
9
mutism
9
disorientation
8
more...
Symptom
muscle rigidity
1077
tremor
141
anesthesia
134
rigors
99
bradykinesia
93
pain
32
muscle stiffness
31
seizures
29
agitation
25
analgesia
23
tachypnea
22
spasm
19
weakness
19
spasticity
18
myoclonus
18
hypercapnia
18
vomiting
17
dystonia
17
catatonia
17
ataxia
14
nausea
13
fatigue
12
insomnia
11
dyspnea
10
cerebellar ataxia
9
sleepiness
8
clonus
7
collapse
7
hypertonia
7
diarrhea
6
dysarthria
6
myalgia
6
abdominal pain
6
respiratory distress
5
exhaustion
5
hypothermia
5
excessive sweating
5
muscle cramps
5
drooling
5
consciousness disturbance
5
more...
Drug
caffeine
22
Dantrolene sodium
7
Fentanyl
6
Propofol
4
Cardiovasc
3
CSF
3
lysine
3
Sinemet
3
Pramipexole
2
Monit
2
DEX
2
Sinemet
2
Sinemet
2
Lisuride
2
Abecarnil
2
NADH
2
Reserpine
2
Posture
2
Ringer's solution
2
Phenytoin
1
Diurnal
1
Fluphenazine
1
Flexeril
1
Piracetam
1
MAP
1
Spectrum
1
Campath
1
Iodixanol
1
Fluorescein
1
Simvastatin
1
CIA
1
Leaf
1
Gel
1
EMD 128130
1
Papaverine
1
Moclobemide
1
MgSO4
1
Benserazide
1
Atropine
1
Ezetimibe
1
more...
Enzyme
creatine kinase
73
monoamine oxidase
13
tyrosine hydroxylase
9
ATPase
8
lactate dehydrogenase
6
aspartate aminotransferase
5
myosin ATPase
4
alanine aminotransferase
4
glyceraldehyde-3-phosphate dehydrogenase
3
cholinesterase
3
glycerol-3-phosphate dehydrogenase
2
ceruloplasmin
2
superoxide dismutase
2
adenylate kinase
2
acetylcholinesterase
2
BIS
2
acid phosphatase
2
glycerol-3-phosphate dehydrogenase
2
thromboplastin
2
caspase-3
1
ribonuclease
1
RNase
1
CD10
1
catalase
1
PCP
1
glyceraldehyde-3-phosphate dehydrogenase
1
RNase
1
deoxyribonuclease
1
glyceraldehyde-3-phosphate dehydrogenase
1
P-glycoprotein
1
cathepsin B
1
phosphodiesterase
1
AMP deaminase
1
xanthine oxidase
1
asparaginyl-tRNA synthetase
1
dihydrofolate reductase
1
DNase
1
SPS
1
choline acetyltransferase
1
thyroid peroxidase
1
more...
Compound
calcium
65
Clin
61
Dec
57
oxygen
46
sodium
42
ATP
28
caffeine
22
CO2
22
L-DOPA
20
water
19
His
17
creatinine
16
glucose
12
phosphate
10
MPTP
10
Alfentanil
10
GABA
10
GABA
10
Dantrolene
9
DSM
8
tyrosine
8
DNA
8
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
8
5-HT
8
Dantrolene sodium
7
Dopamine
7
Halothane
7
ethanol
7
ADP
6
Haloperidol
6
potassium
6
glutamate
6
Succinylcholine
6
N2O
6
gamma-aminobutyric acid
6
Haloperidol
6
Remifentanil
5
ADP
5
ADP
5
salt
5
more...