Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026837 (muscle rigidity)
 1,077 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
Myokinase 12.3
phosphodiesterase 8B 11.5
STHE 10.2
calmodulin-like skin protein 10.0
cardiac myosin binding protein-C 9.9
stiff person syndrome 9.8
SCA8 9.7
CACNL1A3 9.7
Gemin5 9.6
CACNA1S 9.3
cardiac MyBP-C 9.1
HSPG2 9.1
adenosine monophosphate deaminase 8.9
amphiphysin 8.8
ACPT 8.8
H1.5 8.7
RYR1 8.5
GLRA1 8.5
Dermatopontin 8.4
asparaginyl-tRNA synthetase 8.4
tropomyosin isoform 8.4
NMS 8.3
AIDA 8.1
DCI 8.1
thrombospondin-4 8.0
EPM1 7.9
carbonic anhydrase B 7.9
ALF 7.8
CPK 7.8
glutamic acid decarboxylase 7.6
CPT2 7.5
HAL 7.5
FOP 7.4
SYP 7.4
GCH1 7.4
FRP 7.3
5HT1A 7.2
pyridoxal kinase 7.2
NADH diaphorase 7.1
Amphiphysin 7.1
CPT II 7.0
mGluR8 7.0
malin 7.0
ryanodine receptor 6.9
LDH-B 6.9
neurotrophin-4 6.8
Glutamic acid decarboxylase 6.7
DMB 6.7
RyR1 6.7
dihydropyridine receptor 6.7
gephyrin 6.6
HNF4A 6.6
mGluR4 6.6
dopa-responsive dystonia 6.5
DRD1 6.5
mGluR2 6.5
NT-4/5 6.4
5-HT6 6.4
PIF 6.4
AMT 6.4
alpha-tropomyosin 6.4
myosin V 6.3
TH protein 6.3
creatine kinase 6.3
lactate dehydrogenase A 6.2
proenkephalin 6.2
PBI 6.2
mGluR5 6.1
UCHL1 6.0
GAD65 6.0
LDH-A 6.0
GAD 6.0
DMT 5.9
fracture callus 5.9
imiglucerase 5.9
divalent metal transporter 1 5.9
BIS 5.9
Gli2 5.9
glyceraldehyde 3-phosphate dehydrogenase 5.9
ENA 5.9
HPD 5.8
vesicular GABA transporter 5.8
TAU 5.8
pseudocholinesterase 5.7
gamma-amino butyric acid 5.7
MAM 5.6
alpha1-acid glycoprotein 5.6
microsomal triglyceride transfer protein 5.5
SPS 5.5
PME 5.5
CBD 5.5
troponin C 5.5
SNCA 5.4
metabotropic glutamate receptor 5.4
CD52 5.4
BACE 5.4
5-HT4 5.4
ASD 5.3
IMP 5.3
voltage-gated potassium channel 5.3
VIM 5.3
glial cell line-derived neurotrophic factor 5.2
BAP 5.2
lipoprotein receptor-related protein 5.2
myoglobin 5.2
neurotransmitter receptor 5.1
catechol-O-methyltransferase 5.1
PSE 5.1
PSP 5.1
PEF 5.0
MED 5.0
Elastin 5.0
CIT 5.0
ANF 5.0
LAMP 5.0
LPO 4.9
adenylate kinase 4.9
PNP 4.9
CYP2D6 4.9
Creatine kinase 4.9
DIC 4.9
RyR2 4.8
SCD 4.8
alpha-synuclein 4.8
GDNF 4.8
serotonin receptor 4.8
ataxia telangiectasia mutated 4.8
myosin 4.8
Myosin 4.7
ARS 4.7
c-Rel 4.7
apyrase 4.7
NTR 4.7
perlecan 4.7
calpastatin 4.6
NHE1 4.6
Mucin 4.6
CGI 4.6
MMR 4.6
DJ-1 4.6
PINK1 4.5
strabismus 4.5
DNMT3B 4.5
D2 dopamine receptor 4.5
PTA 4.5
p51 4.5
sex hormone binding globulin 4.5
cardiac muscle 4.5
She 4.4
synuclein 4.4
snRNP 4.4
thyroid stimulating hormone 4.4
CR3 4.3
talin 4.3
DEAD 4.3
huntingtin 4.2
tropomyosin 4.2
BID 4.2
thyroid peroxidase 4.2
SOD2 4.1
more...
Disease
Hypomanic personality 14.9
Parkinsonian crisis 13.3
Clostridium tetani infection 12.3
Vertical gaze palsy 11.9
mild memory disturbance 11.2
NMS 11.1
porcine stress syndrome 11.0
malignant hyperthermia 10.6
Mucinous cystadenocarcinoma 10.2
STHE 10.2
Downbeat nystagmus 9.8
chronic paranoid schizophrenia 9.6
borderline mental retardation 9.5
Autonomic imbalance 9.5
akinesia 9.2
delayed language 9.2
hebephrenia 9.1
Acute asthma 9.0
delusions of persecution 9.0
SCA8 9.0
catatonic schizophrenia 9.0
SPS 8.9
extrapyramidal disorder 8.7
bronchorrhea 8.5
NMS 8.4
abulia 8.3
catalepsy 8.1
Corticobasal degeneration 8.1
eye movement disorder 8.1
fibrothorax 8.0
hereditary sensory neuropathy 8.0
DRD 7.9
myotonia congenita 7.9
mutism 7.9
Rh isoimmunization 7.9
amphetamine abuse 7.8
depressive personality 7.7
FSS 7.7
acalculia 7.7
choreoathetosis 7.7
Bowel perforation 7.6
infantilism 7.6
abnormal involuntary movements 7.5
reflex epilepsy 7.4
echolalia 7.4
laryngospasm 7.3
trismus 7.3
thyroid storm 7.3
Pick's disease 7.2
paramyotonia 7.2
leptomeningitis 7.2
Vidal 7.1
progressive supranuclear palsy 7.1
Herpes simplex encephalitis 7.1
Akathisia 7.0
schizophrenic psychosis 7.0
Kidney Cancer 7.0
Hallervorden-Spatz disease 6.9
parkinsonism 6.9
Tension 6.9
derealization 6.9
sinus tachycardia 6.9
CHAC 6.8
physical dependence 6.7
pseudobulbar palsy 6.7
dyscalculia 6.6
funnel chest 6.6
disorientation 6.5
ACTH deficiency 6.5
dissociative disorder 6.5
agnosia 6.5
inflammatory breast cancer 6.4
kernicterus 6.4
apraxia 6.4
Sutton 6.3
organic brain syndrome 6.3
dyskinesia 6.3
Parkinson's disease 6.3
SIADH 6.3
tetany 6.3
Pulmonary infection 6.3
Binswanger 6.2
ABO incompatibility 6.2
hypersexuality 6.2
Neuromuscular blockade 6.2
phimosis 6.1
thalassemia trait 6.1
gastrointestinal dysfunction 6.1
REM sleep behavior disorder 6.0
torsion dystonia 5.9
Fibrodysplasia ossificans progressiva 5.9
olivopontocerebellar atrophy 5.9
neuromyotonia 5.9
respiratory acidosis 5.9
tardive dyskinesia 5.9
bradyarrhythmia 5.9
cataplexy 5.8
tranquilizers 5.8
alexia 5.8
PME 5.7
stress ulcer 5.7
movement disorder 5.7
aspiration pneumonia 5.7
SSD 5.7
McArdle's disease 5.7
HFA 5.6
paralytic ileus 5.6
delirium 5.6
sensory disturbance 5.6
separation anxiety 5.6
foot drop 5.6
brain atrophy 5.6
GAD 5.6
anemia of chronic disease 5.5
Asperger syndrome 5.5
SPS 5.5
urosepsis 5.5
paranoia 5.5
priapism 5.4
scurvy 5.4
anterograde amnesia 5.4
myoclonus epilepsy 5.4
pernicious anemia 5.4
schizoaffective disorder 5.4
delirium tremens 5.4
powerlessness 5.3
paranoid schizophrenia 5.3
tetanus 5.3
hallucinations 5.3
erectile dysfunction 5.3
myopathy 5.2
Sleep disturbance 5.2
Small cell carcinoma 5.2
emotional instability 5.2
hypernatremia 5.2
Dementia with Lewy bodies 5.2
generalized seizure 5.1
dysphagia 5.1
coma 5.1
fat embolism 5.1
PSP 5.1
neurogenic bladder 5.0
night blindness 5.0
rectal prolapse 5.0
periodic paralysis 5.0
dysautonomia 5.0
disseminated intravascular coagulation 4.9
Syndrome 4.9
osteochondrosis 4.9
Testis 4.8
Testis 4.8
galactorrhea 4.8
ventricular dilatation 4.8
conversion reaction 4.8
esotropia 4.8
diabetic foot ulcers 4.8
perseveration 4.7
THC 4.7
SCD 4.7
bruxism 4.7
more...
Symptom
muscle rigidity 14.9
Extrapyramidal rigidity 13.3
Marked rigidity 13.3
rigors 11.8
Brudzinski's sign 11.4
Retropulsion 11.2
Rest tremor 11.1
Convulsive seizure 10.9
bradykinesia 10.2
Postoperative vomiting 10.0
neurological pain 9.9
muscle stiffness 9.5
peau d'orange 9.3
Extrapyramidal symptoms 9.2
Kernig's sign 9.2
catatonia 8.8
Grimace 8.8
clonus 8.1
tachypnea 8.0
excessive sweating 8.0
auditory hallucination 7.8
tremor 7.8
drooling 7.8
personality change 7.7
motor symptom 7.6
consciousness disturbance 7.5
hypertonia 7.4
muscle cramps 7.4
clumsiness 7.3
bradypnea 7.2
asterixis 7.1
forgetfulness 7.0
myoclonus 7.0
periorbital edema 6.9
ataxic gait 6.7
dark urine 6.7
Stepping 6.6
thirsty 6.5
intention tremor 6.4
spasticity 6.4
prostration 6.3
Tenderness 6.3
spasm 6.2
cerebellar ataxia 6.2
Involuntary Movement 6.2
hypercapnia 6.1
agitation 5.9
dystonia 5.9
blepharospasm 5.9
abnormal gait 5.7
incoordination 5.6
dysarthria 5.6
fasciculation 5.5
limb pain 5.5
twitching 5.4
partial seizure 5.4
chorea 5.4
anesthesia 5.2
pallor 5.1
neurological disability 5.0
orofacial pain 5.0
insomnia 4.9
Stiffness 4.9
leg pain 4.9
joint stiffness 4.8
myalgia 4.8
urinary frequency 4.7
ataxia 4.7
analgesia 4.6
hot flushes 4.6
cyanosis 4.6
chronic constipation 4.5
Sedation 4.5
apathy 4.4
hypotonia 4.3
acute abdomen 4.3
sleepiness 4.2
ophthalmoplegia 4.1
numbness 4.1
nausea 4.0
vomiting 4.0
sneezing 4.0
acute pain 3.9
weakness 3.9
blurred vision 3.8
fever of unknown origin 3.8
syncope 3.7
nausea and vomiting 3.6
exhaustion 3.4
paraparesis 3.4
seizures 3.4
shoulder pain 3.4
dyspnea 3.4
cachexia 3.4
paresis 3.3
dizziness 3.2
hypothermia 3.1
respiratory distress 2.9
hemiplegia 2.9
collapse 2.9
fatigue 2.8
paresthesia 2.6
low back pain 2.6
constipation 2.5
abdominal pain 2.5
lethargy 2.4
chest pain 2.4
flushing 2.2
erythema 2.2
anorexia 2.1
discomfort 2.0
discomfort 1.9
pain 1.9
regurgitation 1.8
diarrhea 1.6
splenomegaly 1.6
Ill 1.4
stigma 1.1
headache 1.1
acidity 1.0
Welt 0.9
angina 0.5
Drug
Hydroxyzine pamoate 13.9
EMD 128130 13.3
Tandospirone citrate 13.3
Vegetamin 13.3
Flexeril 11.5
Mirapex 11.4
Dantrolene sodium 10.9
Abecarnil 10.7
Novafil 10.6
Iopentol 10.2
Iloperidone 9.2
Benserazide 9.1
Lisuride 8.8
Rotigotine 8.2
Paliperidone 8.1
Pramipexole 8.1
Sinemet 8.1
Sinemet 7.9
Fluphenazine 7.9
Iopromide 7.9
Rocuronium 7.7
Carbidopa 7.5
Iodixanol 7.5
Atipamezole 7.5
BOTOX 7.4
Tetanus toxoid 7.4
Sinemet 7.4
Moclobemide 7.3
Medetomidine 7.2
Pramipexole 7.2
Fentanyl 7.1
Thioridazine 6.9
Tubocurarine 6.9
Piracetam 6.4
Ezetimibe 6.0
DEX 6.0
Papaverine 6.0
Reserpine 5.9
Propofol 5.8
Campath 5.3
Campath 5.3
Bupivacaine 5.3
CIA 5.2
Oxaliplatin 5.0
caffeine 4.9
Apomorphine 4.6
Phenytoin 4.5
CTA 4.4
Ringer's solution 4.4
MgSO4 4.3
Simvastatin 4.2
Tacrolimus 4.2
Diurnal 4.1
CDP 3.7
pyridoxal phosphate 3.6
Fluorescein 3.5
Posture 3.4
Alanine 3.4
Rituximab 3.4
Atropine 3.2
PCP 3.0
Fluorescein 3.0
Spectrum 1.9
Ethanol 1.6
CSF 1.5
NADH 1.4
Gel 1.0
MAP 0.9
Monit 0.8
vitamin E 0.8
Nephron 0.7
lysine 0.6
Leaf 0.4
ascorbate 0.4
Cardiovasc -1.2
Enzyme
asparaginyl-tRNA synthetase 8.4
pyridoxal kinase 7.1
creatine kinase 6.8
myosin ATPase 6.7
BIS 5.9
DMT 5.9
NADH-cytochrome b5 reductase 5.8
tryptophan synthase 5.5
AMP deaminase 5.4
SPS 5.2
monoamine oxidase 5.2
glycerol-3-phosphate dehydrogenase 5.1
glycerol-3-phosphate dehydrogenase 5.0
adenylate kinase 4.9
DOPA decarboxylase 4.8
deoxyribonuclease 4.3
deoxyribonuclease 4.3
apyrase 4.3
tyrosine hydroxylase 4.2
PTA 4.1
glyceraldehyde-3-phosphate dehydrogenase 4.0
MPP 4.0
glutamate decarboxylase 3.8
ceruloplasmin 3.5
thyroid peroxidase 3.2
PCP 3.0
cathepsin B 2.8
cholinesterase 2.8
aspartate aminotransferase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
glyceraldehyde-3-phosphate dehydrogenase 2.8
CPT 2.7
hyaluronidase 2.7
glyceraldehyde-3-phosphate dehydrogenase 2.7
lactate dehydrogenase 2.6
pyruvate kinase 2.5
alpha-amylase 2.5
demethylase 2.4
dihydrofolate reductase 2.3
diaphorase 2.3
AST 2.3
hyaluronidase 2.3
AMPK 2.2
choline acetyltransferase 2.2
acid phosphatase 2.2
glyceraldehyde-3-phosphate dehydrogenase 2.2
ribonuclease 2.2
ribonuclease 2.2
thromboplastin 2.2
alanine aminotransferase 2.1
GSK 2.1
MAP 2.0
DNase 1.9
glucose-6-phosphate dehydrogenase 1.9
ATPase 1.9
xanthine oxidase 1.8
CD10 1.6
AMPK 1.3
AMP-activated protein kinase 1.2
P-glycoprotein 1.1
acetylcholinesterase 1.1
RNase 0.9
RNase 0.7
MEK 0.7
phospholipase C 0.7
phosphodiesterase 0.7
superoxide dismutase 0.0
caspase-3 -0.3
focal adhesion kinase -0.6
protein kinase C -0.7
catalase -0.9
protein kinase -1.5
ERK -1.7
mitogen-activated protein kinase -1.7
Compound
Noveril 11.5
Dantrolene sodium 11.1
Flexeril 11.0
1H-indazole-3-carboxylic acid 10.8
Alfentanil 10.3
Biopterin 10.3
Bentazone 10.0
1-benzyl-1,2,3,4-tetrahydroisoquinoline 9.8
9(10H)-anthracenone 9.4
Dantrolene 9.4
Succinylcholine 9.1
Remifentanil 8.7
9(10H)-anthracenone 8.7
CFN 8.5
4-phenyl-1,2,3,6-tetrahydropyridine 8.5
1-Methyl-4-phenylpyridinium 8.4
DCI 8.0
Fluphenazine 7.9
Rocuronium 7.8
MHS 7.7
Veronal 7.7
Thiopental 7.6
Pergolide 7.6
Halothane 7.3
Nitrazepam 7.1
m-cresol 7.1
Pentazocine 7.1
Clonazepam 7.1
Tubocurarine 7.1
Olanzapine 7.0
1,2,3,6-tetrahydropyridine 7.0
1,2,3,6-tetrahydropyridine 7.0
Pentazocine 6.9
Cabergoline 6.9
Picrotoxin 6.9
Picrotoxin 6.9
trimethyllysine 6.8
3,4-Methylenedioxymethamphetamine 6.8
Muscimol 6.8
DMB 6.7
GYKI 52466 6.7
Dexmedetomidine 6.7
Droperidol 6.6
Glycine, 6.6
1,2,3,4-tetrahydroisoquinoline 6.6
Dextromethorphan 6.5
Chlordiazepoxide 6.5
Meperidine 6.4
DMB 6.4
Haloperidol 6.4
Metoclopramide 6.4
Neostigmine 6.3
Glycine, 6.3
Clomipramine 6.2
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 6.2
Haloperidol 6.2
Baclofen 6.2
Risperidone 6.2
Clozapine 6.1
PMP 6.1
Lorazepam 6.1
DEX 6.1
A 71 6.1
L-DOPA 6.0
Venlafaxine 6.0
Papaverine 6.0
Procaine 6.0
Allergan 5.9
DMT 5.9
Paroxetine 5.9
MPTP 5.8
methylformamide 5.8
3,4-dihydroxyphenylalanine 5.8
DMT 5.7
Propofol 5.7
Ketamine 5.7
Dopa 5.7
2,4-dichlorophenyl 5.6
2,4-dichlorophenyl 5.6
Probenecid 5.6
Match 5.6
Clarithromycin 5.5
Tramadol 5.4
Bupivacaine 5.3
SSD 5.3
Uridine 5.2
IMP 5.2
DPH 5.1
BAP 5.1
Tumor Necrosis Factor 5.1
N2O 5.0
Elastin 5.0
QNB 5.0
caffeine 4.9
PSP 4.9
Reserpine 4.9
Isoflurane 4.9
PPi 4.9
Naltrexone 4.9
Valproic acid 4.8
Ryanodine 4.8
NPA 4.8
Creatine 4.8
Bromocriptine 4.8
Valproic acid 4.7
Dopamine 4.6
Diazepam 4.5
Morphine 4.5
DIC 4.5
Bicuculline 4.5
TTS 4.4
MCH 4.4
DAMGO 4.4
Prazosin 4.4
Chlorpromazine 4.4
A 42 4.3
5-HIAA 4.3
DPA 4.3
DPA 4.3
DPA 4.3
DPA 4.3
DPA 4.3
phosphocreatine 4.2
HVA 4.1
MPP 4.1
MPP 4.1
DOPAC 4.0
D-Ala 4.0
neopterin 3.8
PPI 3.8
Cocaine 3.8
PNP 3.8
T10 3.6
coenzyme Q10 3.6
dicarboxylic acid 3.6
GPT 3.6
Starch 3.5
gamma-aminobutyric acid 3.5
Alanine 3.5
CIT 3.4
pyrazine 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
CIT 3.4
benzamide 3.3
piperidine 3.3
more...