Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026837 (muscle rigidity)
 1,077 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To date, there is much evidence confirming that impaired arterial elastic properties have a direct impact on prognosis in patients with chronic renal failure, arterial hypertension, or diabetes mellitus in the general population and in the elderly. At the same time, in most cohort studies the manifestations of coronary heart disease (CHD) constitute about two thirds of developed cardiovascular events (CVE); the value of arterial stiffness after CHD manifestations has not been conclusively ascertained. There are various opinions on the mechanism and pattern of this association. Rigidity of large vessels may be a marker of cardiac artery lesion, on the one hand, and promote deterioration of myocardial ischemia in the presence of coronary atherosclerosis, on the other. This review of literature discusses the pathogenetic and clinical aspects of the impact of stiffness of the great vessels on the development of CVE.
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PMID:[Arterial stiffness as a predictor of cardiovascular events in coronary heart disease]. 2036 7

Rigidity of the arterial wall is a generally accepted marker of cardiovascular diseases. Many studies are designed to investigate arterial rigidity in patients with arterial hypertension, coronary heart disease, and diabetes mellitus. The authors consider pathophysiological mechanisms underlying the enhancement of vascular rigidlity and the respective contributing fiactors, such as extensibility compressibility elasticity modulus, pulse wave propagation velocity, and augmentation index. The main methods for measuring arterial rigidity are described with special reference to non-invasive techniques and fbctors responsible for this condition. Possibilities for medicamental modification of main arteries are discussed
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PMID:[Arterial rigidity, a marker of cardiovascular diseases]. 2256 31