Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026827 (hypotonia)
 5,860 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 71-year-old male patient was operated on in a septic state (tachycardia, hypotonia, fever peaks, disorientation) because of an occluding tumour of the biliary tract. Ketamine was used as the main anaesthetic. Mean arterial pressure increased markedly and diuresis started during the anaesthesia. The inotropic support (dopamine, dobutamine, noradrenaline) could be reduced. Ketamine anaesthesia seemed to have a beneficial haemodynamic effect in septic shock.
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PMID:Ketamine anaesthesia in a patient with septic shock. 163 73

The anaesthetic management of children with neuromuscular diseases giving rise to hypotonia is associated with a variety of problems. Ketamine alone was given by the intravenous or intramuscular route to 32 children with Floppy Infant Syndrome for diagnostic muscle biopsy. The patients aged between three months and 12 yr and weighing 3.2 to 28 kg were studied over three years (1986-1988). The special anaesthetic problems are discussed. The use of ketamine dissociative anaesthesia is reviewed with emphasis on congenital neuromuscular disorders.
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PMID:Ketamine monoanaesthesia for diagnostic muscle biopsy in neuromuscular disorders in infancy and childhood: floppy infant syndrome. 234 Jun 18