Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026827 (hypotonia)
 5,860 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retrospective analysis of cases of acute poisoning with cardiovascular drugs in the period from 1999 to 2002 has been carried out. A total of 72 poisoned patients was treated in the study period in the Lublin Regional Toxicological Centre. The poisoned were mostly women (69%), out of whom 76% were under 30. More than 66% were the cases of mixed poisoning, especially with antidepressant or sedative-hypnotic drugs. Alcohol poisoning was diagnosed in 28% of cases and it was statistically more frequent in men than in women (54.6% and 16.0%, respectively). Cardiovascular drugs were the most frequent cause of suicidal poisoning cases, i.e. beta-blockers were the cause of 40% poisoning cases, ACEI inhibitors--22%, and calcium channel blockers--19%. In 25 cases (in 18 women and 7 men) severe poisoning caused bradyarrhythmia or hypotonia which resulted in the death of 2 patients.
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PMID:[Analysis of cases of acute poisoning with cardiovascular drugs]. 1456 5