Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026825 (
Flaccidity
)
6
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
With a photoelastic method, contact pressure patterns between foot and the floor surface were recorded, occasionally for one minute. The aim of this study is to evaluate the development or maturity of postural control. As a clinical model to be tested, Down syndrome characterized by marked muscular hypotonicity was chosen for quantitative analysis. The following results were obtained; (1) the center of contact pressure is shifted significantly forward in Down syndrome, (2) the position tends to move forward on the left side in both normal and Down syndrome groups, and (3) there was no distinctive laterality of weight loading on either side.
Flaccidity
of ankle joint movements such as abnormal eversion was indicated by a special parameter, which was obtained for the first time by this method.
No To Hattatsu 1991
Sep
PMID:[Photoelastic studies of the position of plantar pressure center and its changes at standing upright: analysis on Down syndrome]. 183 5
Upon admission, 17 of 223 (8%) consecutive patients with severe head injury exhibited a flaccid, wholly unresponsive motor examination. In this study alcoholic intoxication neither caused depressed motor responsiveness in head-injured patients with high serum ethanol levels nor accounted for the motor examination in those exhibiting the flaccid state.
Flaccidity
was attributed principally to impaired ventilation in 4 patients, a major intracranial mass in 12, and a spinal cord injury in 1. Compared to the larger group of head-injured patients, the flaccid patients had a significantly greater incidence of hypercapnia (P less than 0.001), acidosis (P less than 0.01), and both elevated and uncontrollable intracranial pressure (ICP) (P less than 0.001). These findings and the high mortality rate (76%) in this study suggest that the magnitude of respiratory complications and the severity of mechanical brain injury are greater in flaccid patients. The flaccid patients undergoing surgical decompression for major intracranial mass lesions (11 cases) have all died and, although still small in number, this group may represent an important subset with a poor prognosis. Nonetheless, a protocol that encourages rapid radiological and electrophysiological assessment and vigorous surgical and ICP management until the probable cause of flaccidity is identified and treated has benefit. The flaccid state was reversed and a good recovery was attained after the restoration of blood pressure and/or ventilation in 2 patients who appeared to have sustained a very grave head injury. In another patient, absent somatosensory evoked potentials greatly facilitated the diagnosis of a spinal subdural hematoma. This program of prompt diagnosis and intense therapy did not result in a protracted course or undue numbers of severely brain-damaged survivors.
Neurosurgery 1981
Sep
PMID:Flaccidity after head injury: diagnosis, management, and outcome. 730 Oct 64