Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0026764 (multiple myeloma)
36,148 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 2297 proteasome 1369 IgA 1108 Mol 1079 proteasome inhibitor 1066 fused 881 lymphoid 871 cytokine 763 non-Hodgkin's lymphoma 686 IL-6 631 interleukin-6 626 CD38 575 heavy chain 523 p53 520 CD138 512 RPMI 505 SP2 491 interferon 450 IgG3 421 IgE 374 CD34 347 M-protein 344 Bcl-2 332 caspase-3 309 albumin 308 ubiquitin 303 endoplasmic reticulum 287 serum albumin 285 glycoprotein 285 HLA 284 She 281 hemoglobin 279 vascular endothelial growth factor 274 NS-1 274 CD19 271 CD4 270 IFN 263 CD8 261 CD20 259 MRI 250 G-CSF 240 granulocyte colony-stimulating factor 239 serum protein 235 histone deacetylase 235 CD56 233 polypeptide 229 Proteasome 226 tumor necrosis factor 224 STAT3 219 cyclin D1 217 SDS 213 AKT 212 mTOR 201 granulocyte 198 Mcl-1 195 histone 193 CD45 189 p21 187 lactate dehydrogenase 177 collagen 177 alkaline phosphatase 176 MYC 170 RANKL 168 C-reactive protein 162 SCT 158 IL-2 158 tyrosine kinase 155 IgH 155 PI3K 155 ERK 155 thymus 154 FDG 152 insulin 150 beta 2-microglobulin 148 CXCR4 147 erythropoietin 145 peroxidase 144 fibronectin 143 CSF 141 MAPK 140 more...

Disease multiple myeloma 36148 cancer 8996 tumor 5740 lymphoma 4906 leukemia 2469 Hodgkin's disease 1275 plasmacytoma 1262 monoclonal gammopathy of undetermined significance 1101 amyloidosis 1072 chronic lymphocytic leukemia 997 hematologic malignancies 965 anemia 933 gammopathy 875 acute myeloid leukemia 836 non-Hodgkin's lymphoma 805 hypercalcemia 781 chronic lymphocytic leukemia 779 bone disease 758 Leukemia 736 breast cancer 694 macroglobulinemia 649 renal failure 645 tumor growth 601 myelodysplastic syndrome 578 chronic myeloid leukemia 563 thrombocytopenia 555 carcinoma 530 acute lymphoblastic leukemia 515 B-cell lymphoma 486 metastases 479 neutropenia 476 melanoma 469 renal disease 435 peripheral neuropathy 432 proteinuria 426 minimal residual disease 424 osteoporosis 412 graft-versus-host disease 386 prostate cancer 384 plasma cell leukemia 379 extramedullary plasmacytoma 365 dysplasia 361 lung cancer 341 acute leukemia 307 tumor progression 295 rheumatoid arthritis 288 mantle cell lymphoma 286 tumorigenesis 282 lymphoproliferative disorders 281 bone metastases 275 Epstein 270 neuropathy 260 AL amyloidosis 260 renal insufficiency 256 Spleen 248 renal impairment 239 HIV 229 SDS 214 polyneuropathy 212 diabetes 210 plasmacytosis 205 SCID 204 pneumonia 198 Burkitt's lymphoma 190 immunodeficiency 184 adenocarcinoma 181 systemic lupus erythematosus 178 residual disease 168 paraproteinemia 164 hepatocellular carcinoma 162 follicular lymphoma 161 sepsis 159 SCT 158 myelosuppression 154 acute renal failure 153 POEMS syndrome 150 renal cell carcinoma 148 sarcoma 147 hypertension 147 ovarian cancer 146 more...

Symptom pain 602 bone pain 330 fatigue 314 diarrhea 172 nausea 154 weakness 145 dyspnea 144 back pain 126 constipation 105 vomiting 104 splenomegaly 96 anorexia 76 headache 74 collapse 69 hepatosplenomegaly 63 sleepiness 61 abdominal pain 59 hepatomegaly 55 low back pain 46 numbness 44 Ill 43 chest pain 41 cough 40 starvation 39 cachexia 36 paresthesia 34 nausea and vomiting 32 erythema 31 exhaustion 31 dizziness 28 discomfort 27 seizures 26 lethargy 25 discomfort 25 asthenia 25 respiratory distress 24 chills 22 overweight 21 fever of unknown origin 20 hoarseness 18 arthralgia 18 ataxia 17 paresis 17 syncope 16 shortness of breath 16 paraparesis 15 blurred vision 15 polyuria 15 anesthesia 15 myalgia 15 analgesia 14 oliguria 13 night sweats 12 angina 12 tremor 11 HSA 11 pallor 11 exertional dyspnea 11 thinning 11 polydipsia 10 shoulder pain 10 decreased appetite 10 epigastric pain 10 hip pain 10 knee pain 9 consciousness disturbance 9 neck pain 8 tingling 7 cancer pain 7 arm pain 6 agitation 6 livedo 6 leg edema 6 Welt 6 ophthalmoplegia 6 vertigo 6 hypoproteinemia 5 dysarthria 5 muscle cramps 5 flank pain 5 more...

Drug Bortezomib 812 Lenalidomide 344 G-CSF 258 CSF 244 Dermatol 212 IL-2 163 lysine 136 CTX 103 IFN-gamma 96 Zoledronic acid 83 Zoledronic acid 69 Adriamycin 64 MDS 58 CAM 50 Arsenic trioxide 49 CTX 47 CTX 47 Revlimid 46 Rituximab 40 Dial 37 Cardiovasc 36 IL-11 33 MRC 31 ROS 29 PTH 26 Clodronate 25 ABC 24 Filgrastim 24 Prednisone 24 Gel 23 NVP 23 DEX 23 Denosumab 23 ADM 21 Imatinib 20 Asn 20 Filgrastim 20 TRM 19 ascorbate 18 Nephron 18 VCR 18 Nephron 18 MAP 17 APD 16 IFN-beta 15 Leaf 15 Albumin 15 ROC 15 Fludarabine 15 Monit 14 Prednisolone 13 vitamin E 13 CCL 13 p75 13 Gleevec 12 lactose 12 Hypaque 12 Histamine 12 G418 12 VCR 12 Hypaque 12 Campath 11 Vorinostat 11 Aredia 11 Campath 11 DNase I 11 Spectrum 10 Lovastatin 10 Intron A 9 Ibandronate 9 Genasense 9 TAK 9 Intron A 9 Intron A 9 Norplant 9 Meth 9 Tipifarnib 8 Paraffin 8 Spectrum 8 ENT 8 more...

Enzyme proteasome 1373 ERK 495 mitogen-activated protein kinase 439 focal adhesion kinase 262 caspase-3 244 lactate dehydrogenase 199 peroxidase 194 alkaline phosphatase 177 protein kinase 176 trypsin 150 PARP 133 P-glycoprotein 122 MEK 116 CD10 108 caspase-8 103 reverse transcriptase 102 luciferase 100 caspase-9 87 thrombin 79 RNA polymerase 67 BMT 58 protein kinase C 57 neuraminidase 54 papain 54 RNase 50 RNase 50 phosphatidylinositol 3-kinase 49 acid phosphatase 46 APC 45 lysozyme 44 thymidine kinase 44 pepsin 43 topoisomerase 40 topoisomerase 39 IKK 38 ATPase 37 DNA polymerase 37 cdc2 35 MIP 35 collagenase 34 catalase 34 alanine aminotransferase 33 thromboplastin 33 endonuclease 32 glutathione S-transferase 31 MDR 30 urokinase-type plasminogen activator 29 DNA methyltransferase 28 ornithine decarboxylase 27 CD13 27 tissue plasminogen activator 26 ACS 25 phosphoinositide 3-kinase 24 ricin 24 transcriptase 23 superoxide dismutase 23 chymotrypsin 22 plasmin 22 aspartate aminotransferase 21 CDR 21 MDP 21 AMP-activated protein kinase 21 ribonuclease 20 ribonuclease 20 granzyme B 20 beta-galactosidase 20 farnesyltransferase 19 farnesyltransferase 19 CEP 17 aldehyde dehydrogenase 17 CEP 17 calcineurin 17 kinesin 16 cathepsin K 16 adenosine deaminase 15 MAP 15 furin 15 glutamine synthetase 15 DNase 15 phosphodiesterase 15 more...

Compound Clin 4830 Dec 2644 DNA 1828 calcium 602 creatinine 517 Neo 394 sodium 306 sulfate 289 oxygen 238 SDS 229 tyrosine 216 L-PAM 184 L-PAM 182 phosphate 178 PEG 173 His 169 lysine 163 glucose 162 MTT 140 methionine 139 water 139 TNF 138 galactose 135 nitrogen 131 ATP 131 acetate 124 leucine 124 urea 118 iron 114 iodine 113 MPC 109 cysteine 109 Congo red 107 CTX 103 arginine 100 serine 100 retinoic acid 100 bromide 91 Dexamethasone 88 MEK 86 BCNU 83 ammonium 79 alanine 74 threonine 74 Adriamycin 73 PEG 70 boron 69 TBI 69 NH2 67 Phe 62 vitamin D 61 glutamine 56 BCR 55 ADP 53 salt 53 CAM 52 Asp 52 Optimal 49 hydrogen 48 ABL 48 DEAE 45 potassium 45 ethanol 44 DNP 44 benzene 43 Histone 42 GSH 41 ADP 41 ADP 41 GSH 41 GlcNAc 40 MDA 39 Dial 37 isonicotinic acid 37 DBA 36 zinc 36 DBA 36 DBA 36 GalNAc 35 tryptophan 35 more...

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