Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026764 (multiple myeloma)
 36,148 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gastric myeloma is a rare malignant tumor composed of atypical plasma cells and represents, as a rule, only the initial manifestation of widespread myelomatous proliferation. Roentgenographically, it may be indistinguishable from carcinoma of the stomach or it may present as a large intramural mass, often situated along the greater curvature of the stomach. The association of a malignant looking gastric lesion with clinical or radiographic evidence of multiple myeloma should strongly suggest the diagnosis.
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PMID:The radiology corner. Gastric myeloma. 113 Apr

Thirty-three episodes of septicaemia caused by viridans streptococci are reported in 32 adults under treatment for malignant diseases. The underlying diseases were acute leukaemia (17), lymphoma (4), myeloma (1), small cell carcinoma of the bronchus (6), carcinoma of the breast (2) and carcinoma of the stomach (2). Important predisposing factors included severe neutropenia and oral mucositis due to intensive chemotherapeutic regimens. There was a poor response to standard empirical antibiotics and a mortality of 12%. A role for prophylactic penicillin in high risk groups is suggested.
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PMID:Viridans streptococcal bacteraemia in patients with haematological and solid malignancies. 182 67

A man, aged 34, was treated in 1954 for duodenal ulcer by antroduodenectomy followed by X-irradiation to the stomach in a dose of 2,000 rads. Over two decades, he developed several conditions attributable to the previous irradiation, including the physical appearances of premature ageing, shrinkage of the left kidney due to irradiation nephritis, immune deficiency, multiple myeloma of IgA type, and lastly, carcinoma of the stomach. The kidneys, especially the left, the bone marrow and stomach would have been in the field of X-irradiation. These effects of local X-irradiation are discussed in relation to the known effects of total body irradiation in causing decreased longevity in animals and inducing cancer in man.
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PMID:Multiple myeloma and gastric carcinoma. Possible late effects of limited abdominal X-irradiation. 745 10