Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026764 (multiple myeloma)
 36,148 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 49-year-old woman was diagnosed as having multiple myeloma and tuberculosis of the spine (Pott's disease) in 1973. In 1975, she complained of skin nodules in her lower extremities. Biopsy showed that these were amyloid nodules. A bone scan in 1978 showed accumulation of Tc-99m-MDP in the nodules. To our knowledge, this finding has not been previously described.
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PMID:Bone scan in a case of amyloidosis. 735 25

Tuberculous spondylitis is a well-recognized cause of back pain and vertebral collapse due to infection and with must not be overlooked even if it is not the most likely diagnosis. If a patient, particularly one of Asian origin, were to present with a solitary destructive bone lesion, without evidence of myeloma or other malignancy, a trial of anti-tuberculous chemotherapy would be one therapeutic approach, even if there was no evidence of tuberculosis elsewhere. However, failure to biopsy the bone lesion and undertake the appropriate microbiology could lead to other important diagnoses being missed. This is illustrated by the case which we report below.
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PMID:Cryptococcal spondylitis: solitary infective bone lesions are not always tuberculous. 798 98