Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026764 (
multiple myeloma
)
36,148
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Palmoplantar keratoderma
(
PPK
) is a dermatosis that presents as hyperkeratosis of the palms and soles. It may be acquired or heritable. Acquired
PPK
often occurs as a paraneoplastic response as well as a stigma of other dermatoses. We report a rare case of a 72-year-old woman with acquired
PPK
secondary to metastatic uterine adenocarcinoma. We also review other rare cases of cutaneous paraneoplasia secondary to uterine cancer and describe the salient features of acquired
PPK
. Acquired
PPK
most commonly presents as a paraneoplastic response to visceral malignancies that include localized esophageal, pulmonary, urinary/bladder, and gastric carcinomas, as well as
myeloma
. Management of acquired
PPK
includes treatment of the underlying cause. Adjunctive vitamin A analogues have been found to be effective.
...
PMID:Paraneoplastic palmoplantar keratoderma secondary to metastatic uterine adenocarcinoma. 2839 28
