Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
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Query: UMLS:C0025362 (
mental retardation
)
15,878
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This study compared isokinetic arm (elbow flexion and extension) and leg (knee flexion and extension) strength of individuals with Down syndrome (DS), with
mental retardation
without DS (
NDS
), and sedentary young adults with no
mental retardation
(NMR). Eighteen individuals with DS,
NDS
, and NMR (11 men and seven women in each group) performed strength tests on a Cybex 340 isokinetic dynamometer. Parameters measured were peak torque (ft/lb), peak torque percent body weight (%BW), average power (watts), and average power %BW. Subjects with
mental retardation
(ie, DS and
NDS
groups) performed the test on two separate days with best test results chosen for statistical comparisons. The NMR group performed the test once. In all isokinetic strength parameters measured for arm strength, the NMR group demonstrated significantly higher scores than subjects with DS and
NDS
. Subjects with DS and
NDS
displayed similar test results. Similarly, for all the isokinetic strength parameters measured for leg strength, NMR demonstrated significantly higher scores than subjects with DS and
NDS
. Subjects with
NDS
, however, averaged significantly higher test results than subjects with DS for leg strength. The results of this study indicate that both subject populations who were mentally retarded exhibited lower arm and leg strength than the NMR subjects. Additionally, subjects with DS demonstrated inferior leg strength when compared to their peers with
NDS
.
...
PMID:Isokinetic arm and leg strength of adults with Down syndrome: a comparative study. 138 22