Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0025362 (mental retardation)
 15,878 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Sixty-eight patients with childhood autism manifesting with psychoses of different psychopathological structure at the age up to 3 years have been observed. Four psychotic types--catatonic-regressive (19%), polymorphic-regressive (25%), catatonic with mental retardation during psychosis (32%), polymorphic with retardation of mental development during psychosis (24%)--are described. Correlations between a structure of deficit state and these psychoses were determined: 1) development of severe autistic state with pronounced mental development retardation and a lack of speech in the most cases of catatonic-regressive psychoses; 2) autistic state of moderate severity with mental development retardation of different severity and phrase speech formation in a les than half of the patients in polymorphic-regressive psychosis; 3) development of autistic state of moderate severity with mild mental development retardation and phrase speech formation in the majority of the cases in catatonic psychosis; (4) formation of moderately pronounced autistic state in the absence of mental development retardation or its mild degree and phrase speech acquirement after polymorphic psychosis.
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PMID:[Clinical aspects of childhood autism with endogenous manifesting psychosis and mental retardation]. 1500 13