Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0025362 (mental retardation)
 15,878 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Bezoars (BZs) represent the most common foreign bodies of the gastrointestinal tract. Clinical symptoms varying from no symptoms to acute abdominal obstruction. Our goal is to present our experience with a review of the literature. In this study, 23 patients with BZs of the upper gastrointestinal system (GIS) were treated in the surgical department of two generals hospitals in northwest Greece. The size of BZs, localization, predisposing factors, clinical symptoms, morbidity, and mortality were analyzed. Conservative treatment, endoscopic procedures, and surgical treatment were also parameters under consideration. Nineteen patients presenting with phytobezoars and four female patients presented with psychological disorders and mental retardation with trichobezoars. More than one half of them (57%) had previous gastric surgery. Surgical morbidity rate was 28%, whereas the endoscopic morbidity was 11%. Mortality was 4% and 0% for the surgical and endoscopic groups, respectively. The differences in morbidity and mortality rates between the two groups were not statistically significant. BZs are commonly found in the stomach and small intestine, especially in patients who underwent previous gastric surgery. Small bowel obstruction is the most common complication. When uncomplicated, endoscopic or surgical removal of the BZs can be performed easy and effectively.
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PMID:Management of gastrointestinal bezoars: an analysis of 23 cases. 1899 88

An unusual form of bezoar extending from the stomach to the small intestine or beyond has been described as Rapunzel syndrome. Bezoars are concretions in the gastrointestinal tract that increase in size by continuous accumulation of non-absorbable food or fibers. Most bezoars in children are trichobezoars from swallowed hair from the head, dolls, or brushes. Trichobezoars typically cause abdominal pain and nausea, but can also present as an asymptomatic abdominal mass, progressing to abdominal obstruction and perforation. Trichobezoar with Rapunzel syndrome is an uncommon diagnosis in children with less than 40 cases reported. It is predominantly found in emotionally disturbed or mentally retarded youngsters. We present the youngest case of Rapunzel syndrome in the United States, a 5-year-old girl with mental retardation who presented with abdominal pain, vomiting and a non-tender abdominal mass.
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PMID:Rapunzel syndrome: a comprehensive review of an unusual case of trichobezoar. 1962 98