Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0025362 (
mental retardation
)
15,878
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Results of a population-based study of the prevalence of
mental retardation
among 2- to 9-year-old children in Bangladesh were reported. More than 10,000 children were screened for
mental retardation
and other disabilities. All children with positive screening results plus a random sample with negative results were referred for clinical evaluations. The prevalence rates per 1,000 of severe and
mild mental retardation
in this population were 5.9 and 14.4, respectively. As found in studies in developed countries, the prevalence of
mild mental retardation
was strongly and significantly associated with low socioeconomic status, whereas the association for severe mental retardation was relatively weak and not significant.
...
PMID:Socioeconomic status and the prevalence of mental retardation in Bangladesh. 815 87
Linkage analysis of a non-specific form of X linked
mental retardation
(MRX) was performed with 16 polymorphic markers spanning the entire X chromosome in a three generation Italian family, including four male patients with moderate mental retardation. One obligate carrier woman had
mild mental retardation
and another two had normal intelligence. The results indicate tight linkage to DNA markers DXS84 (L754), DXS164 (pERT87-15), and DXS278 (CRI-S232). A maximum lod score of 2.11 at theta = 0.00 was obtained with DXS164 and DXS278. The linked region spanned chromosomal bands Xp21.1-Xp22.3, that is, the same portion of the X chromosome where MRX2 and MRX10-13 have been previously localised.
...
PMID:Mapping of a gene for non-specific X linked mental retardation: evidence for linkage to chromosomal region Xp21.1-Xp22.3. 823 Jan 64
Children diagnosed as
mildly mentally retarded
were examined with respect to performance on Estes's (1965) span-of-apprehension task. Based on their scores on the Simplified Version of the Intellectual Achievement Responsibility scale, we divided subjects into a "learned-helpless" group and a "mastery-oriented" group. Motivational orientation had a significant effect on performance, with the mastery-oriented subjects demonstrating higher detection accuracies than the learned-helpless subjects. These results have implications regarding not only centrally mediated attentional functioning in children with
mental retardation
, but also interpretation of certain previous findings with the span-of-apprehension task.
...
PMID:Motivational orientation and span of apprehension in children with mental retardation. 824 3
Results of a national survey on mental health services for adults with
mild mental retardation
sent to directors of psychological services at community mental health centers was discussed. In general, adults with
mild mental retardation
were less likely to receive the full array of available services. Individuals with
mental retardation
were not frequent consumers of community mental health services and received differential treatment at these Centers. Implications of these findings were discussed.
...
PMID:Service delivery patterns for adults with mild mental retardation at community mental health centers. 827 39
MASA syndrome includes
mental retardation
, adducted thumbs, shuffling gait and aphasia or speech delay. MASA syndrome, X-linked hydrocephalus and X-linked spastic paraplegia have been linked to the same markers on Xq28 and perhaps represent variation in the clinical expression of the same gene or manifestations of different mutant alleles. The present family includes five males in two generations with borderline to
mild mental retardation
(5/5), speech delay (5/5), spastic paraplegia (5/5), adducted thumbs (2/5) and marked hydrocephalus (1/5). Of these males, four were evaluated by MRI or CT scan and all four were determined to have partial to complete agenesis of the corpus callosum (ACC). DNA studies confirm linkage to Xq28 probe St14 (DXS52) with a lod score of 2.86 and no recombination. It is not known if X-linked ACC is linked to the same Xq28 region.
...
PMID:Agenesis of the corpus callosum associated with MASA syndrome. 830 64
The etiology of and suspected risk factors leading to
mild mental retardation
were analyzed in unselected series of 109 Bahraini school children with this condition born between 1967 and 1982. The cause was considered to be prenatal in 38.5% of the children; perinatal (asphyxia and prematurity), in 11.9%; and postnatal, in 7.4%. In 42% the cause was untraceable. Predisposing background factors associated with
mild mental retardation
were compared with characteristics of a matched control group from community schools. An illiterate father, consanguinity, and a relative with
mental retardation
were significantly more common among the sample with
mild mental retardation
. These results are not consistent with the view that mild retardation is predominantly cultural-familial and not pathological in nature.
...
PMID:Etiology of mild mental retardation among Bahraini children: a community-based case control study. 832 72
Adults without
mental retardation
commonly fail to notice nominally obvious aspects of naturalistic scenes (Becklen & Cervone, 1983). We replicated and extended this effect to adults with
mild mental retardation
. Adults with and without retardation viewed a 60-second videotape of an amateur basketball game. They were instructed to press a button whenever the ball was passed. At one point, a woman carrying an open umbrella walked bodily through the ongoing action. Becklen and Cervone found that only 35% of adults without retardation noticed this unexpected event and that noticing was not predicted by task performance prior to the woman's appearance. In the present study noticing rates for subjects without retardation were similar to those reported by Becklen and Cervone and noticing by subjects with
mental retardation
was at least as high. Task performance for subjects with
mental retardation
was significantly lower than that of subjects without retardation, but noticing was not predicted by task performance (prior to the unexpected event) for either group. Results were interpreted in the context of an ecological approach to attention.
...
PMID:Noticing of unexpected events by adults with and without mental retardation. 839 86
Nine and 14-year-old children with
mild mental retardation
and children without
mental retardation
matched for mental and chronological age were first shown a novel category made up of five visual figures. They were then given a recognition test with a set containing the previously presented figures, novel category members, and the category prototype. The relative contribution of prototypical and exemplar-specific information to subjects' performance on the recognition test was evaluated. Results showed that the children without
mental retardation
employed both forms of information in arriving at a recognition decision whereas both of the retarded groups tended to rely only on prototype information. Use of exemplar-specific information was also found to be positively correlated with IQ and, in particular, with measures of short-term memory span.
...
PMID:Development of conceptual knowledge in children with mental retardation. 839 88
Leisure activities were examined for young adults with
mild mental retardation
. Some had disappeared from
mental retardation
services after leaving school; others were in adult day services. Peers without
mental retardation
(comparison subjects) were also included. Various leisure activities were combined using cluster analysis. Some adults with
mental retardation
and some comparison subjects were found in each of the 13 clusters obtained but proportions varied. Leisure patterns were strongly influenced by gender and marital status as well as
mental retardation
, except for one cluster, Socially Isolated, Impoverished, where there were more adults with
mental retardation
, irrespective of gender and marital status.
...
PMID:Patterns of leisure activities of young adults with mild mental retardation. 842 96
Relations among self-reported social skills, teacher ratings of classroom behavior, and direct observations of social interactions among 87 adolescents with
mild mental retardation
were investigated and variables predicting the students' task orientation identified. Three information sources were employed. Results demonstrated that the four domains of social skills were related to the students' task orientation. The regression analysis revealed that students who were characterized by better social skills and fewer occurrences of hyperactivity and behavioral difficulties were viewed by teachers as evidencing more compliant and task-oriented behavior, implying their better ability to benefit from the special curriculum. The three sources of information validated one another and added information to the conceptualization and appraisal of social and academic competence among students with
mental retardation
.
...
PMID:Social skills and classroom behavior among adolescents with mild mental retardation. 851 47
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>