Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0025202 (melanoma)
69,561 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4177
BRAF 3198
Mol 2735
tyrosinase 2176
cytokine 1744
CD8 1731
interferon 1527
F10 1393
p53 1369
IFN 1248
MEK 1135
CD4 970
PD-1 867
interleukin-2 860
HLA 854
nodal 842
MAPK 842
collagen 786
ERK 755
IL-2 746
MEL 745
NRAS 695
caspase-3 643
IFN-gamma 635
AKT 605
tumor necrosis factor 593
Bcl-2 592
fibronectin 588
gp100 578
PD-L1 570
glycoprotein 560
MART-1 548
TNF 525
CTLA-4 517
vascular endothelial growth factor 513
lymphoid 512
MHC 498
PI3K 488
CDKN2A 477
Melan-A 473
NMR 467
S100 456
IL-6 452
HLA-A2 445
colon carcinoma 444
MHC class I 417
p16 416
p21 407
microphthalmia-associated transcription factor 399
MITF 382
MRI 376
vimentin 368
RAF 365
MSH 363
mTOR 358
KIT 350
endoplasmic reticulum 347
matrix metalloproteinase 339
She 330
tyrosine kinase 327
interferon-gamma 325
ERK1 322
ATP 319
major histocompatibility complex 318
IL-10 318
beta-endorphin 317
chemokine 317
osteosarcoma 316
lymphokine 315
p38 315
CDK4 311
E-cadherin 308
fused 297
VEGF 294
PTEN 293
catenin 293
cage 292
MAGE 288
MMP-2 281
Tyrosinase 276
more...
Disease
melanoma 69561
cancer 27569
tumor 26509
metastases 8299
Melanoma 7697
metastatic melanoma 4450
skin cancer 4376
tumor growth 3660
carcinoma 3449
mole 3345
breast cancer 2756
cutaneous melanoma 2482
squamous cell carcinoma 1928
tumor progression 1817
leukemia 1703
mole 1644
lung cancer 1575
lymphoma 1313
adenocarcinoma 1313
primary tumor 1270
sarcoma 1250
tumorigenesis 1179
basal cell carcinoma 1128
renal cell carcinoma 1094
lung carcinoma 959
prostate cancer 908
carcinogenesis 833
colon cancer 785
uveal melanoma 774
colorectal cancer 743
brain metastases 666
non-small cell lung cancer 658
hepatocellular carcinoma 655
dysplastic nevi 646
neuroblastoma 624
ovarian cancer 592
lung metastases 565
lentigo 551
glioma 551
fibrosarcoma 514
glioblastoma 503
Hodgkin's disease 497
multiple myeloma 469
pancreatic cancer 437
benign nevi 410
vitiligo 401
MCF 396
osteosarcoma 385
melanosis 380
renal cancer 375
gastric cancer 367
solid tumor 354
plaque 328
aggressiveness 316
amelanotic melanoma 315
stage IV melanoma 300
psoriasis 299
tumor angiogenesis 296
cervical cancer 292
melanoma in situ 283
liver metastases 283
retinoblastoma 280
SCID 265
epithelial ovarian cancer 262
bladder cancer 259
non-Hodgkin's lymphoma 256
keratosis 253
blue nevus 240
herpes simplex 231
virus infection 224
ocular melanoma 218
Kaposi's sarcoma 216
conjunctiva 215
influenza 214
thrombocytopenia 209
rhabdomyosarcoma 206
Merkel cell carcinoma 205
acute myeloid leukemia 202
infectious diseases 202
diabetes 201
more...
Symptom
pain 421
fatigue 246
nausea 204
erythema 199
diarrhea 193
vomiting 166
headache 146
anesthesia 137
nausea and vomiting 117
weakness 113
anorexia 94
exhaustion 92
abdominal pain 92
dyspnea 84
chills 77
starvation 71
discomfort 61
seizures 59
discomfort 57
cachexia 55
collapse 52
skin damage 50
cough 43
splenomegaly 40
Ill 36
myalgia 35
HSA 35
arthralgia 33
acidity 30
paresthesia 28
constipation 27
cancer pain 25
ENT 24
back pain 24
chest pain 23
ataxia 23
hemoptysis 21
numbness 20
dizziness 20
lethargy 20
thinning 20
hepatomegaly 19
hoarseness 19
blurred vision 19
sleepiness 19
shortness of breath 19
skin irritation 17
epigastric pain 17
analgesia 16
vertigo 14
asthenia 14
overweight 14
bone pain 13
flushing 13
respiratory distress 13
paresis 13
exertional dyspnea 11
tremor 11
dysuria 11
rigors 10
syncope 10
decreased appetite 10
acute abdomen 9
ophthalmoplegia 9
Halo 8
myoclonus 8
oliguria 8
intestinal bleeding 8
anal pain 8
low back pain 8
photophobia 7
agitation 7
paraparesis 7
hyperoxia 7
Scratch 7
otalgia 7
tenesmus 7
colic 7
tinnitus 7
tingling 6
more...
Drug
Dermatol 4662
IL-2 760
IFN-gamma 625
CSF 346
Ipilimumab 246
ROS 217
lysine 199
IFN-beta 142
Retinoic acid 93
Adriamycin 88
ascorbate 84
L-tyrosine 79
CAM 76
Taxol 70
MAP 69
vitamin E 68
BLM 63
CTX 57
Gel 54
p75 52
Cardiovasc 51
Meth 50
Sorafenib 47
uPA 47
Imiquimod 46
NADH 40
Leaf 40
ABC 39
ROC 39
caffeine 39
Paraffin 38
lactose 36
ALA 36
ADR 35
Fotemustine 34
ENT 33
Asn 32
Glutathione 31
Fluorescein 30
Docetaxel 29
Gelatin 29
Imatinib 29
VCR 28
Histamine 28
CCL 28
G418 27
DNase I 27
PDL 26
Fluorescein 26
ETS 25
Monit 24
Kenyan 23
MRC 23
Indomethacin 23
GEO 22
Spectrum 22
VCR 21
TAT 21
CTX 20
Mutagen 19
ADM 19
CTX 19
Gleevec 18
Photofrin 17
Cremophor EL 17
Lovastatin 16
Bortezomib 16
Nitric Oxide 15
niacin 15
RFP 15
EE2 15
G-CSF 15
Ethanol 14
NVP 14
CPT-11 14
Fraction 13
TAK 13
Genasense 13
Taxotere 13
Herceptin 13
more...
Enzyme
tyrosinase 2145
mitogen-activated protein kinase 1960
ERK 1852
MEK 1296
protein kinase 628
caspase-3 525
focal adhesion kinase 479
DCF 468
luciferase 368
protein kinase C 353
PARP 247
lactate dehydrogenase 243
reverse transcriptase 239
proteasome 227
collagenase 202
urokinase-type plasminogen activator 199
trypsin 177
ACS 174
caspase-9 172
catalase 170
tissue plasminogen activator 166
peroxidase 151
superoxide dismutase 133
granzyme B 126
caspase-8 124
thrombin 117
P-glycoprotein 112
cdc2 107
topoisomerase 103
topoisomerase 102
glutathione S-transferase 101
thymidine kinase 98
phenol oxidase 95
plasmin 94
matrix metalloproteinase 2 94
neuraminidase 92
RNA polymerase 92
calcineurin 87
APC 86
phosphoinositide 3-kinase 86
ATPase 85
adenylate cyclase 85
phosphatidylinositol 3-kinase 82
beta-galactosidase 79
alkaline phosphatase 76
phosphodiesterase 70
AMP-activated protein kinase 70
RNase 69
cathepsin B 66
MAP 66
transcriptase 64
gamma-glutamyl transpeptidase 64
RNase 64
MMP 58
GSK 56
AMPK 55
tyrosine hydroxylase 54
CD10 52
ricin 51
transglutaminase 51
ornithine decarboxylase 51
phospholipase C 49
IKK 49
glutathione peroxidase 49
DNA polymerase 48
caspase-1 48
matrix metalloproteinase 9 47
arginase 45
DNA methyltransferase 45
hyaluronidase 45
alanine aminotransferase 45
NQO1 42
enolase 41
AMPK 41
indoleamine 2,3-dioxygenase 40
NO synthase 37
DNase 35
NADPH oxidase 34
firefly luciferase 33
NADPH oxidase 33
more...
Compound
DNA 4942
Dec 4718
Clin 3747
oxygen 1276
MEK 1123
tyrosine 914
water 749
MTT 576
TNF 525
calcium 522
arginine 478
DIC 474
sodium 465
MDA 458
sulfate 426
glucose 383
acetate 382
cAMP 365
retinoic acid 353
PEG 336
phosphate 329
lysine 324
cysteine 322
ATP 322
galactose 301
methionine 300
serine 296
iodine 285
nitric oxide 283
GD3 276
leucine 265
Asp 265
hydrogen 246
Phe 245
iron 244
boron 238
PEG 234
vitamin D 231
nitrogen 231
BCG 226
His 223
Gly 217
Melanin 213
bromide 213
ethanol 208
GSH 199
GSH 199
zinc 192
SDS 190
copper 187
pyrimidine 185
pyrimidine 185
alanine 185
threonine 184
GM3 184
AMP 178
ACS 177
ACS 174
L-DOPA 173
urea 171
methanol 151
Adriamycin 143
alpha-MSH 143
DBA 137
tryptophan 131
BCNU 129
DDP 121
NH2 116
GTP 113
silver 112
GM1 111
GM2 111
salt 107
DBA 104
DBA 104
Interleukin-2 101
hyaluronic acid 101
TNM 100
ADP 99
glutamate 99
more...