Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0025202 (
melanoma
)
69,561
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4177
BRAF
3198
Mol
2735
tyrosinase
2176
cytokine
1744
CD8
1731
interferon
1527
F10
1393
p53
1369
IFN
1248
MEK
1135
CD4
970
PD-1
867
interleukin-2
860
HLA
854
nodal
842
MAPK
842
collagen
786
ERK
755
IL-2
746
MEL
745
NRAS
695
caspase-3
643
IFN-gamma
635
AKT
605
tumor necrosis factor
593
Bcl-2
592
fibronectin
588
gp100
578
PD-L1
570
glycoprotein
560
MART-1
548
TNF
525
CTLA-4
517
vascular endothelial growth factor
513
lymphoid
512
MHC
498
PI3K
488
CDKN2A
477
Melan-A
473
NMR
467
S100
456
IL-6
452
HLA-A2
445
colon carcinoma
444
MHC class I
417
p16
416
p21
407
microphthalmia-associated transcription factor
399
MITF
382
MRI
376
vimentin
368
RAF
365
MSH
363
mTOR
358
KIT
350
endoplasmic reticulum
347
matrix metalloproteinase
339
She
330
tyrosine kinase
327
interferon-gamma
325
ERK1
322
ATP
319
major histocompatibility complex
318
IL-10
318
beta-endorphin
317
chemokine
317
osteosarcoma
316
lymphokine
315
p38
315
CDK4
311
E-cadherin
308
fused
297
VEGF
294
PTEN
293
catenin
293
cage
292
MAGE
288
MMP-2
281
Tyrosinase
276
more...
Disease
melanoma
69561
cancer
27569
tumor
26509
metastases
8299
Melanoma
7697
metastatic melanoma
4450
skin cancer
4376
tumor growth
3660
carcinoma
3449
mole
3345
breast cancer
2756
cutaneous melanoma
2482
squamous cell carcinoma
1928
tumor progression
1817
leukemia
1703
mole
1644
lung cancer
1575
lymphoma
1313
adenocarcinoma
1313
primary tumor
1270
sarcoma
1250
tumorigenesis
1179
basal cell carcinoma
1128
renal cell carcinoma
1094
lung carcinoma
959
prostate cancer
908
carcinogenesis
833
colon cancer
785
uveal melanoma
774
colorectal cancer
743
brain metastases
666
non-small cell lung cancer
658
hepatocellular carcinoma
655
dysplastic nevi
646
neuroblastoma
624
ovarian cancer
592
lung metastases
565
lentigo
551
glioma
551
fibrosarcoma
514
glioblastoma
503
Hodgkin's disease
497
multiple myeloma
469
pancreatic cancer
437
benign nevi
410
vitiligo
401
MCF
396
osteosarcoma
385
melanosis
380
renal cancer
375
gastric cancer
367
solid tumor
354
plaque
328
aggressiveness
316
amelanotic melanoma
315
stage IV melanoma
300
psoriasis
299
tumor angiogenesis
296
cervical cancer
292
melanoma in situ
283
liver metastases
283
retinoblastoma
280
SCID
265
epithelial ovarian cancer
262
bladder cancer
259
non-Hodgkin's lymphoma
256
keratosis
253
blue nevus
240
herpes simplex
231
virus infection
224
ocular melanoma
218
Kaposi's sarcoma
216
conjunctiva
215
influenza
214
thrombocytopenia
209
rhabdomyosarcoma
206
Merkel cell carcinoma
205
acute myeloid leukemia
202
infectious diseases
202
diabetes
201
more...
Symptom
pain
421
fatigue
246
nausea
204
erythema
199
diarrhea
193
vomiting
166
headache
146
anesthesia
137
nausea and vomiting
117
weakness
113
anorexia
94
exhaustion
92
abdominal pain
92
dyspnea
84
chills
77
starvation
71
discomfort
61
seizures
59
discomfort
57
cachexia
55
collapse
52
skin damage
50
cough
43
splenomegaly
40
Ill
36
myalgia
35
HSA
35
arthralgia
33
acidity
30
paresthesia
28
constipation
27
cancer pain
25
ENT
24
back pain
24
chest pain
23
ataxia
23
hemoptysis
21
numbness
20
dizziness
20
lethargy
20
thinning
20
hepatomegaly
19
hoarseness
19
blurred vision
19
sleepiness
19
shortness of breath
19
skin irritation
17
epigastric pain
17
analgesia
16
vertigo
14
asthenia
14
overweight
14
bone pain
13
flushing
13
respiratory distress
13
paresis
13
exertional dyspnea
11
tremor
11
dysuria
11
rigors
10
syncope
10
decreased appetite
10
acute abdomen
9
ophthalmoplegia
9
Halo
8
myoclonus
8
oliguria
8
intestinal bleeding
8
anal pain
8
low back pain
8
photophobia
7
agitation
7
paraparesis
7
hyperoxia
7
Scratch
7
otalgia
7
tenesmus
7
colic
7
tinnitus
7
tingling
6
more...
Drug
Dermatol
4662
IL-2
760
IFN-gamma
625
CSF
346
Ipilimumab
246
ROS
217
lysine
199
IFN-beta
142
Retinoic acid
93
Adriamycin
88
ascorbate
84
L-tyrosine
79
CAM
76
Taxol
70
MAP
69
vitamin E
68
BLM
63
CTX
57
Gel
54
p75
52
Cardiovasc
51
Meth
50
Sorafenib
47
uPA
47
Imiquimod
46
NADH
40
Leaf
40
ABC
39
ROC
39
caffeine
39
Paraffin
38
lactose
36
ALA
36
ADR
35
Fotemustine
34
ENT
33
Asn
32
Glutathione
31
Fluorescein
30
Docetaxel
29
Gelatin
29
Imatinib
29
VCR
28
Histamine
28
CCL
28
G418
27
DNase I
27
PDL
26
Fluorescein
26
ETS
25
Monit
24
Kenyan
23
MRC
23
Indomethacin
23
GEO
22
Spectrum
22
VCR
21
TAT
21
CTX
20
Mutagen
19
ADM
19
CTX
19
Gleevec
18
Photofrin
17
Cremophor EL
17
Lovastatin
16
Bortezomib
16
Nitric Oxide
15
niacin
15
RFP
15
EE2
15
G-CSF
15
Ethanol
14
NVP
14
CPT-11
14
Fraction
13
TAK
13
Genasense
13
Taxotere
13
Herceptin
13
more...
Enzyme
tyrosinase
2145
mitogen-activated protein kinase
1960
ERK
1852
MEK
1296
protein kinase
628
caspase-3
525
focal adhesion kinase
479
DCF
468
luciferase
368
protein kinase C
353
PARP
247
lactate dehydrogenase
243
reverse transcriptase
239
proteasome
227
collagenase
202
urokinase-type plasminogen activator
199
trypsin
177
ACS
174
caspase-9
172
catalase
170
tissue plasminogen activator
166
peroxidase
151
superoxide dismutase
133
granzyme B
126
caspase-8
124
thrombin
117
P-glycoprotein
112
cdc2
107
topoisomerase
103
topoisomerase
102
glutathione S-transferase
101
thymidine kinase
98
phenol oxidase
95
plasmin
94
matrix metalloproteinase 2
94
neuraminidase
92
RNA polymerase
92
calcineurin
87
APC
86
phosphoinositide 3-kinase
86
ATPase
85
adenylate cyclase
85
phosphatidylinositol 3-kinase
82
beta-galactosidase
79
alkaline phosphatase
76
phosphodiesterase
70
AMP-activated protein kinase
70
RNase
69
cathepsin B
66
MAP
66
transcriptase
64
gamma-glutamyl transpeptidase
64
RNase
64
MMP
58
GSK
56
AMPK
55
tyrosine hydroxylase
54
CD10
52
ricin
51
transglutaminase
51
ornithine decarboxylase
51
phospholipase C
49
IKK
49
glutathione peroxidase
49
DNA polymerase
48
caspase-1
48
matrix metalloproteinase 9
47
arginase
45
DNA methyltransferase
45
hyaluronidase
45
alanine aminotransferase
45
NQO1
42
enolase
41
AMPK
41
indoleamine 2,3-dioxygenase
40
NO synthase
37
DNase
35
NADPH oxidase
34
firefly luciferase
33
NADPH oxidase
33
more...
Compound
DNA
4942
Dec
4718
Clin
3747
oxygen
1276
MEK
1123
tyrosine
914
water
749
MTT
576
TNF
525
calcium
522
arginine
478
DIC
474
sodium
465
MDA
458
sulfate
426
glucose
383
acetate
382
cAMP
365
retinoic acid
353
PEG
336
phosphate
329
lysine
324
cysteine
322
ATP
322
galactose
301
methionine
300
serine
296
iodine
285
nitric oxide
283
GD3
276
leucine
265
Asp
265
hydrogen
246
Phe
245
iron
244
boron
238
PEG
234
vitamin D
231
nitrogen
231
BCG
226
His
223
Gly
217
Melanin
213
bromide
213
ethanol
208
GSH
199
GSH
199
zinc
192
SDS
190
copper
187
pyrimidine
185
pyrimidine
185
alanine
185
threonine
184
GM3
184
AMP
178
ACS
177
ACS
174
L-DOPA
173
urea
171
methanol
151
Adriamycin
143
alpha-MSH
143
DBA
137
tryptophan
131
BCNU
129
DDP
121
NH2
116
GTP
113
silver
112
GM1
111
GM2
111
salt
107
DBA
104
DBA
104
Interleukin-2
101
hyaluronic acid
101
TNM
100
ADP
99
glutamate
99
more...