Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0025202 (
melanoma
)
69,561
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
4177
BRAF
3198
Mol
2735
tyrosinase
2176
cytokine
1744
CD8
1731
interferon
1527
F10
1393
p53
1369
IFN
1248
MEK
1135
CD4
970
PD-1
867
interleukin-2
860
HLA
854
MAPK
842
nodal
842
collagen
786
ERK
755
IL-2
746
MEL
745
NRAS
695
caspase-3
643
IFN-gamma
635
AKT
605
tumor necrosis factor
593
Bcl-2
592
fibronectin
588
gp100
578
PD-L1
570
glycoprotein
560
MART-1
548
TNF
525
CTLA-4
517
vascular endothelial growth factor
513
lymphoid
512
MHC
498
PI3K
488
CDKN2A
477
Melan-A
473
more...
Disease
melanoma
69561
cancer
27569
tumor
26509
metastases
8299
Melanoma
7697
metastatic melanoma
4450
skin cancer
4376
tumor growth
3660
carcinoma
3449
mole
3345
breast cancer
2756
cutaneous melanoma
2482
squamous cell carcinoma
1928
tumor progression
1817
leukemia
1703
mole
1644
lung cancer
1575
adenocarcinoma
1313
lymphoma
1313
primary tumor
1270
sarcoma
1250
tumorigenesis
1179
basal cell carcinoma
1128
renal cell carcinoma
1094
lung carcinoma
959
prostate cancer
908
carcinogenesis
833
colon cancer
785
uveal melanoma
774
colorectal cancer
743
brain metastases
666
non-small cell lung cancer
658
hepatocellular carcinoma
655
dysplastic nevi
646
neuroblastoma
624
ovarian cancer
592
lung metastases
565
glioma
551
lentigo
551
fibrosarcoma
514
more...
Symptom
pain
421
fatigue
246
nausea
204
erythema
199
diarrhea
193
vomiting
166
headache
146
anesthesia
137
nausea and vomiting
117
weakness
113
anorexia
94
abdominal pain
92
exhaustion
92
dyspnea
84
chills
77
starvation
71
discomfort
61
seizures
59
discomfort
57
cachexia
55
collapse
52
skin damage
50
cough
43
splenomegaly
40
Ill
36
myalgia
35
HSA
35
arthralgia
33
acidity
30
paresthesia
28
constipation
27
cancer pain
25
ENT
24
back pain
24
chest pain
23
ataxia
23
hemoptysis
21
numbness
20
thinning
20
lethargy
20
more...
Drug
Dermatol
4662
IL-2
760
IFN-gamma
625
CSF
346
Ipilimumab
246
ROS
217
lysine
199
IFN-beta
142
Retinoic acid
93
Adriamycin
88
ascorbate
84
L-tyrosine
79
CAM
76
Taxol
70
MAP
69
vitamin E
68
BLM
63
CTX
57
Gel
54
p75
52
Cardiovasc
51
Meth
50
Sorafenib
47
uPA
47
Imiquimod
46
NADH
40
Leaf
40
ROC
39
caffeine
39
ABC
39
Paraffin
38
ALA
36
lactose
36
ADR
35
Fotemustine
34
ENT
33
Asn
32
Glutathione
31
Fluorescein
30
Imatinib
29
more...
Enzyme
tyrosinase
2145
mitogen-activated protein kinase
1960
ERK
1852
MEK
1296
protein kinase
628
caspase-3
525
focal adhesion kinase
479
DCF
468
luciferase
368
protein kinase C
353
PARP
247
lactate dehydrogenase
243
reverse transcriptase
239
proteasome
227
collagenase
202
urokinase-type plasminogen activator
199
trypsin
177
ACS
174
caspase-9
172
catalase
170
tissue plasminogen activator
166
peroxidase
151
superoxide dismutase
133
granzyme B
126
caspase-8
124
thrombin
117
P-glycoprotein
112
cdc2
107
topoisomerase
103
topoisomerase
102
glutathione S-transferase
101
thymidine kinase
98
phenol oxidase
95
plasmin
94
matrix metalloproteinase 2
94
neuraminidase
92
RNA polymerase
92
calcineurin
87
APC
86
phosphoinositide 3-kinase
86
more...
Compound
DNA
4942
Dec
4718
Clin
3747
oxygen
1276
MEK
1123
tyrosine
914
water
749
MTT
576
TNF
525
calcium
522
arginine
478
DIC
474
sodium
465
MDA
458
sulfate
426
glucose
383
acetate
382
cAMP
365
retinoic acid
353
PEG
336
phosphate
329
lysine
324
ATP
322
cysteine
322
galactose
301
methionine
300
serine
296
iodine
285
nitric oxide
283
GD3
276
leucine
265
Asp
265
hydrogen
246
Phe
245
iron
244
boron
238
PEG
234
vitamin D
231
nitrogen
231
BCG
226
more...