Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0025202 (melanoma)
69,561 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 4177
BRAF 3198
Mol 2735
tyrosinase 2176
cytokine 1744
CD8 1731
interferon 1527
F10 1393
p53 1369
IFN 1248
MEK 1135
CD4 970
PD-1 867
interleukin-2 860
HLA 854
MAPK 842
nodal 842
collagen 786
ERK 755
IL-2 746
MEL 745
NRAS 695
caspase-3 643
IFN-gamma 635
AKT 605
tumor necrosis factor 593
Bcl-2 592
fibronectin 588
gp100 578
PD-L1 570
glycoprotein 560
MART-1 548
TNF 525
CTLA-4 517
vascular endothelial growth factor 513
lymphoid 512
MHC 498
PI3K 488
CDKN2A 477
Melan-A 473
more...
Disease
melanoma 69561
cancer 27569
tumor 26509
metastases 8299
Melanoma 7697
metastatic melanoma 4450
skin cancer 4376
tumor growth 3660
carcinoma 3449
mole 3345
breast cancer 2756
cutaneous melanoma 2482
squamous cell carcinoma 1928
tumor progression 1817
leukemia 1703
mole 1644
lung cancer 1575
adenocarcinoma 1313
lymphoma 1313
primary tumor 1270
sarcoma 1250
tumorigenesis 1179
basal cell carcinoma 1128
renal cell carcinoma 1094
lung carcinoma 959
prostate cancer 908
carcinogenesis 833
colon cancer 785
uveal melanoma 774
colorectal cancer 743
brain metastases 666
non-small cell lung cancer 658
hepatocellular carcinoma 655
dysplastic nevi 646
neuroblastoma 624
ovarian cancer 592
lung metastases 565
glioma 551
lentigo 551
fibrosarcoma 514
more...
Symptom
pain 421
fatigue 246
nausea 204
erythema 199
diarrhea 193
vomiting 166
headache 146
anesthesia 137
nausea and vomiting 117
weakness 113
anorexia 94
abdominal pain 92
exhaustion 92
dyspnea 84
chills 77
starvation 71
discomfort 61
seizures 59
discomfort 57
cachexia 55
collapse 52
skin damage 50
cough 43
splenomegaly 40
Ill 36
myalgia 35
HSA 35
arthralgia 33
acidity 30
paresthesia 28
constipation 27
cancer pain 25
ENT 24
back pain 24
chest pain 23
ataxia 23
hemoptysis 21
numbness 20
thinning 20
lethargy 20
more...
Drug
Dermatol 4662
IL-2 760
IFN-gamma 625
CSF 346
Ipilimumab 246
ROS 217
lysine 199
IFN-beta 142
Retinoic acid 93
Adriamycin 88
ascorbate 84
L-tyrosine 79
CAM 76
Taxol 70
MAP 69
vitamin E 68
BLM 63
CTX 57
Gel 54
p75 52
Cardiovasc 51
Meth 50
Sorafenib 47
uPA 47
Imiquimod 46
NADH 40
Leaf 40
ROC 39
caffeine 39
ABC 39
Paraffin 38
ALA 36
lactose 36
ADR 35
Fotemustine 34
ENT 33
Asn 32
Glutathione 31
Fluorescein 30
Imatinib 29
more...
Enzyme
tyrosinase 2145
mitogen-activated protein kinase 1960
ERK 1852
MEK 1296
protein kinase 628
caspase-3 525
focal adhesion kinase 479
DCF 468
luciferase 368
protein kinase C 353
PARP 247
lactate dehydrogenase 243
reverse transcriptase 239
proteasome 227
collagenase 202
urokinase-type plasminogen activator 199
trypsin 177
ACS 174
caspase-9 172
catalase 170
tissue plasminogen activator 166
peroxidase 151
superoxide dismutase 133
granzyme B 126
caspase-8 124
thrombin 117
P-glycoprotein 112
cdc2 107
topoisomerase 103
topoisomerase 102
glutathione S-transferase 101
thymidine kinase 98
phenol oxidase 95
plasmin 94
matrix metalloproteinase 2 94
neuraminidase 92
RNA polymerase 92
calcineurin 87
APC 86
phosphoinositide 3-kinase 86
more...
Compound
DNA 4942
Dec 4718
Clin 3747
oxygen 1276
MEK 1123
tyrosine 914
water 749
MTT 576
TNF 525
calcium 522
arginine 478
DIC 474
sodium 465
MDA 458
sulfate 426
glucose 383
acetate 382
cAMP 365
retinoic acid 353
PEG 336
phosphate 329
lysine 324
ATP 322
cysteine 322
galactose 301
methionine 300
serine 296
iodine 285
nitric oxide 283
GD3 276
leucine 265
Asp 265
hydrogen 246
Phe 245
iron 244
boron 238
PEG 234
vitamin D 231
nitrogen 231
BCG 226
more...