Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
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Query: UMLS:C0024623 (
gastric cancer
)
36,219
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In two prospective studies, including a total of 1,353 and 1,914 male and female participants, a variety of medical and psychosocial risk factors were assessed by means of personal interviews and observational categories. The incidence of
gastric cancer
was determined for the following study groups: 1) all persons with chronic atrophic gastritis and pernicious anemia who had one to three relatives with a history of
gastric cancer
, 2) persons with a previous operation for gastric ulcer (partial resection) and one to three relatives with
gastric cancer
, and 3) a comparable group without any of these characteristics, serving as a reference. The hypothesis was that significantly more
gastric cancer
was to be expected in groups 1 and 2. A second hypothesis was that interaction between the specific precursors and psychosocial risk factors (chronic
hopelessness
due to withdrawing objects) was useful for the prediction of
gastric cancer
. The results may open new avenues for the prevention of
gastric cancer
via preventive psychotherapy in identified risk groups.
...
PMID:Precursor lesions of the GI tract and psychosocial risk factors for prediction and prevention of gastric cancer. 322 43
Patients with
gastric cancer
considered amenable to a curative surgical procedure on the basis of a conventional preoperative workup (N=98) answered health-related quality-of-life questionnaires and completed a psychiatrist's interview before the intervention. All patients were blinded to the type of surgical procedure that would ultimately be performed; 64 patients eventually received a potentially curative resection, and 34 had palliative surgery. The curative resection group reported significantly more
hopelessness
before the operation than the palliative surgery group. The latter group had more eating dysfunction but minimized their distress to a greater degree than those with a more limited tumor burden. Eating dysfunction,
hopelessness
, and the tendency to minimize distress were independent predictors of prognosis. The findings highlight the need for careful medical interviewing to enhance patient-physician communication about symptoms and signs of malignant diseases.
...
PMID:Relationship of tumor burden and patients' minimization of distress in facing surgery for gastric cancer. 1588 44
Patients with
stomach cancer
are at high risk to experience suicidal ideation. Strain theory of suicide assumes that suicide is preceded by psychological strain. Despite wide international acceptance of the theory, its use with a sample of patients with
stomach cancer
has not previously been reported. The aims were to examine the relationship between psychological strain and suicidal ideation among patients with
stomach cancer
and to determine whether psychopathological factors act as mediators. A cross-sectional study was undertaken involving subjects with no history of mental disorder, and questionnaires were administered by face-to-face interview. Patients who experienced more psychological strain, especially coping strain, are more likely to experience suicidal ideation. The mediation effects of
hopelessness
and psychological distress are significant. Psychological strain,
hopelessness
, and psychological distress may be the vital factors among patients with
stomach cancer
in the suicide-risk assessment interview and for care planning and psychological intervention.
...
PMID:Suicidal Ideation and Psychological Strain Among Patients Diagnosed With Stomach Cancer: The Mediation of Psychopathological Factors. 2832 61