Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024623 (gastric cancer)
 36,219 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cysts were found in 13, ovaries cancer in 53 and uterus myomatosus in 7 females out of 3000 patients with laparoscopy performed. A detailed description is presented in the paper of the laparoscopic changes of the organs in the abdominal cavity, particularly the changes in ovaries and uterus. Only in 33 per cent, changes in the internal genitals of the patients were found on the base of the clinical, laboratory and instrumental examinations whereas with the aid of laparoscopy--in 90 per cent. Carcinosis of peritoneum is most frequently due to ovary cancer whereas liver metastases in 39.71 per cent--due to gastric cancer, and 27.15 per cent--to ovary cancer and relatively rarely--to cancer in the rest of the organs.
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PMID:[Laparoscopy in the diagnosis of diseases of the internal female genitalia]. 15 Jan 32

Hexokinase of the endometrium and gastric mucosa is represented by 5 isoenzymes. The "simplification" of HK isoenzyme spectrum is characteristic of cancer tissue. So, in gastric cancer there is a disappearance of the "slowest" isoenzyme, while in malignant endometrium the "fastest" one was absent. Hexokinase isoenzymes of the serum were identical to those in the tumors in question, that indicates the tumor origin of the body fluid hexokinase. The latter was not observed in normal body fluids. The isoenzymic composition of hexokinase in uterine fibromyoma did not differ from that in normal tissues. If hexokinase appeared in the serum of these patients, its isoenzymic composition was similar to that in the normal uterus. The study on the hexokinase isoenzyme composition may be a valuable adjunct in establishing the differential diagnosis between benign and malignant tumors.
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PMID:[Tumorous origin of the hexokinase in human biological fluids]. 71 18

Some 1220 male and 2102 female cases of malignant neoplasms diagnosed histologically at the Department of Pathology of the Gadjah Mada University in Yogyakarta during the period 1970-73 were analysed. The most frequent tumour sites were among men: nasopharyngeal cancer, 21-8% and skin cancer, 17-6%. Among women the genital cancers were the most frequent with: cervix uteri, 25-7% chorionepithelioma, 3-7%, other uterus, 4-4% and ovary, 7-4%. Breast cancer comprised 17-0%, skin 9-6% and nasopharyngeal cancer 7-9%. Low frequencies were observed in both sexes for cancers of the gastro-intestinal tract and of the respiratory organs; previous reports of the rarity of gastric cancer were confirmed. The observed distribution is discussed in the light of possible biases, and compared with other material on the frequency of cancer from South East Asia.
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PMID:Cancer in Yogyakarta, Indonesia: relative frequencies. 88 80

The accuracy of death certificate diagnoses of cancer in the fixed population of about 100,000 samples in Hiroshima and Nagasaki was determined for the period 1961 approximately 1970 by comparison with autopsy findings. In general, when the death certificate listed cancer as a cause of death it was found at autopsy in a high proportion of cases. However, cancer was not always reported on death certificates, indicating that cancer occurs more frequently than recorded by official mortality statistics. Older persons, persons who die at home, and persons with certain cancers are more likely not to have cancer named on their death certificates. It is estimated that in the 10,749 deaths occurring at home or in hospital, there were 32% more deaths due to cancer than certified on death certificates (3,095 vs. 2,345) and for persons aged 70 or more dying at home it is estimated there were 55% more stomach cancer (269 estimated vs. 174 listed) and 244% more lung cancer (141 estimated vs. 41 listed) than were certified on death certificates. The death certificate is not a good source of information for cancer of the cervix because many cases of this disease reported on death certificates as cancer of the uterus. This practice needs to be taken into account in the use of mortality data for cervical cancer in Japan.
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PMID:Accuracy of diagnosis of cancer among autopsy cases: JNIH--ABCC population for Hiroshima and Nagasaki. 101 79

Mortality of maligant neoplasms of stomach (ICD 151; 84 529 deaths), colon (ICD 153; 13237 deaths), rectum (ICD 154; 13687 deaths), breast (ICD 174; 24400 deaths), and uterus (ICD 180--182; 25308 deaths) in the GDR in the years from 1960 to 1969 is described. There are regional differences of mortality which cannot be explained by demographic and diagnostic factors solely but suggest that there exist real differences of cancer risk. Mortality of stomach cancer is relatively low in the middle regions (Berlin, Frankfurt, Potsdam, Cottbus) and in the region of Erfurt and remakably high in the regions of Schwerin, Neubrandenburg, Gera, Leipzig and Karl-Max-Stadt. Mortality of colonic cancer is highest in Berlin, lowest in Schwerin, Neubrandenburg and Gera. Mortality of rectum cancer shows minor regional differences and another distribution than colonic ancer. Mortality of breast cancer is extremely high in Berlin and very low in Suhl. Mortality of cancer of the uterus reaches high levels in Neubrandenburg and is very low in the region of Karl-Marx-Stadt. In the period 1960--1969, mortality of stomach cancer has decreased whereas mortality of colonic cancer has increased. Mortality of rectum neoplasm remained constant. The time trend of mortality of breast cancer demonstrates regional differences and has increased somewhat in th GDR. Mortality of uterus cancer has slightly decreased. Regional differences and time trends of cancer mortality in the GDR suggest the influence of environmental factors.
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PMID:[On cancer mortality in the German Democratic Republic. Regional differences and time trends of mortality of malignant neoplasms of stomach, colon, rectum, breast, and uterus, 1960--1969]. 115 19

The incidence of primary adenoacanthoma of the stomach is extremely low. In the Sasebo City Hospital, there were only two autopsy cases of adenoacanthoma among 46 cases of gastric cancer during the past four years. The first case was a 45-year-old female with metachronous triple cancers; adenoacanthoma of the stomach, squamous cell carcinoma of the uterus and squamous cell carcinoma of the tongue. Histological examination showed muconodular adenoacarcinoma of the stomach at the time of first operation and adenocanthoma at the time of autopsy. These two cases suggest that adenoacanthomas of the stomach may originate from squamous metaplasia or squamous differentiation of a preexisting glandular carcinoma.
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PMID:Two autopsy cases of primary adenoacanthoma of the stomach. 127 82

In 1901, 20% of autopsied subjects in Trieste were under the age of 30 and 28.8% were over 70. By 1985, only 0.2% were under 30 years of age and 74.5% over 70. An analysis of autopsy reports for 1901 reveals that the primary causes of death at that time were tuberculosis (22.4%), acute pulmonary infections (13.7%) and malignant neoplasms (10.6%). Other pathological conditions found at autopsy were infectious lesions (10.4%), chronic obstructive pulmonary disease (10.2%), arteriosclerosis (only 6.4%), syphilis (4.7%), nutritional deficiency (4.7%), cirrhosis of the liver (4.6%) and acute infections (1.1%). Overall, infectious diseases accounted for 55% of deaths in 1901. In 1985, the cause of death was infection in only 3.7% of cases. During the period analysed, the percentage of deaths from cancer tripled and mean length of survival increased by more than 20 years. In 1901, the neoplasms found most frequently were gastric cancer in males (17.9%) and cancers of the uterus and ovary in females (both 13%). Lung cancer accounted for 7.7% of all deaths from malignant neoplasms in males, and breast cancer for 10.8% of such deaths among females. By 1985, lung cancer accounted for 32.4% of deaths from malignant neoplasms among males and breast cancer for 18% among females. Between 1901 and 1985, there were highly significant increases in the numbers of deaths due to arteriosclerosis and to malignant neoplasms in people of each sex.
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PMID:Changes in underlying causes of death during 85 years of autopsy practice in Trieste. 185 46

Mortality rates in the USSR for the major cancer sites have been computed for the period 1986-88 from official numbers of certified deaths and population estimates provided by the World Health Organization databank, and compared with rates for 26 other European countries. Among males, elevated mortality rates (age-adjusted, world standard) were observed for cancer of the oral cavity and pharynx (6.6/100,000), oesophagus (8.4/100,000) and larynx (6.8/100,000). Mortality from cancer of the stomach (38.4/100,000 males and 16.5/100,000 females, for a total of 87,000 deaths per year) was the highest in Europe. Likewise, overall lung cancer rates among males (61.0/100,000, for over 77,000 deaths per year) were among the highest in Europe, and showed substantial rises over the last 2 decades. Lung cancer mortality in females was comparatively low (6.9/100,000), and increased only moderately. Rates for cancers of the intestine (14.6/100,000 males and 10.6/100,000 females) and of the female breast (12.9/100,000) were comparatively low as compared to most other European countries, and those for prostatic cancer (5.9/100,000) were the lowest registered in Europe. In contrast, mortality for cancer of the uterus (9.7/100,000) was among the highest in Europe, probably due to high mortality from cervical cancer. Priorities for cancer control in the Soviet Union are thus reduction of consumption of tobacco and alcohol, which largely explain the high rates for lung and upper digestive and respiratory sites, improvements in diet composition and food storage to reduce the substantial excess of stomach cancer, and rational screening for cervical cancer.
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PMID:Cancer mortality in the USSR, 1986-88. 193 54

Cancer mortality in relation to radiation dose was evaluated among 4153 women treated with intrauterine radium (226Ra) capsules for benign gynecologic bleeding disorders between 1925 and 1965. Average follow up was 26.5 years (maximum = 59.9 years). Overall, 2763 deaths were observed versus 2687 expected based on U.S. mortality rates [standardized mortality ratio (SMR) = 1.03]. Deaths due to cancer, however, were increased (SMR = 1.30), especially cancers of organs close to the radiation source. For organs receiving greater than 5 Gy, excess mortality of 100 to 110% was noted for cancers of the uterus and bladder 10 or more years following irradiation, while a deficit was seen for cancer of the cervix, one of the few malignancies not previously shown to be caused by ionizing radiation. Part of the excess of uterine cancer, however, may have been due to the underlying gynecologic disorders being treated. Among cancers of organs receiving average or local doses of 1 to 4 Gy, excesses of 30 to 100% were found for leukemia and cancers of the colon and genital organs other than uterus; no excess was seen for rectal or bone cancer. Among organs typically receiving 0.1 to 0.3 Gy, a deficit was recorded for cancers of the liver, gall bladder, and bile ducts combined, death due to stomach cancer occurred at close to the expected rate, a 30% excess was noted for kidney cancer (based on eight deaths), and there was a 60% excess of pancreatic cancer among 10-year survivors, but little evidence of dose-response. Estimates of the excess relative risk per Gray were 0.006 for uterus, 0.4 for other genital organs, 0.5 for colon, 0.2 for bladder, and 1.9 for leukemia. Contrary to findings for other populations treated by pelvic irradiation, a deficit of breast cancer was not observed (SMR = 1.0). Dose to the ovaries (median, 2.3 Gy) may have been insufficient to protect against breast cancer. For organs receiving greater than 1 Gy, cancer mortality remained elevated for more than 30 years, supporting the notion that radiation damage persists for many years after exposure.
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PMID:Cancer mortality following radium treatment for uterine bleeding. 221 30

The incidence of cancer in migrants to New South Wales (NSW) from Italy, Greece, Yugoslavia, Germany, the Netherlands, Poland and USSR has been compared with that in the Australian-born population using data from the NSW Central Cancer Registry for 1972-84. The indirectly age-standardized incidence ratios (SIR) in all seven countries were low for melanoma of skin and high for gastric cancer. Cancers of the colon, oesophagus and lip also tended to have low SIRs. Migrants from Italy, Greece and Yugoslavia had significantly less cancer at all sites than the native-born Australians mainly due to low SIRs for cancers of colon, lung (except Yugoslavian-born men), prostate and, in men, 'head and neck' (excluding nasopharynx). Cancers of breast and testis were relatively less common in migrants from Italy and Yugoslavia. SIRs were high for cancers of bladder (in Italian-born men), liver (in Greek- and Yugoslavian-born men) and nasopharynx (in Greek-born men and Italian-born men and women). Amongst migrants from the four more northerly European countries, ovarian cancer was relatively more common in women from Germany and Poland as was bladder cancer in men, but not women, from Germany and the Netherlands. Cancers which had significantly increased SIRs in one migrant group only were lung (Dutch-born men), cervix uteri and body of uterus (German-born women), gallbladder and bile ducts (Polish-born women), thyroid (Italian-born women), connective and other soft tissue (Russian-born men) and brain (Greek-born men and women computed together). Lymphomas were relatively less common in men born in Yugoslavia.
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PMID:Cancer incidence in European migrants to New South Wales. 226 68


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