Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024591 (malignant hyperthermia)
 2,353 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
RYR1 475
ryanodine receptor 272
Sep 176
RyR1 172
creatine kinase 77
ATP 56
CO2 47
Mol 46
ATPase 41
myoglobin 40
dihydropyridine receptor 37
CPK 30
calmodulin 28
cardiac muscle 26
calcium channel 26
RyR2 26
CACNA1S 25
She 17
MNS 15
endoplasmic reticulum 15
more...
Disease
malignant hyperthermia 2353
myopathy 204
stroke 63
hypertension 45
periodic paralysis 41
muscular dystrophy 34
Duchenne muscular dystrophy 33
depression 33
Central core disease 27
NMS 26
scoliosis 26
acute renal failure 25
renal failure 23
coma 22
DM1 22
respiratory acidosis 21
sepsis 20
prolapse 20
disseminated intravascular coagulation 19
cold 19
more...
Symptom
anesthesia 688
muscle rigidity 124
weakness 76
spasm 46
hypercapnia 39
pain 27
tachypnea 24
myalgia 22
hypothermia 21
hypotonia 20
seizures 18
catatonia 15
fatigue 15
collapse 14
ataxia 14
analgesia 13
cyanosis 13
spasticity 12
muscle stiffness 10
muscle cramps 9
more...
Drug
caffeine 310
Dantrolene sodium 29
Propofol 14
Cardiovasc 10
Ringer's solution 6
NADH 5
Dantrium 5
CaCl2 3
CaCl2 3
CPR 3
Fentanyl 3
Ranitidine 3
CaCl2 3
vitamin E 3
Zmax 2
Azithromycin 2
ABC 2
Nephron 2
Ritanserin 2
ampicillin 2
more...
Enzyme
creatine kinase 128
ATPase 44
phosphorylase 11
monoamine oxidase 8
lactate dehydrogenase 8
aspartate aminotransferase 7
dihydropteridine reductase 7
protein kinase 7
adenylate kinase 6
phospholipase A2 6
acetylcholinesterase 5
CPT 5
endonuclease 5
AMP deaminase 5
alkaline phosphatase 5
calcineurin 4
calcium pump 4
aldolase 4
glutathione peroxidase 4
ATP synthase 4
more...
Compound
calcium 502
caffeine 310
MHS 275
sodium 170
Dec 142
Clin 140
oxygen 113
Dantrolene 110
CO2 86
Halothane 66
DNA 65
ATP 56
potassium 49
water 38
Ryanodine 32
Succinylcholine 31
His 29
glucose 26
Dantrolene sodium 25
Mg2+ 25
more...