Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024591 (malignant hyperthermia)
 2,353 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This is a report on 27 711 thyroidectomies (partial and total) performed in the years 1949 to 1978 at the Empress-Elisabeth-Hospital Vienna. The patients treated comprise cases of simple goitre, recurrences, hyperthyroid and malignant goitres. Typical intra- and postoperative complications, such as air embolism, bleeding, damage to the recurrent nerves, thyrotoxic crisis, hypocalcaemia, disease of the thymus gland and postoperative malignant hyperthermia are discussed. Due to better preoperative medication and surgical technique respectively the frequency of intraoperative complications as well as thyrotoxic crises and recurrent nerve damage went down, thromboembolic complications however, increased corresponding to the increase of the mean age of patients undergoing surgery of their goitre nowadays.
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PMID:[Mortality rate in surgery of goitre. Report on 27711 thyroid operations in the years 1949 to 1978]. 726 41

McArdle disease or type V glycogenosis is a rare metabolic myopathy consisting of muscle loss and weakness. These patients have risks associated with anaesthesia. They can present with hypoglycaemia, rhabdomyolysis, acute renal failure, and electrolyte changes. It has also been associated with a higher incidence of malignant hyperthermia during the anaesthetic procedure. Intermittent compression due to the measurement of non-invasive pressure, postures on the operating table that may cause muscle contractures, or tremor caused by hypothermia or anaesthesia itself, may trigger rhabdomyolysis in these patients. In this article we present our experience in submitting a patient with McArdle's syndrome to general anaesthesia for total thyroidectomy due to multinodular euthyroid goitre.
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PMID:Total thyroidectomys in patient with McArdle's syndrome: Anesthetic management. 3050 83