Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024530 (malaria)
44,886 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 2992
Mol 1817
hemoglobin 1037
cytokine 782
DDT 555
CD4 477
CD8 470
IFN 405
IFN-gamma 382
interferon 349
IL-10 346
TNF 330
surface antigen 324
MSP 305
Mem 295
dihydrofolate reductase 291
Duffy 281
erythrocyte membrane protein 259
tumor necrosis factor 252
RTS 237
CD36 223
ATP 218
IL-4 218
lactate dehydrogenase 206
interferon-gamma 195
NMR 194
glucose-6-phosphate dehydrogenase 191
IgG3 188
IL-6 188
CS protein 187
MSP1 187
thrombospondin 180
gut 177
fused 170
polypeptide 167
HLA 151
endoplasmic reticulum 150
ATPase 149
IL-2 148
TNF-alpha 145
glycoprotein 141
She 136
chemokine 134
ICAM-1 133
ACS 132
cytochrome b 131
kit 123
NANP 122
insulin 118
tumor necrosis factor alpha 118
cryptic 117
ferritin 114
MHC 113
cytochrome P450 110
cysteine protease 110
C-reactive protein 106
histone 104
lipopolysaccharide 103
albumin 101
vascular endothelium 100
major histocompatibility complex 98
Dakar 96
erythroid 94
SDS 93
olfactory 92
membrane-bound 90
TRAP 89
catalase 86
trip 86
Polymerase 86
TLR4 86
nitric oxide synthase 84
SARS 84
NADPH 83
IgE 83
Cytokine 82
lymphoid 82
cytochrome 81
G6PD 78
reductase 77
superoxide dismutase 77
serum albumin 75
inducible nitric oxide synthase 75
GSH 74
CSP 73
membrane protein 71
interleukin-10 69
Duffy antigen 67
haptoglobin 67
thymidylate synthase 66
MHC class I 66
TLR9 66
IgA 65
interferon gamma 65
anonymous 65
mer 65
glutathione reductase 65
serine protease 65
ABO 64
dimeric 63
TCR 62
intercellular adhesion molecule-1 62
transferrin 62
interleukin-6 62
glutathione S-transferase 62
dihydroorotate dehydrogenase 61
CD25 61
telomeric 61
acetylcholinesterase 60
erythropoietin 60
thioredoxin 60
peroxidase 58
glycophorin A 58
collagen 58
IL-8 58
Mil 58
K13 57
DARC 57
transferrin receptor 57
Pseudomonas 57
myosin 57
Glucose-6-phosphate dehydrogenase 56
Burkitt lymphoma 56
CO2 56
epidermal growth factor 56
heme oxygenase-1 55
HLA-DR 55
erythrocyte receptor 55
P450 55
LPS 54
IL-5 54
ACT 54
ADP 54
adhesion molecule 52
Boc 51
proteasome 51
DHFR 51
MHC class II 50
HB3 50
LDH 50
X-linked 49
tRNA 49
CXCL10 49
MyD88 48
San 48
IL-1 48
housekeeping 48
perforin 47
caspase-3 47
interleukin-2 47
IL-17 46
P-glycoprotein 46
GPI 46
CD16) 46
TLR2 46
threonine 46
phosphatase 46
unknown function 46
lectin 46
interleukin-4 45
more...
Disease
malaria 44886
infectious diseases 2360
anemia 2052
HIV 1738
tuberculosis 1531
Plasmodium falciparum malaria 1497
AIDS 1050
dengue 972
West 952
cancer 859
leishmaniasis 694
Plasmodium falciparum infection 629
schistosomiasis 604
malnutrition 456
Infection 436
filariasis 426
coma 381
immunodeficiency 367
Chagas 367
pneumonia 357
influenza 351
thrombocytopenia 350
typhoid 346
yellow fever 332
toxoplasmosis 331
parasitic disease 325
Plasmodium vivax malaria 308
measles 303
thalassemia 291
Cerebral malaria 291
hepatitis B 280
sickle cell disease 280
sepsis 279
G6PD deficiency 273
African trypanosomiasis 258
hypoglycemia 252
diabetes 248
sepsis 246
RTS 238
Rett syndrome 237
fits 233
tumor 220
hepatitis 217
cholera 214
tetanus 206
meningitis 203
iron deficiency 199
leprosy 196
chikungunya 182
Mycobacterium 179
trypanosomiasis 176
acute renal failure 175
hypertension 174
babesiosis 172
cold 172
hookworm 170
syphilis 168
Plasmodium vivax infection 166
renal failure 165
hemolytic anemia 143
Burkitt's lymphoma 143
Tropical Diseases 141
polio 140
worms 139
Infections 136
vaccinia 134
hepatitis C 134
leptospirosis 134
Japanese encephalitis 134
abortion 133
Epstein 132
Parasitemia 128
amebiasis 127
Schistosoma mansoni 127
virus infection 126
encephalitis 126
smallpox 119
hepatitis A 114
SARS 113
depression 113
systemic lupus erythematosus 108
onchocerciasis 106
hemoglobinopathies 103
immunopathology 103
stroke 99
rabies 99
dysentery 98
kala-azar 97
rheumatoid arthritis 97
disseminated intravascular coagulation 93
SDS 93
gastroenteritis 92
diphtheria 91
pulmonary edema 89
plague 88
leukemia 88
viral hepatitis 88
cryptosporidiosis 87
infestation 85
Alzheimer's disease 85
hepatocellular carcinoma 85
rash 80
asthma 80
intestinal parasites 79
encephalopathy 79
pruritus 77
Wuchereria 74
epilepsy 74
GSH 74
Lyme disease 73
bacterial infection 72
typhus 72
cytomegalovirus 70
adult respiratory distress syndrome 69
bacteremia 69
confusion 67
respiratory infection 66
dehydration 66
brucellosis 66
lymphoma 66
ICT 66
retinopathy 64
Adhesion 63
melanoma 62
Echinococcus 62
pertussis 59
scrub typhus 58
hemorrhagic fever 58
zoonosis 58
iron deficiency anemia 57
multiple sclerosis 56
obesity 55
prematurity 55
renal disease 54
atherosclerosis 53
liver infection 52
giardiasis 52
Ebola virus disease 50
Avian malaria 50
cysticercosis 49
Haemophilus 49
preeclampsia 49
proteinuria 49
lupus 49
glomerulonephritis 49
Spleen 49
arthritis 49
bacterial meningitis 48
wasting 48
relapsing fever 48
cardiovascular disease 47
Delhi 45
ischemia 43
breast cancer 43
trachoma 43
heart failure 43
SEM 42
herpes simplex 42
STD 42
DBA 41
more...
Symptom
diarrhea 761
splenomegaly 417
headache 265
vomiting 261
respiratory distress 214
chills 152
seizures 151
pain 129
nausea 127
cough 112
abdominal pain 107
hepatosplenomegaly 95
hepatomegaly 88
fatigue 74
dizziness 73
weakness 67
anorexia 66
myalgia 62
pallor 59
collapse 58
Ill 50
arthralgia 45
starvation 44
fever of unknown origin 40
dyspnea 36
exhaustion 34
hypothermia 30
prostration 27
rigors 27
oliguria 26
anesthesia 24
stigma 22
cerebellar ataxia 22
hunger 21
sore throat 20
tinnitus 20
discomfort 20
tremor 20
discomfort 19
insomnia 18
vertigo 17
sleepiness 17
nausea and vomiting 17
ataxia 17
lethargy 15
agitation 15
erythema 14
overweight 14
chest pain 13
constipation 13
bitter taste 12
stomach pain 12
acidity 11
paresis 11
back pain 10
dark urine 10
asthenia 10
polyuria 9
tachypnea 9
epigastric pain 8
abdominal discomfort 8
cyanosis 8
Hudson 7
shortness of breath 7
night sweats 7
tonic-clonic seizure 7
thinning 7
dental pain 6
apathy 6
analgesia 6
Gastrointestinal symptoms 6
cachexia 6
syncope 6
angina 5
wheezing 5
acute abdomen 5
regurgitation 5
infant diarrhea 5
skin irritation 5
colic 5
flushing 5
leg cramps 4
chorea 4
dysuria 4
low back pain 4
numbness 4
paresthesia 4
catarrh 4
chronic cough 4
body pain 4
excessive sweating 4
memory loss 4
neck stiffness 4
Intermittent fever 4
sneezing 4
hemiplegia 4
hemoptysis 4
Catch 3
anosmia 3
dystonia 3
adenitis 3
abdominal cramps 3
forgetfulness 3
otalgia 3
PUO 3
muscle rigidity 3
consciousness disturbance 3
neuralgia 3
bone pain 3
paraparesis 3
giddiness 3
giddiness 3
rhinorrhea 3
Respiratory symptoms 3
ENT 3
spasm 3
blurred vision 3
torticollis 2
partial seizure 2
muscle stiffness 2
tense 2
hyperemesis gravidarum 2
syncopal episodes 2
hypocapnia 2
hypoproteinemia 2
Bitot's spots 2
clubbing 2
meningism 2
pedal edema 2
despair 2
HSA 2
Mills 2
No adverse effect 2
hypotonia 2
catatonia 2
Kernig's sign 2
left upper quadrant pain 2
Wind 2
rales 2
decreased appetite 2
hyperoxia 2
Psychiatric symptoms 2
sciatica 2
hopelessness 2
acute abdominal pain 2
Organ failure 2
nasal discharge 1
Girdle pain 1
intestinal pain 1
DNA marker 1
hoarseness 1
hypercapnia 1
Visual symptoms 1
intestinal bleeding 1
polydipsia 1
functional recovery 1
Excitability 1
photophobia 1
physical exhaustion 1
tingling 1
more...
Drug
IFN-gamma 375
Kenyan 236
Artesunate 171
Fansidar 166
Fansidar 166
IL-2 150
Primaquine 127
Artemether 117
lysine 102
Atovaquone 101
Dakar 96
Asn 94
Atovaquone 63
ACT 54
CSF 51
Heme 50
Malarone 50
ICI 47
Lumefantrine 41
HCH 41
ascorbate 39
Coartem 38
Doxycycline 38
Lariam 38
Alliance 37
Leaf 33
Lariam 33
Dermatol 33
Glutathione 33
NADH 32
Vitamin A 31
Camp 31
ROS 29
vitamin E 28
Fosmidomycin 27
Quinine, 26
Azithromycin 23
FAD 22
MRC 21
Monit 21
ampicillin 20
nitroglycerin 18
ABC 18
Methylene blue 15
THF 15
Cardiovasc 14
Gel 14
Spectrum 12
lactose 12
ROC 12
Halofantrine hydrochloride 12
Phosphatidylserine 11
EPA 11
AZT 10
citric acid 10
Aloe 10
Glide 10
AZT 10
EPI 10
MAP 10
Bayer 9
Acacia 8
pyridoxal phosphate 8
Albumin 8
Fragment 8
Senna 7
Senna 7
Biopolymers 7
CDP 7
MDM 7
Paludrine 7
G-CSF 7
Dial 6
EE2 6
ENT 6
Trib 6
Spectrum 6
Mutagen 6
Glucose-6-Phosphate 6
CTX 6
Ora 6
Vorinostat 6
Ethanol 6
Award 6
Norplant 5
Fraction 5
caffeine 5
Nephron 5
Angiotensin II 5
Lutalyse 5
DNase I 5
Trimethoprim-sulfamethoxazole 5
Tham 5
Monensin 5
Alanine 5
Nephron 5
Ketoconazole 5
DFP 5
Papain 5
CTX 4
IL-1ra 4
Calcipotriol 4
PCB 4
CTX 4
Silica 4
Mectizan 4
Triclosan 4
Immucillin-G 4
niacin 4
Ezetimibe 4
Android 4
Genasense 4
Fluorescein 4
CPR 4
RFP 4
TAT 4
Vitamin E 4
Nitazoxanide 4
Yellow fever vaccine 4
Vitamin K 4
Halfan 4
Atabrine 4
Indomethacin 4
Colombo 4
BH4 4
p75 4
BCG vaccine 4
Giardiasis 4
NVP 3
Lovastatin 3
Maduramicin 3
Ketotifen 3
Simvastatin 3
CFT 3
Diurnal 3
Bactrim 3
Riboflavin 3
IPM 3
Vitamin B 3
Itraconazole 3
ETS 3
NAG 3
DB289 3
Desferal 3
Hypaque 3
Tinidazole 3
uPA 3
Trypanothione 3
Bortezomib 3
Romidepsin 3
Pentostam 3
NH3 3
Desferal 3
Hypaque 3
Serum albumin 3
ZnO 3
Fluorescein 3
Adenosine deaminase 3
Ranolazine 2
Japanese encephalitis vaccine 2
more...
Enzyme
dihydrofolate reductase 315
lactate dehydrogenase 212
glucose-6-phosphate dehydrogenase 211
protein kinase 170
ATPase 155
dihydropteroate synthase 136
ACS 135
glutathione S-transferase 97
peroxidase 95
trypsin 93
catalase 92
superoxide dismutase 85
mitogen-activated protein kinase 85
ERK 80
acetylcholinesterase 77
alanine aminotransferase 70
thymidylate synthase 68
reverse transcriptase 68
luciferase 66
glutathione reductase 62
dihydroorotate dehydrogenase 60
dihydroorotate dehydrogenase 60
aldolase 56
aspartate aminotransferase 53
proteasome 52
papain 48
neuraminidase 47
P-glycoprotein 46
RNA polymerase 46
glutathione peroxidase 45
alkaline phosphatase 45
NO synthase 45
APC 43
plasmepsin II 41
endonuclease 38
caspase-3 37
chymotrypsin 36
chitinase 35
cytochrome oxidase 34
protein kinase C 34
AOR 33
reductoisomerase 33
PKG 33
topoisomerase 29
thioredoxin reductase 29
granzyme B 28
heme oxygenase 27
phospholipase A2 27
DNA polymerase 26
MIP 26
GSK 26
calcineurin 25
CYP3A4 25
topoisomerase 25
carbonic anhydrase 24
ornithine decarboxylase 23
pyruvate kinase 23
cathepsin D 23
focal adhesion kinase 22
cholinesterase 22
thrombin 22
MDR 21
peroxiredoxin 21
NOS 21
subtilisin 21
adenosine deaminase 20
adenosine deaminase 20
glutamate dehydrogenase 19
glutamate dehydrogenase 19
beta-galactosidase 19
AST 19
complex I 19
phospholipase C 19
glutamate dehydrogenase 19
pyruvate dehydrogenase 18
renin 17
succinate dehydrogenase 17
ATP synthase 17
phosphodiesterase 17
arginase 17
farnesyltransferase 16
xanthine oxidase 16
pyruvate dehydrogenase 15
purine nucleoside phosphorylase 15
caspase-1 15
thromboplastin 15
creatine kinase 15
pyruvate dehydrogenase 15
MEK 14
enolase 14
transcriptase 14
phosphoethanolamine N-methyltransferase 14
protein farnesyltransferase 13
glyceraldehyde-3-phosphate dehydrogenase 13
amorpha-4,11-diene synthase 13
guanylate cyclase 13
PARP 13
ClpP 13
apyrase 13
glyceraldehyde-3-phosphate dehydrogenase 13
acid phosphatase 12
AMPK 12
6-phosphogluconate dehydrogenase 12
6-phosphogluconate dehydrogenase 12
tissue plasminogen activator 12
ACE 12
farnesyltransferase 12
gamma-glutamyl transpeptidase 12
ceruloplasmin 12
CPR 12
SPC 12
HIV-1 protease 11
firefly luciferase 11
pantothenate kinase 11
NADPH oxidase 11
CD13 11
histone acetyltransferase 11
gamma-glutamylcysteine synthetase 10
S-adenosylmethionine decarboxylase 10
xanthine phosphoribosyltransferase 10
glyceraldehyde-3-phosphate dehydrogenase 10
lysozyme 10
MAP 10
RNase 10
deoxyhypusine synthase 10
glyceraldehyde-3-phosphate dehydrogenase 10
deaminase 10
diaphorase 10
spermidine synthase 10
pepsin 10
glyceraldehyde-3-phosphate dehydrogenase 10
Protein 2 9
serine hydroxymethyltransferase 9
RNase 9
lipase 9
chaperonin 9
DNase 9
indoleamine 2,3-dioxygenase 9
hypoxanthine-guanine phosphoribosyltransferase 8
pantetheinase 8
phosphatidylinositol 4-kinase 8
plasmepsin I 8
carboxylesterase 8
NADPH oxidase 8
AMP-activated protein kinase 8
cdc2 8
hexokinase 7
IKK 7
elastase 7
leucine aminopeptidase 7
phosphofructokinase 7
cruzipain 7
choline kinase 7
CD10 7
malate dehydrogenase 7
CPS 7
lysyl-tRNA synthetase 7
ferrochelatase 7
proteinase K 7
TSR 7
more...
Compound
Dec 3366
DNA 2167
Clin 1435
water 1204
iron 696
Chloroquine 593
Chloroquine 593
DDT 567
Artemisinin 562
His 502
oxygen 468
cysteine 369
phosphate 353
TNF 330
glucose 319
calcium 308
sulfate 295
nitric oxide 291
quinoline 230
quinoline 223
ATP 218
sodium 210
serine 205
Mefloquine 194
Mefloquine 193
arginine 181
methanol 175
alanine 175
hydrogen 171
bis(2-chloroethyl) 170
acetate 162
Quinine 158
nitrogen 155
lysine 150
Wellcome 150
Benin 145
salt 139
creatinine 135
ACS 132
zinc 132
ACS 132
Primaquine 127
CO2 121
Pyrimethamine 120
pyrimidine 120
glutamate 118
Hemoglobin 117
pyrimidine 109
urea 107
ethanol 105
leucine 102
SDS 97
methionine 96
GSH 95
GSH 95
DDE 92
galactose 90
threonine 90
tyrosine 90
NADPH 83
NADPH 83
tryptophan 81
silver 77
Ile 77
tryptophan 77
tryptophan 76
tryptophan 76
acridine 75
ICI 75
Phe 74
retinol 73
Amodiaquine 72
hydroxide 68
ethyl acetate 65
aluminum 63
Sulfadoxine 63
Asp 62
BCG 60
ammonium 60
Heme 60
copper 59
acetone 59
Off 58
bromide 58
hexane 58
asparagine 56
chloroform 56
Pac 56
ADP 55
nitrate 55
ADP 54
EDTA 54
ADP 54
EDTA 53
Gly 52
potassium 52
glutamine 51
Halofantrine 51
DHA 50
H2O2 48
BMC 45
DHA 45
cAMP 44
DHA 44
DDD 44
MTT 43
glycerol 43
PEG 42
Optimal 42
DBA 42
DBA 41
DBA 41
NAD 41
acetonitrile 38
isoleucine 38
Triton X-100 38
dichloromethane 38
Doxycycline 38
NADP 37
cGMP 37
proline 36
isoleucine 36
Cysteine 36
iodine 36
ammonia 36
GTP 35
TOF 35
Proguanil 34
6-12 34
phenol 33
N-acetylcysteine 33
MIC 33
benzene 33
NH2 32
NADH 32
NAD 32
aldehyde 32
Panam 32
MVA 32
Deltamethrin 31
acetic acid 31
aldehyde 31
pyridine 31
Vitamin A 31
Mato 30
Hydroxychloroquine 30
COI 29
Permethrin 29
hexose 29
AMP 29
isopentenyl diphosphate 29
Histidine 29
Serine 27
COS 27
GMP 27
pentose 26
pentose 26
DMSO 26
pentose 26
pentose 26
more...