Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The conventional thin blood film method of detecting malaria is a long and tedious procedure, requiring significant technical expertise. In this study, we compared the Quantitative Buffy Coat (QBC) capillary tube method, which requires only minimal technical training, to the thin blood film method, and found it to be not only more rapid but also more sensitive than the thin blood film method in the detection of parasitized red blood cells. We do not suggest that the QBC capillary method can replace the conventional thin blood film method for the detection of malaria since it does not identify or quantitate the parasite species, only that it would serve as a valuable screening test.
Mil Med 1991 May
PMID:Evaluation of the Quantitative Buffy Coat (QBC) method to detect malaria-infected red blood cells. 171 55

Malaria remains a major cause of military casualties in Southeast Asia. The numerous conflicts in the region have been greatly affected by malaria. Besides guerrilla warfare, refugees and other civilian movements across international borders contribute heavily to the continuing problem of multiple drug-resistant malaria. Drug resistance is an increasing problem with few available prophylactic options. The malaria threat to any potential deployment of United States military forces remains unsolved.
Mil Med 1991 Dec
PMID:Malaria as a military factor in Southeast Asia. 178 72

In 1965, an innovative concept in field medicine was launched in the form of a team of highly-trained, multi-disciplined AM-EDD specialists who were assigned to the Walter Reed Army Institute of Research and attached to the 5th Special Forces Group (Abn) while in Vietnam. Officially designated the U.S. Army Special Forces--Walter Reed Army Institute of Research Field Epidemiologic Survey Team (Airborne) (WRAIR-FEST), these personnel took their investigative skills into some of the more remote areas of Vietnam to study disease transmission in militarily hostile circumstances. From 1966-1968, numerous important studies of arthropod-borne diseases, including malaria, scrub typhus, and plague, and of gastrointestinal disorders, medically important arthropods, and cutaneous diseases were successfully conducted.
Mil Med 1991 Feb
PMID:The United States Army Special Forces--Walter Reed Army Institute of Research Field Epidemiological Survey Team (Airborne), 1965-1968. 190 May 98

The countries surrounding the Persian Gulf are remarkable for the variety of infectious and contagious diseases that will affect those deployed to this area. In addition to the common gastrointestinal problems often seen in deployed troops, they will be exposed to such unusual problems as malaria, schistosomiasis, leishmaniasis, and rabies. Medical personnel will need to consider diseases that they have never before treated or diagnosed, and will have to educate their troops regarding control of vectors, avoidance of exposure, and personal hygiene and sanitation. Proper predeployment vaccination, use of appropriate prophylaxis, and use of countermeasures such as insect repellent will keep the spread of disease minimal.
Mil Med 1991 Aug
PMID:Medical aspects of Persian Gulf operations: serious infectious and communicable diseases of the Persian Gulf and Saudi Arabian Peninsula. 153 77

Malaria continues to be a serious disease threat to soldiers deployed in tropical environments. Distinct features of the disease and the host immune response require that malaria occurring in occupational groups be investigated separately from the infection as found in endemic populations. For the first time since the Vietnam War, malaria has been systematically studied in soldiers under combat conditions. In this report we describe characteristics of malaria as experienced by Thai Rangers operating on the Lao-Cambodian border.
Mil Med 1990 Sep
PMID:Occupational malaria in Thai Rangers: epidemiological, clinical and immunological features. 212 Jun 25

Thai soldiers deployed along the Thai-Kampuchean border experience high attack rates of drug-resistant falciparum malaria. Adequate drug prophylaxis has proven difficult with the failure of chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/dapsone. Under some circumstances, mefloquine, doxycycline, and proguanil/sulfamethoxazole can successfully prevent falciparum malaria in Thailand. Decisions regarding chemoprophylaxis drugs in Thailand depend on a complex interaction of effectiveness, compliance, side effects, and long-term usefulness.
Mil Med 1989 Oct
PMID:Malaria prophylaxis during military operations in Thailand. 251 74

The tropical splenomegaly syndrome (TSS) is characterized by massive splenomegaly with hypersplenism, moderate hepatomegaly, and lymphocytic infiltration of the hepatic sinusoids. In previous reports this syndrome has been shown to be a consequence of a disordered immunologic response of the host to malarial infection. Treatment with antimalarial drugs has resulted in a decrease in malarial antibody titers and a reduction in splenic size. We report a child who had TSS associated with cytomegalovirus infection rather than malaria. Our results suggest that TSS may be precipitated by a variety of infections producing chronic antigenic stimulation and perhaps by autoantigenic stimulation as well.
Mil Med 1989 Mar
PMID:Tropical splenomegaly syndrome associated with cytomegalovirus infection. 254 Apr 53

The operational effectiveness of daily doxycycline alone or combined with weekly chloroquine were assessed during deployments of Australian Defence Force personnel to malaria-endemic countries. Doxycycline was given as part of mandated disease prevention measures during United Nations missions to Somalia (900 men for 4 months) and Cambodia (600 men for 12 months over two annual rotations). In Somalia the soldiers were in an area of low endemicity and experienced only three malaria cases (one Plasmodium falciparum, two P. vivax), all occurring after returning to Australia. In Cambodia the level of malaria exposure varied greatly, resulting in eight malaria cases during the entire 2-year mission (two P. falciparum, six P. vivax). Doxycycline was generally well tolerated, with 1.7% (Somalia) and 0.6% (Cambodia) of the men requiring a change of medication to mefloquine due to adverse effects. Doxycycline is an effective chemoprophylactic agent during operational deployments when soldiers truly take it every day.
Mil Med 1995 Sep
PMID:Doxycycline for malaria prophylaxis in Australian soldiers deployed to United Nations missions in Somalia and Cambodia. 747 27

The abundances of three mosquito vectors on Okinawa were determined using New Jersey light traps and compared with data from an identical survey in 1969. The focal distribution of the primary vector of Japanese encephalitis (JE), Culex tritaeniorhynchus Giles, indicates that exposure risks are not uniform throughout the island. The populations of the primary vectors of JE and malaria appear to be declining, resulting in significant changes in the relative abundances of mosquito species. These changes have implications for the current dependent JE immunization program as well as for the possible reintroduction of malaria to Okinawa.
Mil Med 1995 Apr
PMID:Abundance of three mosquito vectors in Okinawa with relevance to disease risk. 761 23

Medical preparation of travelers to overseas locations is an important part of military medical care. We reviewed pre-travel records of patients attending the travel clinic at the National Naval Medical Center (NNMC) and used a post-travel questionnaire to determine the most frequent medical problems associated with international travel. Among 1,416 individuals who received pre-travel care at NNMC, there were 760 (54%) males and 656 (46%) females, the median patient age was 48 years, the most common reason for travel was pleasure, and the median duration of travel was 21 days. The most common destinations were Asia (27%), Africa (15%), Europe (13%), Central America/Caribbean (12%), and South America (11%). The median number of immunizations prescribed was three. Malaria chemoprophylaxis was prescribed to 45%. The average cost of vaccines and medications to medically prepare a traveler was $67. Among 271 (82%) who returned the post-travel questionnaire, the most common illnesses reported were diarrhea (23%) and upper respiratory infections (19%); medical treatment was sought by 9%. Properly informed, military physicians can provide a valuable service at a reasonable cost to reduce the risk of travel-acquired medical problems and illnesses.
Mil Med 1997 Mar
PMID:Epidemiology, preventive services, and illnesses of international travelers. 912 62


1 2 3 4 5 6 Next >>