Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024530 (malaria)
44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper is a review of the interactions between agriculture and vector borne diseases. Rain forest clearing makes possible the development of heliophilous species of anophelines and snails leading to an increase of malaria and schistosomiasis in Africa. But in Asia, clearing is a control method against Anopheles balabacensis, an important malaria vector. Clearing of forest galleries is followed by the disappearance of shore-dwelling tsetse flies. Woodcutters and pioneer farmers are contaminated with arbovirus and leishmaniasis when entering in natural sylvatic foci of these diseases. Management of drinking water reduces guinea worm as well as cholera and other diarrhoeal diseases. More over when piped water becomes available people are no more obliged to store drinking water in containers where vectors use to breed. Reservoirs of dams offer large possibilities for the development of mosquitoes including anophelines vectors of malaria and filariasis and of snails hosts of schistosomiasis. The medical importance of these man-made breeding sites depends of the local epidemiological features of the diseases. Dam spillways provide breeding for blackflies and man-made foci of onchocerciasis have been described in West Africa. Irrigation channels mainly when non cleared of vegetation are good breeding places for anophelines and snails. Irrigated surfaces like rice fields are highly productive in anophelines and other dangerous species of Culicinae. Insecticides used in agriculture, mainly to control cotton and rice pests, have been at the origin of insecticide resistance of several anopheline species. On an other hand, sometimes rice pests control lead to the control of rice field mosquitoes until they become resistant, e.g. for Culex tritaeniorhynchus the vector of Japanese encephalitis in South Korea. Many international organizations have emphasized the role of intersectorial collaboration to control man-made vector borne diseases foci. Good planning of the infrastructures (e.g. twin spillways) and adequate maintenance are essential. Vector control in rice field is a puzzling question. Wet irrigation was a hope but it cannot be done everywhere. Biological control methods have not been proven to be very efficient. Even Bacillus thuringiensis H14 and B. sphaericus have severe limitation. New tools for intersectorial activities should be a goal for scientists imagination.
...
PMID:[Agriculture-health interface in the field of epidemiology of vector-borne diseases and the control of vectors]. 220 69

One of the main reasons for the set-back in the urban malaria control programme is the peculiar biobehaviour of the principal urban malaria vector Anopheles stephensi. Certain relevant facts such as incrimination as the vector of malaria, sibling or biological species, resting habitat, manlanding behaviour, seasonal prevalence, blood meal analysis, longevity, parity status, daily survival and mortality rates of adults, breeding habitats and vertical distribution of larvae of An. stephensi have been discussed. Determination of density of the vector using various parameters and their relation to malaria endemicity in an urban situation have been reviewed. An. stephensi has become resistant to DDT, HCH, malathion and propoxur in many places in India. Hence for control source reduction, use of predators such as fish and biolarvicides such as Bacillus thuringiensis var israelensis H14 and B. sphaericus, personal protection, i.e., use of appropriate clothing, bed nets, indigenous repellents, etc., information, education and communication (IEC) are to be stressed.
...
PMID:Urban malaria vector biology. 929 84

Japanese isolates of Bacillus thuringiensis were screened for larvicidal activity against the mosquito Anopheles stephensi, the urban malaria vector of the Indian subcontinent. Among more than 30 strains identified, larvicidal activity causing > 80% mortality in 72 h was demonstrated for 41/1449 (2.8%) isolates. The majority of strains and isolates (97.2%) exhibited little or no larvicidal activity. Anopheles-active strains belonged to more than 12 H serotypes, especially H3ade (serovar fukuokaensis) and H44 (serovar higo). SDS-PAGE profiles of inclusion proteins showed 4 distinct types among 6 active strains examined. The most active Japanese isolates were H20 strain 89-T-34-14 (LC50 4.4 micrograms/ml) and H44 serovar higo strain 74-E-45-24 (LC50 7.6 micrograms/ml), respectively, 13-fold and 23-fold less active than the international standard H14 serovar israelensis (LC50 0.33 microgram/ml).
...
PMID:Larvicidal toxicity of Japanese Bacillus thuringiensis against the mosquito Anopheles stephensi. 951 45