Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024530 (
malaria
)
44,886
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two ELISAs for estimating
mannan-binding protein
(
MBP
) were constructed and the concentration of
MBP
in plasma was followed in patients undergoing major surgery and in patients having a malarial attack. In both cases increases of
MBP
in the plasma were observed. The relative increase and the kinetics varied from person to person. The concentration of
MBP
increased between 1.5- and three-fold following surgery. In some patients an increase was seen at day 1 whereas in others the increase was not observed until days 3-9. In the
malaria
patients an increased level of
MBP
was maintained during 30 days of treatment with chloroquine. The relative increase in
MBP
was independent of the presurgery or premalaria levels.
...
PMID:The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response. 139 98
