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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although cerebral angiography should be approached with caution in the diagnosis of inflammatory cerebro-vascular disease there are some characteristic angiographic findings which may be helpful for classification and differential diagnosis. The proximal cerebral arteries are favourably affected by basal meningitis and thrombangiitis obliterans with resulting stenoses and occlusions. Whereas those inflammations originating from neighbouring skull structures mostly involve the intracavernous parts of the carotid artery, the tuberculous and mycotic arteritis prefer the supraclinoid carotid siphon. Peripheral vascular changes are found in luetic endangiitis, necrotizing and toxic angiitis and in collagenoses. Simultaneous involvement of the temporal arteries is of great diagnostic importance demonstrating the systemic character of the inflammatory process; in Horton's arteritis it can be a pathognomonic finding. Infectious endocarditis, some mycoses and malaria may lead to embolic occlusion of cerebral vessels. Mycotic aneurysms mostly have a broad base or a fusiform shape and do not prefer the localizations of congenital aneurysms. Angiographically, abscesses, tuberculomas and viral encephalitis may result in circumscribed hypervascularized areas. The characteristic angiographic findings are exemplified and discussed on the basis of 8 cases of inflammatory cerebro-vascular disease (tuberculosis, pneumococcal and unspecific bacterial meningitis, syphilis, mycosis, Takayasu-syndrome, panarteritis nodosa, temporal arteritis).
Fortschr Neurol Psychiatr Grenzgeb 1975 Dec
PMID:[Inflammatory cerebro-vascular disease: angiographic findings and distribution patterns (author's transl)]. 0 27

In order to assist in assessing progress of vector control of filariasis a theoretical model is constructed, using retrospective data on infected persons removed to a vector-free situation. This shows that the decrease of microfilaraemia is not regular, but is gradual for the first 3 years and then more rapid, reaching zero at about 10 years. An estimate is made of the level to which the vector must be reduced before transmission of filariasis ceases, showing that the degree of efficiency required is considerably less than for malaria.
Southeast Asian J Trop Med Public Health 1975 Dec
PMID:Theoretical considerations in the vector control of filariasis. 0 83

This paper describes the characterization of proteinuria in Aotus monkeys infected with quartan malaria (Plasmodium brasilianum), using a micro-disc-electrophoresis system. In the post infection urine samples, increases in total proteinuria, albuminuria and gamma-globulinuria were noted a few weeks after peak parasitaemia. Two new proteins also appeared in the urine of malaria infected animals. These findings are discussed with reference to the belief that the Aotus-P. brasilianum system can be a model for human malaria in renal immunopathology.
Tropenmed Parasitol 1975 Dec
PMID:[Proteinuria in quartan malaria-infected Aotus monkeys]. 5 72

A strain of Plasmodium falciparum, designated Tanzanian I/CDC, from an American tourist returning from Tanzania, was isolated in vitro and in the Aotus monkey. Clinically, the infection showed a late recrudescent pattern of chloroquine resistance. In 2 inoculated Aotus monkeys, the infection recrudesced after a dose of chloroquine (40 mg/kg) curative for sensitive P. falciparum strains in the Aotus monkey. In 4 ,dditional monkeys two primary infections and one of the recrudescent parasitaemias were cured with a 100 mg/kg dose of chloroquine; the second recrudescent parasitaemia was cured with an additional 40 mg/kg dose of chloroquine. The 48 h in-vitro chloroquine-sensitivity test demonstrated that the Tanzanian I/CDC strain had a pattern of chloroquine resistance similar to a reference resistant strain, the Vietnam-Oak Knoll (FVO). These studies reinforce reports which suggest that chloroquine-resistant malaria is being transmitted in East Africa.
Lancet 1979 Dec 01
PMID:Chloroquine-resistant Plasmodium falciparum from East Africa: cultivation and drug sensitivity of the Tanzanian I/CDC strain from an American tourist. 749 Oct 60

Although malaria and hookworm disease appear to be on the decline, another dreaded parasitic disease-schistosomiasis-is on the increase. Presently, the number of infected individuals with schistosomes is estimated to be 250 million, and even though only a small proportion of them become sick and die, schistosomiasis remains a medical problem of great significance. The high incidence of infection of man with Schistosoma mansoni, Schistosoma japonicum or Schistosoma haematobium, as well as the chronic debilitating diseases produced, places these organisms among the world's most important infectious agents. This paper discusses the nature of immunity to schistosomiasis.
J Natl Med Assoc 1979 Dec
PMID:Immunobiology of schistosomiasis. 11 64

Malaria is not a disease of the past. As long as worldwide eradication has not been achieved there is a close connection between countries which export it and those which import it. If the European doctor is presently confronted with a feverish disease which may have been brought in from a tropical area, he should immediately think of malaria and take the necessary measures for treatment. If patients or travelers come into the office and enquire about drugs and preventive measures against malaria, the doctor must choose the correct methods. This is best done by two questions: Where have you come from? and Where are you going? In this way the doctor can obtain ideas on the possibility of resistant strains of parasite in the region in question. Tourists should not forget that a rational and regular chemoprophylaxis is the best protection against serious attacks of malaria.
MMW Munch Med Wochenschr 1979 Dec 14
PMID:[Current information on treatment and prophylaxis of malaria (author's transl)]. 12 May 2

Burkitt's lymphoma occurs mainly in parts of tropical Africa and has attracted the attention of experimental workers due to its epidemiological and clinical features, which indicate a viral etiology and a host immune response to the tumor. As a result of virological studies, Epstein-Barr virus (EBV) DNA has been demonstrated in almost all tested biopsies of African BL. This contrasts to the absence of EBV in all, or almost all, of the non-African Burkitt's lymphoma-like tumors, even though the number of tested tumors in this group is small, and to the lack of EBV in all other types of lymphoma or leukemia. Immunological studies have revealed the presence of antibodies to different EBV-associated antigens in all African patients with Burkitt's lymphoma. However the antibodies are not specific for Burkitt's lymphoma but are found in most adults all over the world, although at lower levels. They cannot therefore serve diagnostic purposes, but they can give prognostic information and occasionally give clues to the mechanisms behind late tumor recurrences, and possibly guide so-called immunotherapy. Burkitt's lymphoma patients contrast to appropriate control groups where some of the persons are anti-EBV seronegative, and this, together with the presence of EBV in Burkitt's lymphoma biopsies and the absence of EBV in other lymphomas, even though the cell type involved may be infectable by EBV in vitro and the tumor may arise in an EBV-carrying person, favors an etiological role in EBV in Burkitt's lymphoma and speaks against the "passenger" hypothesis, according to which EBV is picked up by the Burkitt's lymphoma cell which happens to be particularly suitable for EBV persistence. To explain the geographical distribution, a cofactor, such as certain forms of malaria, has been implied.
Biochim Biophys Acta 1975 Dec 31
PMID:Burkitt's lymphoma - a human tumor model system for immunological studies. 17 35

A biomedical survey was conducted in several areas of Irian Jaya, Indonesia in July 1972 in association with an investigation of reports of a cholera outbreak. Stool specimens, blood smears and sera were collected and examined for evidence of parasitic as well as other infectious diseases. A total of 114 stools were examined and the most commonly found intestinal parasites were Trichuris trichiura (94%), Ascaris lumbricoides (74%), hookworm (58%), Entamoeba coli (15%), Endolimax nana (8%), Entamoeba histolytica (7), Entamoeba hartmanni (4%), Giardia lamblia (3%) and Chilomastix mesnili (3%). A total of 513 blood smears were examined and Wucheria bancrofti microfilariae were detected in 4% and malaria in 4% (Plasmodium falciparum 3%, Plasmodium vivax 2%). The malaria and filarial positive individuals lived in Beeuw, Waigeo and Arar, Sorong. These parasitic infections were not detected in people from Biak City and Sburia, Biak. Sera were collected from 357 persons and significant antibody titers were found for Entamoeba histolytica (4%) Toxoplasma gondii (7%), Influenza A2 Hong Kong 68 (65%), Influenza B Taiwan 68 (78%), Japanese encephalitis virus (87%) and Dengue 1 virus (79%).
Southeast Asian J Trop Med Public Health 1977 Dec
PMID:Biomedical survey in Irian Jaya (West Irian), Indonesia. 20 84

Circulating immune complexes were measured using the Clq-binding test in 185 African mothers and their newborns at delivery. Results were compared to non-pregnant African women, healthy European blood donors and to a group of European mothers and their newborns. Clq-binding activity was increased in African mothers and in non-pregnant African women. Circulating immune complexes rarely occurred in cord blood even when mothers showed a high Clq-binding activity. The levels of immune complexes were unrelated to malaria. Complement components Clq and C3 were lower in the newborns than in the mothers.
Helv Paediatr Acta Suppl 1978 Dec
PMID:Circulating immune complexes in African mothers and their newborns. 21 72

In a random population of 198 pregnant women, detailed haematological determinations were performed at delivery. The prevalence of anaemia (haemoglobin less than 10 g/100 ml) is 20%. Iron deficiency is even more frequent. Malaria is shown to play an important role. Maternal anaemia is also correlated with nutritional status. Primiparae are shown to be at higher risk of anaemia. The effect of maternal anaemia on anthropometric and haematological variables of the newborn are discussed. Mothers with sickle-cell or HbC trait are not at special risk of anaemia.
Helv Paediatr Acta Suppl 1978 Dec
PMID:Maternal anaemia in Abidjan--Its influence on placenta and newborns. 21 75


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