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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tuberculin tests were carried out on 400 adults with established tuberculosis and 200 apparently healthy adults. There was no significant difference in the tuberculin reactivity amongst those tuberculous patients who were clinically in a poor state and the control group. On the other hand the former reacted less than those tuberculous patients whose general physical state was normal and the difference was significant. Overall 23.75% of the tuberculous patients had negative reactions. Women were less reactive than men. The tuberculin allergy decreased with both age and the extent of tuberculous disease. There was no significant variation in the diameter of the skin test as a function of the number of Koch's bacilli. In tuberculous lymphadenopathy we noted a stronger allergy than in tuberculous disease of other parts of the body. There is a positive correlation between the tuberculin reaction and the Serum Albumin level. Associated morbidity (eg infestations, anaemia, malaria, intestinal schistosomiasis and malnutrition) reduce the tuberculin reaction. These observations reduce the diagnostic value of the intra-dermal tuberculin reaction in our environment.
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PMID:[Diagnostic value of the intradermal tuberculin reaction in the adult, in Zaire]. 372 66

Immune response of infants vaccinated under Expanded Programme on Immunization (EPI) was evaluated for measles, poliomyelitis, and tuberculosis in Ifo/Otta area of Ogun State and Badagry area of Lagos State, Nigeria. In the prevaccination evaluation of measles antibody, 59 per cent were protected and 41 per cent were at risk in Ifo/Otta area, while 49 per cent were protected and 51 per cent were at risk in the Badagry area. After measles vaccination, 89 per cent of those evaluated seroconverted and 11 per cent did not in Ifo/Otta area, while in Badagry area, 86 per cent of those evaluated seroconverted and 14 per cent did not. For polio neutralizing antibody evaluated at post-immunization, 91 per cent seroconverted, while 9 per cent did not in Ifo/Otta area, while in Badagry area 66 per cent seroconverted and 34 per cent did not. Tuberculin test was used to evaluate the cellular response to BCG vaccination against tuberculosis. 64 per cent were found protected, while 18 per cent were at risk in both areas examined and 18 per cent dropped out. Using Gomez method to evaluate the nutritional status of the infants, 34 per cent were malnourished in Ifo/Otta area and are mostly immigrants. In Badagry area, 53 per cent were normal while 47 per cent were malnourished and most of the malnourished infants were plagued with diarrhoea, severe cough, high fever or malaria infection. Most of the malnourished in the two areas screened were between 9 and 18 months of age, which is the crucial period in the growing stage of the children.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Evaluation of immune response in infants with different nutritional status: vaccinated against tuberculosis, measles and poliomyelitis. 785 39