Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The Essential National Health Research (ENHR) strategy involves communities, researchers, and policy and decision makers in setting research priorities and finding solutions to health problems. Nongovernmental organizations (NGOs) and young researchers in Bangladesh have responded to the ENHR movement. Two leading NGOs, which have adopted the ENHR strategy, are the Bangladesh Rural Advancement Committee and the International Centre for Diarrhoeal Diseases and Research, Bangladesh. ENHR-inspired research includes examination of drug addicts in Rajshahi, rapid diagnosis of malaria, and determinants of maternal and child health care in urban slums. The ENHR secretariat in Bangladesh intends to disseminate findings of ENHR-inspired research through seminars and workshops with academics, administrators, planners, and policy makers. IDRC supports the research of young health professionals through ENHR's Research Award Scheme. The ENHR Working Group is now reviewing 20 research proposals. Bangladesh has a 15-member ENHR Working Group and a 21-member ENHR National Forum, both of which include representatives from NGOs and government. The Working Group has developed a 10-year prospective plan, an inventory of selected research institutions and investigators, and a list of research priorities. It has appointed a national ENHR coordinator. The ENHR strategy is creating a national capability for research and is establishing a link between research and policy formulation.
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PMID:Targeting basic health problems. 1228 83

The primary health care program in the Philippines today officially includes only the control of parasites which cause malaria and schistomiasis. Dr. Solon suggests that equal emphasis should be given to the control of all types of parasites. This paper presents excerpts from an interview with Dr. Solon. He expresses his opinion that in the past 20 years infant mortality has decreased markedly. In 1985, it was reduced to 58/1000 live births. He attributes this to a political will to support the health ministry in the implementation of its programs. The efforts to implement primary health care (PHC) has resulted in receiving the Kawaski Award given by Japan and the World Health Organization (WHO) to a country successfully implementing PHC. JOICFP has demonstrated the approaches used in the integration of family planning, nutrition and parasite control. Dr. Solon hopes that the integrated project would pave the way for the control of parasites other than schistostomiasis and malariasis. Less attention has been paid to the control of helminths such as ascaris, bookworm, trichuris t. and roundworm, which are common in the Philippines. Worms may cause deadly diseases such as pneumonia and bronchitis. JOICFP has shown that in several project areas in the country, use of the right personnel, equipment and anthelmintics can result in controlling these parasites.
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PMID:Parasites of all types must be controlled. 1231 90

William Collins, Ph.D., received his B.S. and M.Sc. degrees in entomology from Michigan State University. He completed his Ph.D. at Rutgers University in two years, just before being inducted into the Army to serve in the Korean War. He was assigned to Fort Detrick at the Biological Warfare Research Laboratories and after three years returned to Rutgers as an extension entomologist. He accepted a position in 1959 with the U.S. Public Health Service, with which he has worked for the last 50 years. In 1963, the Public Health Service laboratory moved to Atlanta and Dr. Collins' group began working with non-human primates following the discovery that monkey malarias were transmissible to humans. Parasites from monkeys or apes isolated in Asia, South America, and Africa were sent to the laboratory in Chamblee, Georgia, where they were adapted and transmitted to laboratory-maintained primates and their life cycles described and characterized. Transmissions to human volunteers were also attempted. In 1973, the laboratory operation was transferred to the CDC, and the emphasis changed from the study of monkey malaria in monkeys to that of human malaria in monkeys. During the last 25 to 30 years, different isolates of human malaria parasites have been adapted to New World monkeys to characterize the isolates for the development and testing of drugs and vaccines. Dr. Collins' task has been to identify and choose the best combination of vector-parasite-host combinations for testing each vaccine candidate. He has co-authored more than 450 manuscripts and has been awarded the U.S. Public Health Service Superior Service Award, The Joseph A. LaPrince Medal for Malariology from the American Society of Tropical Medicine and Hygiene, The Distinguished Service Award of the Department of Health and Human Services, the William Watson Medal of Excellence from the Centers for Disease Control and Prevention, and the Hoogstraal Medal from the American Committee of Medical Entomology.
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PMID:Interview with the expert: William E. Collins, Ph.D. Interviewed by Vicki Glaser. 1983 79

This year's Lasker DeBakey Clinical Research Award goes to Youyou Tu for the discovery of artemisinin and its use in the treatment of malaria--a medical advance that has saved millions of lives across the globe, especially in the developing world.
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PMID:Artemisinin: discovery from the Chinese herbal garden. 2190 97

The 2011 Lasker~DeBakey Clinical Medical Research Award honors the Chinese scientist Tu Youyou who discovered artemisinin and its utility for treating malaria. A therapy based on artemisinin has saved millions of lives across the globe, especially in the developing world. Meanwhile, artemisinin and its derivatives, especially for artemether and artesunate, are showing promising preventive efficacies as high as 65-97% administrated with multiple doses at 6 mg/kg body weight by 1- or 2-week intervals for preventing schistosomiasis japonica during epidemic seasons used in China for more than one decade. So, we would like to say, to our excitement, artemisinin and its derivatives are the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
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PMID:Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control. 2203 38

I was recently awarded the Alice and C. C. Wang Award in Molecular Parasitology for my contributions to antimalarial drug development, including laying the groundbreaking work that has led to two new molecular methods for curing malaria. This award means a great deal to me because I have spent much of my scientific career feeling like an imposter-one with the wrong sort of background and poor credentials. I am grateful for the recognition, and I am beginning to recognize that having an atypical background can be an advantage because it gives you a different perspective on a challenge. More generally, diversity in educational and cultural backgrounds is important because it can stimulate new ways of thinking and discovery.
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PMID:An improbable journey: Creativity helped me make the transition from art to curing malaria. 3040 50