Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Five cases of airport malaria were observed in Geneva in the summer of 1989. All the patients lived within 2 km of Geneva-Cointrin International Airport. They were hospitalized between July 14 and August 2 for high fever. None had received a recent blood transfusion, an i.v. injection or traveled to a tropical country, except for one, a former pilot, whose last brief visit had been a year earlier. High minimum temperatures between July 6 and 10 in all likelihood allowed the survival of infected anopheles introduced by an aircraft. P. falciparum was identified in the blood smears of all the patients. Four had one or more symptoms of serious malaria and received intravenous treatment. In the fifth patient, treatment with cotrimoxazole for suspected acute pyelonephritis made diagnosis particularly difficult because the malaria infection was partially controlled by the antibiotic therapy. The time necessary for diagnosis of malaria varied from 5 to 31 days in the 5 cases. Airport malaria has been observed over the past twenty years in Europe, particularly in the summer, and is often serious because of late diagnosis and the type of plasmodium most frequently involved, P. falciparum. This diagnosis should be considered in patients with high fever of unknown origin, even when they have not travelled to an endemic zone.
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PMID:[Airport malaria: mini-epidemic in Switzerland]. 221 43

We report a case of Plasmodium vivax malaria in a patient who had not visited an endemic area. The ways in which malaria can be transmitted in non-endemic areas are discussed. By the elimination of other possibilities, the diagnosis of airport malaria was made. Airport malaria is a rare and often initially overlooked diagnosis. Since 1969, some 89 cases of airport malaria have been reported.
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PMID:Airport malaria: report of a case and a brief review of the literature. 1268 93

The newly obtained data supplemented our knowledge about risk for travellers, tourists and natives of Europe connected with malaria, leishmaniasis and other tropical diseases. It was discovered that healthy carriers of Epstein-Barr virus (nearly 90% of human population) have a great risk to get chronic Burkitt lymphoma disease as a result of Plasmodium falciparum (tropical malaria agent) infection. HIV carriers being occasionally in contact with visceral leishmaniasis vectors (sand-flies infected on dogs in the Mediterranean area) not only got a heavy form of disease but became a source of infection for healthy people. Airport malaria and outbreaks of dengue fever sometimes were (and are) connected with an import of infective Anopheles or Aedes mosquitoes. The high risk of borreliosis and ehrlichiosis infection exists in the forested European areas along the highways, where picnics and other types of recreation of travellers and tourists are typical and where the anthropogenically changed Ixodes ticks subpopulations are distributed. Such physiologically changed part of tick population is more aggressive and "changed ticks" more often are vectors of one, two or even more agent species simultaneously.
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PMID:Bloodsucking arthropods: the danger for travellers and hazard of vector travelling. 1688 48

Airport malaria is a particular form of autochthonous malaria: it happens when the Plasmodium infected Anopheles genus mosquito travels from an endemic area to a malaria free airport. Since 1969, 30 cases of airport malaria have been reported in France, 2 during summer 2008. The severity of airport malaria is explained by the frequency of Plasmodium falciparum infecting non immune individuals and an often important diagnosis delay. It is a compulsory notification disease in France. The International Health Regulations (IHR) require states to check that airplanes coming from malaria or arboviral endemic area are systematically disinsected. Vector control measures have to be implemented within a distance of at least 400 meters around the perimeter of airports in malaria or arboviral endemic areas. In France, this measure applies to all airports of French overseas territories, except for the island of Saint-Pierre and Miquelon.
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PMID:[Airport malaria]. 1928 31