Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the framework of the smallpox eradication worldwide programme, WHO, the Ethiopian, and the French governments signed a cooperation agreement by which the French Army Medical Service, based in the French Afars and Issas Territory (TFAI), was designated to carry out an immunization campaign in the ethiopian districts along the border with TFAI. With the every-day collaboration of the ethiopian governmental and traditional authorities, 44,000 people were immunized by the medical and paramedical personnel of 5 "ground teams" with heavy equipment and all-track vehicles and 1 "air-team" with helicopteres. In the same time (7 Feb. - 8 March 1974), the teams collected epidemiological informations on five selected tropical diseases: tuberculosis, malaria, bilharziosis, cholera, small-pox; a team from the TFAI Hygiene and Epidemiological Service investigated thoroughly the Kalo area. The ethiopian border districts are under-equiped with medical and hygiene facilities, and the population is used to go to the TFAI dispensaries and hospitals. TFAI being free of malaria, bilharziosis and smallpox, the French Medical Service has to maintain a firm grip on possible spreading. Kalo area might be a favorable reservoir due to the prevailing ecological conditions. Tuberculosis is so widely common that any control in the TFAI would imply a BCG campaign on both sides of the border within an inter-governmental plan of operations.
 ...
PMID:[Immunization campaign in Ethiopia (author's transl)]. 53 43

Various workers, including T. D. Stewart, claim that the aboriginal Americas were relatively disease-free because of the bering Strait cold-screen, eliminating many pathogens, and the paucity of zoonotic infections because of few domestic animals. Evidence of varying validity suggests that precontact Americns had their own strains of treponemic infections, bacillary and amoebic dysenteries, influenza and viral penumonia and other respiratory diseases, salmonellosis and perhaps other food poisoning, various arthritides, some endoparasites such as the ascarids, and several geographically circumscribed diseases such as the rickettsial verruca (Carrion's disease) and New World leishmaniasis and trypanosomiasis. Questionably aboriginal are tuberculosis and typhus. Accordingly, virtually all the "crowd-type" ecopathogenic diseases such as smallpox, yellow fever, typhoid, malaria, measles, pertussis, polio, etc., appear to have been absent from the New World, and were only brought in by White conquerors and their Black slaves. My hypothesis is that native American medical care systems--especially in the more culturally advanced areas--were sufficiently sophisticated to deal with native disease entities with reasonable competence. But native medical systems could not cope with the "crowd-type" disease imports that struck Indian and Eskimos as "virgin-field" populations. Reanalysis of native population losses through a genocidal combination of diease, war, slavery and attendant cultural disruption by Dobyns, Cook and others strongly suggest that traditiona estimates underplayed the death toll by a factor of the general order of ten. This would make for an immediately pre-contact Indian population of some 90-111 million instead of the tradition 8-11 million. Evidence is growing that Indians may have been no more susceptible to new pathogens that are other "virgin soil" populations, and thus their immune systems need not be considered less effective than those in other people. Present-day high mortality rates in Indians of both continents from infectious disease imports may be more socioeconomic than anything else.
 ...
PMID:Aboriginal new world epidemiolgy and medical care, and the impact of Old World disease imports. 79 20

Malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. The most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. Reasons for this trend are discussed. Efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in S.E. Asia have added new dimensions to the problem. Malaria is still widely prevalent in the tropics and falciparum malaria, holoendemic in much of Africa, remains a major cause of death with its most serious impact on pregnant women and children. The emergence and spread of drug resistant strains of this parasite in parts of the world is a cause for serious concern. Quartan malaria is also an insidious corruptor of health in childhood and commonly causes the nephrotic syndrome. Neonatal jaundice, often associated with G6PD deficiency, is increasing in frequency in urban areas of Africa and now constitutes a significant hazard to the newborn and requires urgent investigation. These problems in tropical paediatrics indicate the need for urgent reappraisal of our role as a profession in the affairs of the tropical developing world.
 ...
PMID:Aspects of tropical paediatrics. 79 3

Great streams of tourists flow every year from the Federal Republic to southern countries. The danger of infection with serious tropical diseases such as smallpox, cholera or leprosy is fairly small, statistically speaking. Even exotic parasitoses merit only individual medical interest in the majority of cases. Of greater importance are the cosmopolitan infectious diseases such as typhoid fever, paratyphoid, salmonella enteritis, poliomyelitis, viral hepatitides which are transmitted orally and altogether are imported in no small numbers. The alteration of the mode of living caused by the holiday and frequently a false confidence in the hygienic conditions favor the infection. Almost independent of the behavior of the tourists are the infections produced by insect bites, such as malaria or the leishmaniases, which often end fatally for lack of recognition. Here, a better enlightment of the travelers, the use of prophylactic agents and improvement of diagnosis must be instituted.
 ...
PMID:[Tourism and risk of infection (author's transl)]. 82 9

A project for total leprosy case detection particularly early leprosy cases was undertaken in Wardha District which has a rural population of about 6 lacs in 905 villages, through an integrated survey with the help of all health workers like Leprosy Technicians, Sanitary Inspectors, Co-ordinators, Malaria Workers, Smallpox Vaccinators and Auxillary Nurse Midwives. The training given to the Non Leprosy Health Worker was for a period of 3 days making them just fit to suspect all leprosy cases. The final diagnosis was to be made by the fully trained Leprosy Technicians. The surveys were conducted in batches of 3 to 4 workers. Surveys were conducted for 4 weeks at a stretch and working for 5 days every week. Every year two such integrated surveys were conducted. From November 1973 to December 1975, four such surveys were undertaken. During the other period, Leprosy Technicians were conducting the normal surveys. It was found that through these integrated survey it is possible to undertake the survey of all the villages once in two years and the case detection rate at the end of the 4th survey was found to be 85.5% of the estimated cases in the rural areas. Normally, it would have taken about 5 years to complete the survey of all the villages by the Leprosy Technicians alone, and the case detection rate could not have been more than 70 to 75%. Through this programme, Leprosy patients in every early stages have been detected. The paper discusses the methods, planning and the results obtained.
 ...
PMID:Integrated surveys as a tool for early case detection in leprosy control programme. 102 30

The American population developed, during thousands of years, free of epidemics that had been attacking Europe, Asia and Africa. The European and African migrations, after Columbus's first trip, produced an epidemic invasion of influenza, smallpox, measles, yellow fever, malaria, diphtheria, typhus, and other diseases that attacked the immunologically virgin populations and produced a very high mortality, with a diminution of the indigenous population of more than 90% in many places. According to historical evidence, the first epidemic was influenza, produced by swine strain of virus, immediately followed by smallpox. The Spaniards mated freely with the Indians producing a mixed race called the Mestizo, who were immunologically more capable of defending themselves against various viruses, bacteria, and parasites brought over from the Old World. Marriage between the races also was sanctioned by Queen Isabella (1503) and Fernando I (1515). With these new genetic immunologic defenses against infections, the Mestizo eventually made up the majority of the population of Indians in the New World.
 ...
PMID:Epidemic hecatomb in the New World. 148 72

World Health Organization's goal Health for All is the starting point for a most ambitious health policy ever. The paper analyzes the role of epidemiology in the Organization's work, particularly in the Health for All development. During WHO's early years, epidemiology helped to design and carry out major public health campaigns against such scourges of the humanity as yaws, tuberculosis, malaria and small pox. When the Organization during the 1960s began to emphasize the need to develop the infrastructure of health care, health services research partly replaced epidemiology as WHO's main scientific allay. After the Health for All policy was launched in 1987, epidemiology has again played a major role in establishing the scientific background of the policy. The European experiences show how the epidemiologists can help WHO to identify the most important health problems and set achievable and measurable targets for them. The paper concludes that epidemiology serves to identify problems, show ways to solve them, monitor the changes in the situation and evaluate the achievements.
 ...
PMID:Epidemiology and Health for All. The role of epidemiology in a health policy. 160 35

In this article it is outlined the work of doctor Bustamante in fighting against diseases such as yellow fever, typhus, malaria, and smallpox; and the development and impel that this professional gave to preventive and social medicine is pointed out. It is established that health care professionals currently must not only highly studied and prepared, as they should manage all features related with public health, but also change-men-and-women who are capable to influence future generations, which will be the responsible in relocating men at the equilibrium point concerned to their health. Said equilibrium point is not only modified in its biopsychosocial aspect, but also its essence is deeply affected. This paper is a warning to physicians to fight together in response to humanity, that has set their confidence in them, as the current problem of drugs and dependence to drugs unhinges everything wholeness. To doctor Suarez is intolerable that, in spite of technological advances in the world, yet exist deaths caused by pneumonia or diarrhea. The hazards of the century are frightened: nuclear war and AIDS; but the characteristics that have distinguished human species and allowed its survival and superation are trusted: mental activity, ability of judgement, and consciousness; which are valuable for a deep philosophic discussion that allows us to continue our advance. An enumeration of the medicine achievements in this century is made.
 ...
PMID:[Health challenges as the second millenium is ending. Conceptual epidemiology, social pathology, medicine and professional ethics]. 208 47

In Germany, the last period of the Second World War and the following years were characterized by deficiencies of hygiene which had not occurred previously in Middle Europe during the 20th century. There were focuses of typhus, typhoid fever, tuberculosis, diphtheria, scarlet fever, and meningitis. Insufficiencies in the removal of faeces caused high incidences of shigellosis, hepatitis A, and ascariasis. As a result of insufficient body care, many people were infested with fleas, lice and scabies. The migration of large proportions of the population resulted in an increasing prevalence of syphilis an gonorrhea. As the population resettled, the first steps towards reorganization of public health could be done. The spread of typhoid fever was controlled by drinking-water disinfection with chlorine, repair of sewage systems, and patient isolation. The application of DDT helped to reduce scabies and pediculosis, resulting in decreasing typhus risks. During the first two decades after the war, there was a steady decrease of the incidence of infectious diseases. The reconstruction of the towns resulted in improved housing conditions and a decreasing number of persons per housing area, reducing the intensity of physical contacts of the inhabitants with each other. The nutrition and clothing situation of the population improved, which, in addition to a general rise of the standards of hygiene, brought about an increase of the individual resistance to infection. A further reduction of sporadic and epidemic outbreaks of infectious diseases was achieved by the introduction of chemotherapy and antibiotics. Increasing prosperity was accompanied by new problems of hygiene. Infectious diseases almost eradicated in West Germany, were imported by air travellers. Ten imported cases of smallpox were reported between 1957 and 1972, eight of which originated from Southeast Asia. Malaria, imported by German and foreign soldiers, had not been uncommon after the end of the war but had been easy to control by insecticides and antimalarials. As tourism expanded, a new wave of imported malaria cases was reported. In West Germany there is, however, no more spread of the disease under present conditions, cholera caused similar problems. The 1961 cholera epidemic started in Southeast Asia and caused minor outbreaks in Mediterranean countries like Italy and Spain. A significant spread of the disease throughout Europe was prevented by generally high standards of drinking water and sewage treatment. Sporadic cases of typhoid fever were imported from countries with low standards of hygiene.(ABSTRACT TRUNCATED AT 400 WORDS)
 ...
PMID:[The success of hygiene in the last 40 years]. 250 Jul 98

During the past eight decades, a large number of studies have examined the possible relationship between blood type and infection. Many publications reflect uncritical attempts to mathematically link unstratified or random data. The interaction of pathogen and erythrocyte membrane may reflect antigenic similarity, adhesion through specific receptors, or modulation of antibody response. Anthropological surveys suggest that the geographic and racial distribution of human blood groups reflects susceptibility of populations with specific blood types to the plague, cholera, smallpox, malaria and other infectious diseases.
 ...
PMID:Relationship between infectious diseases and human blood type. 250 33


1 2 3 4 5 6 7 8 9 10 Next >>