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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chickens infected with the malarial parasite Plasmodium gallinceum produced green droppings: the predominant pigment was biliverdin. Droppings of identical appearance were produced by chicks injected with phenylhydrazine, a haemolytic agent: it is concluded that the catabolism of haemoglobin resulting at least in part from malarial haemolysis produces excess bile pigments which appear in the droppings. Other chicken diseases in which green droppings are "a characteristic objective symptom are fowl typhoid, Newcastle disease (Doyle's form), spirochaetosis and fowl cholera. The correlation of this symptom with haemolytic or other secondary anaemia is discussed and its value in field outbreaks of avian malaria as an indicator of the need for immediate therapy is emphasised.
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PMID:Biliverdin production in chickens infected with the malarial parasite Plasmodium gallinaceum. 1876 33

Several interferon inducers (Newcastle disease virus, statolon, and poly rI:poly rC) as well as exogenous mouse interferon protect mice from sporozoite-induced Plasmodium berghei malaria, as long as they are administered before the end of the preerythrocytic phase of development of the parasite. The protective effect of the interferon inducers was related to their interferon-inducing effect; the protective effect of the interferon preparations was related to the interferon titer of the preparations, and it exhibited other attributes of interferon such as species specificity. In contrast to sporozoite-induced infection, blood forms-induced P. berghei malaria was only weakly susceptible to the protective effect of interferon inducers. This difference may provide an approach to study the mechanism of protection. The growth in cell cultures of another intracellular protozoon, Toxoplasma gondii, is also inhibited by interferon (22). The fact that P. berghei and T. gondii (as well as another group of intracellular parasites susceptible to interferon, the Chlamydia) have their own ribosomes raises questions, concerning the role of host cell ribosomes in the host cell-parasite relationship of these intracellular parasites and in the mechanism of interferon action against them, that can be approached experimentally. The possibility of therapeutic or prophylactic application of interferon or of its inducers to certain protozoal diseases of man and of other animals is still remote, but it has to be considered for long range planning.
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PMID:Interferon and interferon inducers in protozoal infections. 1987 69

Birds can host a wide spectrum of pathogens. While in the air, sea or on the ground they can carry ticks on their skin and microbes in the intestines (campylobacter, salmonella) or blood (viruses, borrelia spirochetes and protozoa). The high body temperature favors the growth of Borrelia garinii (causing neuroborreliosis), Campylobacterjejuni and certain viruses. Viral infections carried by birds include West Nile-virus and Japanese encephalitis, Newcastle disease and flu. Less studied are infections of the birds themselves, like bird malaria. Infections can be prevented by avoiding contacts to feces, vector animals (ticks and mosquitoes) and by hygienic food processing.
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PMID:[Birds as carriers of human disease]. 2509 76