Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nearly 40 million journeys abroad were recorded from the Federal Republic of Germany last year. 60-70% of travellers going to southern countries seek medical advice for preventive measures, particularly in Public Health centres. Inquiries for vaccinations are prevalent. Current aspects of immunization against yellow fever, cholera, tetanus, polio, typhoid fever, hepatitis A, hepatitis B, rabies meningococcal meningitis, European tick-borne encephalitis, measles and tuberculosis are discussed. Finally, some remarks on malaria prevention, hygiene, health insurance and information services are given in brief.
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PMID:[Preventive health care in travel, especially vaccinations]. 253 28

The case notes of all patients who died over the January 1980 to December 1985 period in Tikur Anbessa Teaching Hospital, Addis Ababa, Ethiopia, as a result of conditions associated with pregnancy, labor, and puerperium were reviewed in an effort to identify the most common causes of maternal death. Postpartum autopsy seldom was possible; consequently, the cause of death was based on clinical findings only. 216 deaths occurred over the 6-year period; there were 22,404 live births in the same period, giving a maternal mortality rate (MMR) of 9.6/1000. This rate included deaths from complications following abortions. 197 of the deaths occurred in women who were not booked into Tikur Anbessa Hospital. In terms of direct causes of death, abortion, puerperal sepsis, and ruptured uterus together accounted for 75.9% of deaths. Of indirect causes, infectious hepatitis, relapsing fever, and malaria accounted for 56.8% of deaths. Of deaths due to abortion, 21/48 occurred in nulliparas, and 25 were below age 19. Of the deaths caused by ruptured uterus, 20/29 occurred in multipara, and all of those women were from rural areas. The majority of deaths from hepatitis occurred in the 30-34 years age group. In Ethiopia, the maternal mortality rate is high because of both poor or inadequate antenatal and postnatal care as well as because of poor transportation and communication systems.
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PMID:A six-year review of maternal mortality in a teaching hospital in Addis Ababa. 341 42

General screening investigations with various antigens were carried out with a view to further specific investigations being carried out on the Cape Verde Islands concerning infectious diseases. Serological positive reactions were found in Mumps, Adeno, PLT, Cytomegaly, Herpes, Para-influenza 1, 2, 3, Influenza A and B, Mycoplasmosis, RS-Virus, Gonorrhoea, Hepatitis A and B, R. conori, Malaria, Syphilis, Brucella abortus, Brucella melitensis, Varicella, Legionella, Picornavirus, Measles, German Measles, Listeriosis, Toxoplasmosis and Amoebic dysentery.
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PMID:Serological screenings of various infectious diseases on the Cape Verde Islands (West Africa). 344 44

Nine patients with acute liver failure due to Plasmodium falciparum liver injury admitted to the Rajgarhia Liver Unit of the All-India Institute of Medical Sciences during 1982-84 are presented. The liver was palpable in all the patients, and eight had splenomegaly. Investigations revealed mild to moderate abnormality in liver function tests. All were negative for the markers of acute infection due to hepatitis A and B viruses. Blood film examination showed P. falciparum alone in seven and along with P. vivax in the remaining two patients. Liver histology, which was identical in all eight patients where liver biopsy was done, showed centrizonal necrosis and hyperplastic Kupffer cells loaded with malarial pigment. All the patients recovered with specific anti-malarial and supportive treatment. Our observations suggest that malaria due to P. falciparum may present as jaundice and encephalopathy which stimulates acute hepatic failure due to fulminant hepatitis.
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PMID:Acute hepatic failure due to Plasmodium falciparum liver injury. 355 21

Following two cases of Marburg virus disease in Kenya in 1980, viral haemorrhagic fever surveillance was undertaken in western Kenya. Over a 21-month period investigations, including virus isolation attempts, patient and contact serology, visits to areas where suspected cases occurred, interviewing family members and neighbours of suspected cases and following up any additional illnesses in these areas, were carried out. During the study two cases were found that were likely to have been Ebola haemorrhagic fever based on rising antibody titres or positive serology in contacts. Diagnoses of hepatitis A, hepatitis B, malaria, bacterial septicaemia or other causes were arrived at in 24 cases. No diagnosis could be made in 26 instances. 741 human sera were tested for antibodies against Marburg, Ebola, Congo haemorrhagic fever, Rift Valley fever or Lassa fever viruses by indirect fluorescence. Eight sera were positive for Ebola virus antibodies, all of which were from suspected cases or contacts of suspected cases. Two sera were antibody positive to Congo virus and one had antibodies against Rift Valley fever virus. No Marburg or Lassa virus antibodies were detected.
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PMID:Viral haemorrhagic fever surveillance in Kenya, 1980-1981. 668 36

A survey is given of the occurrence of communicable diseases in the Federal Republic of Germany including Berlin (West) in 1979. The epidemiological situation was dominated by salmonellosis, infectious hepatitis, scarlet fever, and meningitis. There was a striking increase in imported tropical diseases, such as malaria and leprosy. Poliomyelitis continued to decrease. There was an insignificant number of influenza cases in the winter 79/80. Due to the coming into force of the Amendment of the Federal Communicable Diseases Act on 1 January 1980 the obligation to notify communicable diseases has been changed in some respects. Moreover, the statistical data on communicable diseases have been collected and published only quarterly.
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PMID:[The epidemiologic situation of infectious disease in West Germany in 1979]. 721 10

In 1979, British laboratories participating in the American of Clinical Pathologists' survey reported five cases of tuberculosis, four of chickenpox, four of salmonellosis or shigellosis, one malaria, and one hepatitis A infection. Microbiology workers were most affected, but at least six infections were not attributable to work. All cases recovered.
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PMID:Hepatitis and other infections in clinical laboratory staff, 1979. 725 7

The incidence of nine water-related diseases in the Brak oases of the Sahara desert, before and after the installation of water treatment plants, are reported. Immediately following installation of the plants there was a drop in the incidence of most of the water related diseases. There then followed a gradual deterioration in the treatment plants and within a year the incidence of four of the diseases was again rising. Furthermore neither malaria or giardiases showed any drop in incidence over the study period. Bacillary dysentary, infectious hepatitis and bilharzia did however drop significantly over the three years. A correlation between bacillary dysentary and the mean noon-time temperature for two of the three years was noted.
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PMID:The incidence of water-related diseases in the Brak area, Libya from 1977 to 1979, before and after the installation of water treatment plants. 732 13

Under analysis was the course of the postoperative period in 216 patients subjected to closed mitral commissurotomy. The risk of local infectious complications was found to be higher in patients with the IVth stage of mitral stenosis having lymphopenia, hypopotassemia, hyponatremia, hypochromic anemia, higher ESR in the postoperative period who had malaria and infectious hepatitis in the medical history.
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PMID:[Certain factors increasing the risk of local infectious complications following closed mitral commissurotomy]. 742 54

Liposomes have been proposed as vehicles for vaccines against parasitic and viral illnesses. Experimental vaccines against malaria, HIV, hepatitis A, and influenza virus have been shown to be safe and highly immunogenic in several human trials. Analysis of the intracellular trafficking patterns of liposomal antigen reveals that after being phagocytosed by macrophages, liposomal antigen readily escapes from endosomes into the cytoplasm of the macrophages. It is proposed that liposomal peptide antigen can enter either the Golgi apparatus or the endoplasmic reticulum and thereby interact with MHC class II or class I molecules. The intracellular cytoplasmic trafficking patterns of liposomal antigens raise the possibility that liposomes may have utility in human vaccines for induction of either humoral immunity or cytotoxic T lymphocytes.
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PMID:Liposomal vaccines: clinical status and immunological presentation for humoral and cellular immunity. 762 48


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