Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024530 (malaria)
 44,886 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cell surface components of viridans streptococci and enterococci have been shown to stimulate the release of tumor necrosis factor alpha (TNF) and interleukin-6 from monocytes/macrophages. In the sera from 10 patients with subacute enterococcal or streptococcal endocarditis, however, the levels of both cytokines were low or undetectable, with elevated TNF levels on admission in 3 patients with complicated disease. Soluble TNF receptor levels were significantly elevated compared with those of healthy controls. When patients with malaria were used as a control group of acute intravascular infection with high circulating TNF values, the ratio between soluble TNF receptors and TNF on admission was significantly greater in the patients with subacute bacterial endocarditis. Besides different amounts of circulating TNF, enhanced TNF receptor shedding may have an important role in the pathogenesis of subacute versus acute clinical disease following human intravascular infection.
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PMID:Circulating tumor necrosis factor alpha (TNF), soluble TNF receptors, and interleukin-6 in human subacute bacterial endocarditis. 822 16

The causes of fever in 171 cases 10 days after 1527 cases of open heart surgery were analysed. The common noninfectious causes of fever were postpericardiotomy syndrome (35.8%) and drug fever (26.9%). The infectious causes of fever were respiratory system infection (18.1%), chest wall and incision infection (9.9%), infectious endocarditis (7.0%) and transfusion malaria (2.4%). In this paper, the diagnosis, prevention and treatment of common causes of fever after open heart surgery were discussed. The authors believed that etiologic diagnosis of fever and reasonable antibiotic use were key measures.
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PMID:[Diagnosis and treatment of causes of fever after open heart surgery]. 827 39