Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024523 (malabsorption)
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Human Gene/Protein
ADP-ribosylation factor-like 1 11.1
microsomal triglyceride transfer protein large subunit 11.1
ADP-ribosylation factor related protein 1 10.5
MGA1 10.4
CUBN 9.5
intrinsic factor-cobalamin receptor 9.5
sodium/bile acid cotransporter 9.5
ECRP 9.5
CEL protein 9.5
SAR1B 9.2
NHLRC2 9.1
TREH 9.1
proton-coupled folate transporter 8.9
THSD1 8.9
intrinsic factor 8.9
EIF6 8.8
Formiminotransferase-cyclodeaminase 8.8
alpha heavy chain 8.7
lactase 8.6
pregastric lipase 8.6
cblD 8.4
HSD3B7 8.4
cubilin 8.4
cblF 8.3
organic solute transporter alpha 8.3
HCP1 8.3
ARFRP1 8.3
CD320 8.2
Cubilin 8.2
DNAJC21 8.2
thiamine transporter 1 8.2
dNT-2 8.1
OSTbeta 8.0
PFIC 8.0
seven in absentia homolog 1 7.9
ileal bile acid transporter 7.9
MYO5B 7.8
MTTP 7.8
NOS1 protein 7.8
FTCD 7.8
SLC5A1 7.6
transcobalamin II 7.5
reduced folate carrier 7.5
THTR2 7.4
ASBT 7.4
haptocorrin 7.4
B12 7.4
B-12 7.4
tissue transglutaminase 7.4
FOLR2 7.4
B(0)AT1 7.4
SBDS 7.3
GLP-2R 7.3
CNNM4 7.3
Maid 7.3
SLC23A1 7.3
gastric lipase 7.2
OSTalpha 7.2
Diamine oxidase 7.2
RNF5 7.2
Gamma-glutamyl carboxylase 7.1
GLP2 7.1
CDC50A 7.1
PLRP1 7.1
EML1 7.1
RFX6 7.0
claudin-8 7.0
SLC5A7 7.0
IGS 7.0
SGLT1 7.0
DQ2 7.0
TERE1 7.0
Apolipoprotein A-II 7.0
CDG Ia 7.0
ZIP4 7.0
congenital chloride diarrhea 7.0
Cyclin B2 7.0
p10 protein 7.0
pancreatic lipase-related protein 2 6.9
LIPA 6.9
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Disease
Colonic dysfunction 12.1
malnutrition; mild 12.1
Gastrointestinal inflammatory conditions 12.1
malabsorption 12.1
Juvenile dermatitis herpetiformis 12.1
Hypogammaglobulinemic sprue 12.1
Campylobacter gastritis 12.1
Dihydrofolate reductase deficiency 12.1
glucoglycinuria 12.1
Drug-induced diabetes mellitus 12.1
Osmotic diarrhea 11.6
Other obesity 11.5
Crohn's jejunitis 11.5
Brown bowel syndrome 11.4
Collagenous sprue 11.2
Imerslund 11.1
Bronchiectasis, recurrent 11.1
Diarrhea predominant irritable bowel syndrome 11.1
Intestinal ulceration 11.1
Mixed proteinuria 11.1
Diverticulosis of the jejunum 11.1
Late neonatal hypocalcemia 11.1
familial hypolipoproteinemia 11.1
tropical sprue 10.9
Enteric hyperoxaluria 10.6
hereditary neoplastic syndrome 10.5
Childhood celiac disease 10.5
Diabetic diarrhea 10.5
Looser-Milkman 10.5
hypercalcaemia due to parathyroid adenoma 10.5
R-binder deficiency 10.5
Lymphosarcoma cell leukemia 10.5
Chronic peptic ulcer 10.5
chylomicron retention disease 10.5
steatorrhea 10.3
Phrynoderma 10.3
Secondary lactose intolerance 10.3
Hepatic osteodystrophy 10.3
Gastrointestinal amyloidosis 10.3
Immunoproliferative small intestinal disease 10.2
disaccharidase deficiency 10.2
sprue 10.1
Typhoid and paratyphoid fevers 10.1
Autoimmune enteropathy 10.1
Eosinophilic gastroenteropathy 10.1
VKCFD1 10.1
Hereditary folate malabsorption 10.1
Mesenteric fibrosis 10.1
Adult celiac disease 10.1
Tropical ataxic neuropathy 10.1
lactose intolerance 9.9
CSID 9.9
functional diarrhea 9.8
glutamate formiminotransferase deficiency 9.8
Pancreatic steatorrhea 9.8
Acute dermatitis 9.8
blind loop syndrome 9.8
Diencephalic syndrome 9.8
Biermer 9.7
small bowel lymphoma 9.7
Secondary oxalosis 9.6
Mechanical intestinal obstruction 9.5
Congenital lactase deficiency 9.5
Renal vascular disease 9.5
Protracted diarrhea 9.5
hypoglobulinemia 9.4
glucose-galactose malabsorption 9.4
transcobalamin II deficiency 9.4
pancreatic insufficiency 9.3
CDG Ix 9.3
Pseudo-Bartter syndrome 9.3
Intestinal lymphoma 9.3
Lymphocytic-plasmacytic enteritis 9.3
viral arthritis 9.2
short bowel syndrome 9.1
Oxalate nephropathy 9.1
VKCFD2 9.1
Corneal erosion 9.1
Mesenteric infarction 9.1
CMV gastroenteritis 9.1
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Symptom
Neck discomfort 11.1
Gastrointestinal signs and symptoms 9.3
Gastrointestinal discomfort 8.5
Food intolerance 8.5
jaundice of the skin 8.1
Watery diarrhea 8.0
change in stool 7.8
bloating 7.6
ischuria 7.4
Lung hyperinflation 7.3
abnormal taste 7.2
Gastrointestinal symptoms 7.1
Wind 6.9
localized abdominal pain 6.9
diarrhea 6.9
hypoproteinemia 6.7
carpopedal spasm 6.6
koilonychia 6.4
belching 6.4
Beau's lines 6.4
infant diarrhea 6.3
decreased appetite 6.3
Severe diarrhea 6.3
clubbing 6.3
Chronic abdominal pain 6.3
hyperemesis 6.2
abdominal discomfort 6.0
abdominal cramps 6.0
Bitot's spots 6.0
intestinal angina 6.0
inanition 5.9
Neurologic symptoms 5.6
cachexia 5.5
intestinal bleeding 5.4
abdominal pain 5.4
autodigestion 5.4
emaciation 5.4
pedal edema 5.3
Joint hypermobility 5.1
anorexia 5.0
leg cramps 4.9
constipation 4.8
menometrorrhagia 4.8
tenesmus 4.8
bone pain 4.7
stomach pain 4.7
leg edema 4.7
Catch 4.7
ketonuria 4.6
giddiness 4.4
giddiness 4.4
vomiting 4.4
colic 4.4
lethargy 4.3
acute abdomen 4.2
asthenia 4.2
hepatomegaly 4.2
ataxia 4.1
syncopal episodes 4.1
hyperesthesia 4.0
hyperemesis gravidarum 4.0
hepatosplenomegaly 4.0
pallor 4.0
dark urine 3.9
lassitude 3.9
nausea 3.9
muscle cramps 3.9
chronic constipation 3.8
Psychiatric symptoms 3.8
cerebellar ataxia 3.7
heartburn 3.6
Poor sleep 3.6
prostration 3.5
loss of taste 3.5
photophobia 3.5
hunger 3.4
abdominal fullness 3.4
ophthalmoplegia 3.4
arthralgia 3.3
neurological disability 3.2
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Drug
Nascobal 11.1
Nascobal 11.1
Inversine 9.8
Pancrease 9.7
Inversine 9.1
Teduglutide 9.0
Giardiasis 8.7
Tixocortol pivalate 8.5
Cytomel 8.4
Cytomel 8.3
Duphalac 8.2
Cobalamin 8.1
Lactase 8.1
Questran 7.9
Vitamin B12 7.6
Rocaltrol 7.6
Alfacalcidol 7.6
Calcium citrate 7.5
Potassium citrate 7.4
Colesevelam 7.4
Orlistat 7.3
Protein hydrolysate 7.2
Lactose 7.1
Colestipol 7.1
Methotrexat 7.0
lactose 6.9
Venofer 6.5
Miglustat 6.5
Synthroid 6.4
Fructose 6.3
Epidoxorubicin 6.3
Enprostil 6.2
Folic Acid 6.1
Vitamin K 6.1
Vitamin B 6.0
Dextran sulfate sodium 6.0
Tiopronin 6.0
Virginiamycin 5.9
Sterile water 5.9
Catapres 5.8
Pemetrexed 5.7
Tolfenamic acid 5.7
Domin 5.6
Synthroid 5.6
Valganciclovir 5.6
Phenprocoumon 5.6
Vitamin E 5.5
Neoral 5.4
vitamin E 5.1
Trimethoprim-sulfamethoxazole 5.1
Tinidazole 5.0
Pyridoxal phosphate 4.9
Aprepitant 4.8
Nitazoxanide 4.8
Beta-2 4.7
Omeprazole 4.7
Galactose 4.6
Vitamin A 4.5
Cimetidine 4.4
Cimetidine 4.4
Diamminedichloroplatinum 4.4
Olmesartan 4.4
Gastro 4.3
niacin 4.1
RAL 4.1
Zmax 4.0
GNA 4.0
PTH 4.0
Misoprostol 4.0
Denosumab 4.0
Sandostatin 3.8
Sandostatin 3.8
Myricetin 3.8
Vena 3.8
Vena 3.8
Rimonabant 3.7
Bifidobacterium 3.7
Meconium 3.7
Tacrolimus 3.7
Posaconazole 3.6
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Enzyme
lactase 8.6
lactase-phlorizin hydrolase 7.1
ketohexokinase 7.0
triokinase 7.0
sucrase-isomaltase 6.8
lactase-phlorizin hydrolase 6.7
sucrase 6.6
conjugase 6.3
transglutaminase 6.2
trehalase 5.9
glyoxylate reductase 5.8
glyoxylate reductase 5.8
CYP8B1 5.6
alpha-glucosidase 5.5
3-oxoacid CoA-transferase 5.5
monoacylglycerol acyltransferase 5.4
methylenetetrahydrofolate dehydrogenase 5.3
DAP II 5.3
invertase 5.2
carnosinase 5.1
pantothenate kinase 5.1
enterokinase 5.0
formyltetrahydrofolate synthetase 4.9
methylenetetrahydrofolate dehydrogenase 4.9
lipase 4.8
hydroxypyruvate reductase 4.6
3alpha-hydroxysteroid dehydrogenase 4.6
hydroxypyruvate reductase 4.5
methionine synthase reductase 4.4
dihydropteridine reductase 4.4
methionine synthase 4.4
acetylesterase 4.4
cyclohydrolase 4.3
methionine synthase 4.3
PPH 4.2
CYP7A1 4.1
bile salt hydrolase 4.1
CPL 4.1
methylenetetrahydrofolate reductase 3.8
methylenetetrahydrofolate reductase 3.8
uridine phosphorylase 3.8
diamine oxidase 3.8
hyaluronate lyase 3.8
ceruloplasmin 3.8
transketolase 3.7
GCA 3.6
tryptophan hydroxylase 3.6
fructokinase 3.6
isoamylase 3.6
squalene epoxidase 3.5
AGT 3.5
biotinidase 3.5
HCS 3.4
aminopeptidase A 3.4
glucoamylase 3.4
MDP 3.3
elastase 3.3
chymotrypsin 3.2
bromelain 3.1
TRS 3.1
CYP27A1 3.0
leucine aminopeptidase 3.0
meprin 3.0
alkaline phosphatase 2.9
lecithin:cholesterol acyltransferase 2.9
galactokinase 2.8
CPM 2.7
LPL 2.7
gamma-glutamyl transpeptidase 2.6
phenylalanine hydroxylase 2.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.6
glycerol kinase 2.6
Mg2+-ATPase 2.6
prolyl endopeptidase 2.5
trypsin 2.4
acyl-CoA synthetase 2.4
dipeptidyl peptidase IV 2.4
beta-galactosidase 2.3
tryptophan 2,3-dioxygenase 2.3
arginine deiminase 2.3
more...
Compound
C24H40O5 10.1
SKF 12185 9.1
Previtamin D3 9.1
Sodium glycocholate 8.2
Cobalamin 8.1
D-Xylose, 8.0
36L 8.0
Cobinamide 7.8
Triolein 7.8
Fusarenon-X 7.4
Biguanide 7.3
Lactulose 7.3
Colestipol 7.1
Lactose 7.0
Carboquone 7.0
6-Keto-PGF1a 7.0
2-methylcitric acid 7.0
Xylose 6.9
Acarbose 6.9
Carboquone 6.7
Carboquone 6.7
Carboquone 6.7
Carboquone 6.7
Chenodeoxycholic acid 6.6
Sulfisoxazole 6.4
Sulfoxide 6.4
Glycocholic acid 6.3
DPBS 6.3
Vitamin K 6.3
Fructose 6.2
xylose 6.2
Miglitol 6.2
Ursodeoxycholic acid 6.2
isopropyl palmitate 6.2
Retinyl acetate 6.1
Cyanocobalamin 6.1
Pterin 6.0
Phentermine 6.0
Parenteral 6.0
Captan 6.0
25-hydroxycholecalciferol 5.8
vitamin D 5.7
CFN 5.7
Cilag 5.6
Deoxycholic acid 5.6
cholestan-3-one 5.6
dihydroxyacetone-phosphate 5.4
Loperamide 5.4
Mithramycin 5.4
Maltodextrin 5.3
25-Hydroxyvitamin D 5.3
Virginiamycin 5.3
Sorbitol 5.3
5-formyltetrahydrofolate 5.3
Sulfasalazine 5.3
Vitamin E 5.2
Vitamin D 5.2
2-heptanol 5.0
N-methylnicotinamide 5.0
Spiramycin 5.0
PGA 5.0
oxalate 4.9
Spiramycin 4.9
Vitamin D3 4.9
nicotinic acid 4.9
Erythritol 4.9
1,6-hexanediamine 4.8
Neomycin 4.8
Phlorizin 4.8
Vitamin D3 4.8
Cholic acid 4.7
Ethosuximide 4.7
Bethanechol 4.6
Galactose 4.6
Fructosamine 4.6
5,10-methenyltetrahydrofolate 4.6
fructose-1-phosphate 4.6
octanoyl-CoA 4.6
Thyroxine 4.5
Vitamin A 4.5
more...