Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024523 (malabsorption)
 7,319 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Content of IgA, IgG, IgM, C3 and C4 components of complement, properdin factor B, acid glycoprotein, alpha 1-antitrypsin, transferrin and ceruloplasmin were studied using immunochemical procedures in blood serum, gastric and duodenal contents of healthy persons and of patients after stomach resection. In patients with symptoms of malabsorption concentration of IgA and IgG was drastically increased in gastric and duodenal contents by 51% and 188%, respectively, and by 53% and 371%, respectively. Local activation of the complement system was also observed, which involved an increase of C3 component in stomach and small intestine by 122% and 31%, respectively. As a result of postoperative anastomositis content of albumin and the properdin factor B was distinctly increased in the duodenum. The data obtained suggest that studies of various functional proteins in gastric and duodenal contents are recommended for evaluation of a disease genesis as well as for diagnosis of acute local inflammation.
 ...
PMID:[The local humoral immune system in patients with malabsorption syndrome]. 816 Apr 29