Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024523 (malabsorption)
 7,319 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It is possible to reduce side effects of oral contraceptives by individualizing the dosage and type of pill on the basis of such factors as length and regularity of normal cycle and sensitivity to endogenous progesterone, as demonstrated by premenstrual tension and depression. Tailor-made pills would provide dosages of either estrogen, progesterone, or a combination, calculated on the amount that is necessary to control the ovulatory cycle and subsequently adjusted for any observed side effects. The choice of estrogen or progesterone shoul d be based on a careful medical history that takes all relevant factors into consideration. Most marketed oral contraceptives are combinations designed to contain the minimum effective dosage; however, they must also compensate for such influences as short cycles, malabsorption, and inconsistency in taking the pills. These factors can be dealt with better on an individual basis by the practitioner's prescription of doses based on medical history. This practice may be considered threatening by pharmaceutical companies, but physicians must avoid marketing pressures and concentrate on optimal treatment of individual patients.
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PMID:Letter: Side effects of oral contraceptives. 114 34