Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024312 (lymphopenia)
 4,859 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The examination of 118 intestinal disorders caused by Ps. aeruginosa in patients aged 18-60 provided evidence on its higher incidence in summer and autumn, acute onset, short latent period, systemic toxic and dyspeptic syndromes. Intestinal picture involved syndromes of gastroenteritis, gastroenterocolitis, in the severe course--of hemocolitis. Grave forms of Ps. aeruginosa infection entail drastic changes in immune status registered till the discharge from hospital: T-lymphopenia, high CIC levels, a lower immunoregulatory index.
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PMID:[Clinico-immunologic characteristics of acute intestinal diseases caused by Pseudomonas aeruginosa]. 208 80

Salmonella typhimurium infection was diagnosed in 186 patients aged 18-56. The clinical picture was that of gastroenteritis (73.1%), enteritis (14.0%), gastritis (6.45%), gastroenterocolitis (6.45%). Salmonellosis of moderate severity presented in 88.7% of patients, a severe course occurred in 11.3%. Concomitant disorders arose in 22.6% of cases. Immunological investigation disclosed T-lymphopenia, reduced number of multireceptor RFC, both T-helpers and T-suppressors. The levels of 0-lymphocytes and CIC were on the increase. Salmonellosis of long duration was characterized by hyperactivity of autoimmune reactions.
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PMID:[Immunologic status of patients with Salmonella infections]. 269 21

Thirty silent lupus nephritis (SLN) patients were compared to 16 individuals bearing overt lupus nephritis (OLN). Results included: years of systemic lupus erythematosus (SLE) diagnosis were significantly earlier (4.6 +/- 2.8 years) in SLN than in OLN (7.18 +/- 3.61) (P < 0.05). Neurological compromise, hypertension, normocitic anemia and lymphopenia were significantly prevalent in OLN than in SLN (P < 0.05). Beside normal urinary sediment and renal function tests, the SLN group showed a moderate increase of both activity (AI) and chronicity (CI) renal pathology index when compared to highly increased AI and CI in OLN (P < 0.05). Seventy percent of SLN patients were ISN/RPS Classes I (6.6%) and II (63.3%) while 81% of OLN cases were Classes III, IV (37.5%) and V. IgG, IgA, IgM, lambda chain, C3 and fibrinogen immune deposits were found in 90% or over in both SLN and OLN individuals while in 60% or over, both groups also showed kappa chain, Clq and C4 deposits. While prevalence of ANA, anti-dsDNA and anti-C1q antibodies were similar in both groups, anti-histone, anti-RNP, CIC and CH50 serum levels were significantly different in OLN versus SLN (P < 0.05). We strongly suggest that indeed SLN is the earliest stage in the natural history of lupus nephritis.
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PMID:Further description of early clinically silent lupus nephritis. 1721 89