Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024312 (
lymphopenia
)
4,859
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Radiotherapy induces
galectin-1
(Gal-1) secretion by tumors, which induces CD8(+) T-cell apoptosis and
lymphopenia
. These effects are substantially decreased by Gal-1 shRNA. Inhibition of Gal-1 may be an effective strategy for overcoming radiation-induced
lymphopenia
, which may improve clinical outcomes.
...
PMID:Galectin-1 and immune suppression during radiotherapy. 2518 84
