Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0024312 (lymphopenia)
 4,859 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Studied were 7 clinically normal sheep chosen randomly (merino, Tsigai, and crosses of these as well as Stara Zagora breed and merino crosses), aged 2-3 years, at an average weight of 52.71 kg. I/v neuroleptanalgesia was carried out (with no surgery to follow) at preliminary premedication with atropini sulfas at 350 Y/kg M., in s/c application, and a mixture of Droperidol at 0.25 mg/kg M. and Fentanyl at 0.005 mg/kg M. in i/m application. Fifteen min later the basic portion of the Droperidol (0.25 mg/kg) and Fentanyl (0.010 mg/kg) mixture was introduced (i/v). The changes in the blood were followed up prior to and after anaesthesia at the 1st, 3rd, and 24th hour and on the 4th and 7th day with regard to hemoglobin, erythrocytes, erythrocyte sedimentation rate, hematocrit, leukocytes and leukocyte formula, total protein and protein fractions, Ca, P, Mg, Na, K, total and direct bilirubin, and fibrinogen. It was found that hemoglobin and erythrocyte values were close to the normal ones. The higher leukocyte count at the 3rd and 24th hour following neuroleptanalgesia was accompanied by transient moderate neutrophilia, lymphopenia, and very slight eosinopenia. The total protein, protein fractions, fibrinogen, total and direct bilirubin, Ca, Na, and K did not show essential changes. Phosphorus and Mg dropped at the 3rd and 24th hour, and on the 7th day did not come back to normal.
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PMID:[Hematological changes in sheep during neuroleptanalgesia with droperidol and fentanyl]. 376 84

Intravenous potentiated anesthesia was made with six clinically normal boars of the White Bulgarian breed, weighing 50 kg, premedication of Atropini sulfas (50 gamma/kg M., s/c) and of a mixture of Droperidol (0.25 mg/kg M.) and Fentanyl (0.05 mg/kg M.) introduced via Sinus venosus ophthalmicus being administered 15 min. prior to 13 mg/kg M. of 5% water solution of thiopental-sodium injected in the same sinus. Prior to and following anesthesia at the 1st, 3rd, and 24th hour and on the 4th and 7th day the blood was checked with regard to hemoglobin, erythrocytes, erythrocyte sedimentation rate, hematocrit, leukocytes and leukocyte formula, total protein and protein fractions, calcium, phosphorus, magnesium, sodium, potassium, chlorides, total and direct bilirubin, and fibrinogen. Hemoglobin, erythrocytes, and hematocrit were found to drop insignificantly mathematically. The rate of increase of the sedimentation did not fully correspond to the drop of the erythrocyte count. The increase in leukocytes was accompanied by transient neutrophilia, eosinopenia, and lymphopenia in the early hours following anesthesia. The changes in the total protein and protein fractions, fibrinogen, total and direct bilirubin, and the other element indices referred to were shown to be close to the physiologic levels.
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PMID:[Hematologic and biochemical changes in the blood of boars undergoing potentiated anesthesia with droperidol, fentanyl and thiopental]. 378 57