Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024312 (
lymphopenia
)
4,859
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The specific features of immunological responsiveness were studied in 124 Mycobacterium tuberculosis (MBT)-infected children aged 7-14 years in relation to the ecological characteristics of their living area. All the children had early primary tuberculosis infection. The MBT-infected children were found to have first-degree secondary immunodeficiency. The latter was most pronounced in the dwellers of industrial areas, who had T-lymphocytic deficiency, the impaired supopulational composition of T cells, their diminished functional activity, an increased response to specific antigen, as well as dysimmunoglobulinemia, elevated levels of circulating immune complexes. The hyposuppressor types of cellular immunodeficiency and total T
lymphopenia
were observed in children living in the ecological crisis area.
Superinfection
and concomitant diseases create conditions for the progression of secondary immunodeficiency and for the development of severe forms of the disease.
...
PMID:[Influence of environmental factors on the immunological responsiveness of Mycobacterium tuberculosis-infected children]. 1627 13
