Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024141 (systemic lupus erythematosus)
 44,322 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FAM167B 9.5
CXorf21 9.5
sentrin/SUMO-specific protease 7 9.5
INTERFERON REGULATORY FACTOR 3 9.5
Sm D2 9.5
PCNXL3 9.5
SLED1 9.5
DNAPTP6 9.5
LOC63920 9.5
complement component 1, q subcomponent, B chain 9.5
TMEM203 9.5
RNF15 9.5
limb bud and heart development homolog 9.5
ankyrin repeat domain 44 9.5
testis specific, 10 9.5
ANKRD50 9.5
P450-CYP21B 9.5
FAM71E1 9.5
IGHV3-43 9.5
zinc finger protein 688 9.5
CREBL1 9.5
WDFY family member 4 9.5
solute carrier family 15, member 4 8.9
UHRF1BP1 8.9
LRRC18 8.9
TROVE2 8.6
WDFY4 8.6
B-cell scaffold protein with ankyrin repeats 8.5
AF4/FMR2 family, member 1 8.5
WFDC3 8.5
U2 snRNP-A' 8.5
USP41 8.5
FcGR 8.5
TROVE domain family, member 2 8.5
complement component 1, q subcomponent, A chain 8.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 8.5
C10orf64 8.5
Sm D3 8.5
FAM72C 8.5
CD159c 8.5
DNASE1L3 8.4
beta2-glycoprotein I 8.3
KIAA1542 8.2
LBA1 8.2
U1-70K 8.1
SS-A 8.1
SS-B 8.0
DNASE1 7.9
BANK1 7.9
SS-B/La protein 7.9
RNF18 7.9
platelet receptor for type III collagen 7.9
OR8D4 7.9
Complement component 2 7.9
RAVER2 7.9
PXK 7.9
STRBP 7.9
C3orf67 7.9
protein kinase C, delta 7.9
EP2 prostaglandin receptor 7.9
PTP-HSCF 7.9
Syntaxin-1B 7.9
superkiller viralicidic activity 2-like 7.9
beta4Gal-T4 7.9
UNC93B1 protein 7.9
Leukocyte immunoglobulin-like receptor A3 7.9
MAMDC1 7.9
TREX1 7.9
FCGR2B 7.8
ITGAM 7.8
SSA 7.8
Transmembrane protein 39A 7.8
TNFSF7 7.7
DEF6 7.7
PROZ 7.7
XKR6 7.7
SLC15A4 7.7
Ro60 7.6
ribonuclease H2 7.6
Ro52 7.6
more...
Disease
Acute arthropathy 9.5
Type I hyperlipidemia 9.5
Peritoneal vasculitis 9.5
Acute systemic lupus erythematosus 9.5
Systemic connective tissue disorders 9.5
Congenital vascular disease 9.5
LP-LE overlap 9.5
Chronic adhesive pericarditis 9.5
SLE with pericarditis 9.5
Malignancy-associated glomerulonephritis 9.5
Lupus pneumonitis 9.5
SLE inhibitor 9.5
SLE arthritis 9.5
AIDS with thrombocytopenia 9.5
Streptococcus pyogenes cellulitis 9.5
Acquired hypoprothrombinemia 9.5
Sjogren's syndrome, secondary 9.5
Chronic proliferative glomerulonephritis 9.5
Streptococcal cellulitis 9.5
SLE with diffuse proliferative glomerulonephritis 9.5
Trichophytic granuloma 9.5
Rheumatic pneumonia 9.5
thrombosis; pregnancy 9.5
Acute subendocardial infarction 9.5
Autoimmune leukopenia 9.5
Central Nervous System Lupus 9.5
SLE flare 9.5
Pulmonary alveolar hemorrhage 9.5
SLEB2 9.5
Lupus myocarditis 9.5
systemic lupus erythematosus 9.5
syndrome; cervical 9.5
SLE with normal kidneys 9.5
Lupus hepatitis 9.5
Acute cutaneous lupus erythematosus 9.5
Lupus 9.5
Bullous systemic lupus erythematosus 9.4
lupus 9.4
lupus 9.4
SLE 9.3
Lupus-like syndrome 9.3
Neuropsychiatric lupus 9.2
Libman-Sacks endocarditis 9.2
Lupus erythematosus profundus 9.1
Secondary antiphospholipid syndrome 9.1
Cerebral lupus 9.1
drug induced lupus 9.0
lupus nephritis 8.9
SLEH1 8.9
Jaccoud 8.8
Cutaneous lupus erythematosus 8.8
Neonatal lupus erythematosus 8.7
Hughes syndrome 8.7
Rowell's syndrome 8.6
mixed connective tissue disease 8.6
antiphospholipid syndrome 8.5
Subacute cutaneous lupus erythematosus 8.5
Jadassohn-Pellizzari 8.5
Other skin disorders 8.5
Pavingstone degeneration 8.5
Carcinomatosis peritonei 8.5
lupus vulgaris tuberculosis 8.5
Facial psoriasis 8.5
Staphylococcus aureus cellulitis 8.5
Purpura hemorrhagica 8.5
Lupus vasculitis 8.5
Oral papillomatosis 8.5
megalerythema 8.5
infected insect bite 8.5
Folie a trois 8.5
Drug-induced erythroderma 8.5
Noninfective endocarditis 8.5
Bacillus infection 8.5
SLE encephalopathy 8.5
Purpura hemorrhagica 8.5
Primary antiphospholipid syndrome 8.4
Chronic interstitial cystitis 8.3
Congenital heart block 8.2
C1q nephropathy 8.2
Lupus erythematosus tumidus 8.2
more...
Symptom
Red face 9.5
generalized skin papules 9.5
SLE-like symptoms 9.3
Ballismus 8.5
Urticarial vasculitis 7.8
livedo 7.4
Auspitz's sign 7.2
skin impairment 7.0
Diaphragmatic weakness 6.8
respiratory pain 6.7
Axillary lymphadenopathy 6.7
Flare 6.4
Acute back pain 6.3
decreased bowel sounds 6.0
Night pain 5.9
Livedoid 5.8
polymyalgia 5.8
Pitting edema 5.8
chorea 5.7
Cognitive Symptoms 5.7
Murphy's sign 5.6
KIDNEY 5.5
arthralgia 5.3
waxy flexibility 5.2
periorbital edema 5.2
Koplik spots 5.2
Cutaneous anergy 5.2
toe pain 5.0
vaginal discomfort 5.0
pleuritic chest pain 5.0
gumma 5.0
Skin symptoms 5.0
sialectasis 5.0
Cushingoid 4.9
Cushingoid 4.8
change in skin color 4.8
Osler's nodes 4.8
Beau's lines 4.8
Breathiness 4.5
abdominal rigidity 4.5
Musculoskeletal symptoms 4.4
orthopnea 4.3
pedal edema 4.3
Kayser-Fleischer ring 4.3
splenomegaly 4.0
swollen joints 4.0
fever of unknown origin 4.0
feeling depressed 4.0
vaginal pain 3.9
erythema 3.9
Gastrointestinal symptoms 3.9
Darier's sign 3.9
growing pains 3.9
generalized pain 3.9
Amaurosis fugax 3.8
mirror writing 3.8
koilonychia 3.8
myalgia 3.8
night sweats 3.8
Psychiatric symptoms 3.7
thoracic back pain 3.7
catatonia 3.7
abnormal reflex 3.7
leg edema 3.7
Visual disturbances 3.7
General symptoms 3.6
generalized erythema 3.6
Neurologic symptoms 3.6
hepatosplenomegaly 3.5
consciousness disturbance 3.5
dry eye 3.5
intestinal angina 3.4
acute abdominal pain 3.4
tonic-clonic seizure 3.3
hypoproteinemia 3.1
acute abdomen 3.1
stuffy nose 3.1
scaly skin 3.1
onychomadesis 3.0
asthenia 3.0
more...
Drug
Edratide 9.5
Belimumab 9.2
Anadrol-50 8.5
Methylprednisolone suleptanate 8.5
Epratuzumab 8.4
Frentizole 8.1
Abetimus sodium 8.1
BLyS 7.8
Plaquenil 7.1
Plaquenil 7.1
Methotrexate sodium 6.7
Gadofosveset trisodium 6.5
Lobenzarit disodium 6.5
Thalomid 6.3
Emivirine 6.2
Dexamethasone palmitate 6.2
Cadralazine 6.0
Kaolin 6.0
Loxoribine 5.9
BZQ 5.7
Roquinimex 5.6
Abatacept 5.6
Agalsidase alfa 5.5
Cellcept 5.5
Cellcept 5.5
Pronestyl 5.4
Calamine 5.4
Rituximab 5.3
Ancrod 5.2
Ocrelizumab 5.1
Foscavir 5.0
Bindarit 5.0
Opana 5.0
Methylprednisolone 4.9
Iguratimod 4.8
Calciparine 4.8
Ticlopidine hydrochloride 4.8
Clinoril 4.8
Prednisone 4.8
Satraplatin 4.7
Prednisolone 4.7
Tocilizumab 4.6
Sulphasalazine 4.6
Cod liver oil 4.5
Mestinon 4.5
Mizoribine 4.5
Thioguanine 4.4
Imuran 4.4
Interferon beta-1a 4.4
Palonosetron hydrochloride 4.4
Minipress 4.4
Mycophenolic acid 4.4
Fosamax 4.3
Infliximab 4.3
Infliximab 4.3
Eculizumab 4.2
Golimumab 4.2
Interferon alfa-2a 4.1
Anakinra 4.1
Deflazacort 4.1
Stannous chloride 4.1
Cilastatin 4.0
Adalimumab 4.0
Omacor 4.0
Aredia 3.9
Quinine, 3.8
CS-514 3.8
Potassium citrate 3.8
Hirulog 3.7
Isoprinosine 3.7
Romidepsin 3.7
Certolizumab pegol 3.6
Atabrine 3.6
Synercid 3.6
LVFX 3.6
Batroxobin 3.5
Beraprost sodium 3.5
Gamma globulin 3.4
Estrogens 3.4
Marimastat 3.3
more...
Enzyme
yeast ribonuclease 7.9
EC 3.1.1.48 7.9
GP-I 7.2
BAST 6.3
coagulation factor IXa 5.3
peptidylarginine deiminase 5.2
dihydrolipoyl transacylase 5.2
thromboplastin 5.0
proteinase-3 4.9
ancrod 4.8
D-dopachrome tautomerase 4.5
C3b inactivator 4.5
C3 convertase 4.4
APC 4.3
factor D 4.3
histidyl-tRNA synthetase 4.2
coagulation factor XIa 4.2
galactosylhydroxylysyl glucosyltransferase 4.1
PHOSPHO1 4.0
C3 convertase 4.0
p80 4.0
DNase 3.7
LGT 3.6
DNase II 3.6
methylenetetrahydrofolate reductase 3.5
methylenetetrahydrofolate reductase 3.5
histone-lysine N-methyltransferase 3.5
C1 esterase 3.4
thiopurine methyltransferase 3.4
p100 3.4
deoxyribonuclease 3.3
deoxyribonuclease 3.2
eEF2 kinase 3.2
dihydroxyacetone phosphate acyltransferase 3.1
PHT 3.1
inositol phosphatase 3.1
asparaginyl-tRNA synthetase 3.0
pyruvate dehydrogenase phosphatase 3.0
CDR 2.9
mannosidase II 2.9
thyroid peroxidase 2.9
prolidase 2.9
paraoxonase 2.8
CEP 2.7
alanyl-tRNA synthetase 2.7
ceramide kinase 2.7
DAP II 2.7
bromelin 2.7
LMT 2.7
IMP dehydrogenase 2.7
GTI 2.6
versatile peroxidase 2.6
TSP-1 2.6
carnosinase 2.5
glycoprotease 2.5
thrombin-activatable fibrinolysis inhibitor 2.5
MCS 2.5
GLO 2.4
granzyme B 2.4
formyltetrahydrofolate synthetase 2.3
E-2 2.3
paraoxonase 2.3
methylenetetrahydrofolate dehydrogenase 2.3
SLB 2.3
lipoate acetyltransferase 2.3
Thy1 2.2
thrombin 2.2
inosine triphosphatase 2.2
CEP 2.2
oxoglutarate dehydrogenase 2.2
alpha-N-acetylgalactosaminidase 2.2
tissue plasminogen activator 2.1
21-hydroxylase 2.1
Hageman factor 2.1
bromelain 2.1
TRS 2.1
arginine deiminase 2.1
caspase-11 2.0
caspase-11 2.0
anthranilate synthase 2.0
more...
Compound
Armepavine 8.5
Hydroxychloroquine 7.8
Pristane 7.6
Iminostilbene 7.5
Hydroxychloroquine sulfate 7.3
2-azaspiro[4.5]decane 6.9
4-(2-Hydroxyethyl)piperazine 6.9
4-(2-Hydroxyethyl)piperazine 6.9
Conformer B 6.9
Mycophenolate mofetil 6.5
Ethylestrenol 6.5
T 41 6.3
ANA 6.2
Procainamide 6.2
ANA 6.2
Triamcinolone hexacetonide 6.2
Sinomenine hydrochloride 6.2
ANCA 6.0
16 alpha-hydroxyestrone 5.9
Glycylproline 5.9
APS 5.7
Tylophorine 5.6
Hydralazine 5.6
DNPP 5.4
NHD 5.4
Complement factor B 5.3
1-heptyne 5.3
238A 5.2
Interferon alfa-2a 5.1
DQ1 5.1
TNX 5.1
Prospidin 5.0
DFH 5.0
Leflunomide 5.0
Methylprednisolone 4.9
Azathioprine 4.9
PAPS 4.9
GAH 4.9
Tanakan 4.8
Nandrolone decanoate 4.8
Prednisolone 4.7
Aminoimidazole 4.7
T undecanoate 4.7
Acar 4.6
AFMU 4.5
Acebutolol 4.5
CCP 4.5
Minipress 4.4
Infecundin 4.4
S 9 4.4
Tuberculostearic acid 4.4
Canavanine 4.3
Minocycline hydrochloride 4.3
Danazol 4.3
11-dehydro-thromboxane 4.2
Salvarsan 4.2
Factor H 4.2
Tuftsin 4.2
Prednisone 4.1
AS-101 4.1
TMPD 4.1
Nickel chloride 4.1
Cilastatin 4.0
Poly C 4.0
Etanercept 4.0
Deoxyspergualin 4.0
ITP 4.0
Tocainide 3.9
Mephenytoin 3.9
Nafoxidine 3.9
cycloheptane 3.9
Paeoniflorin 3.9
Daphnetin 3.8
8-hydroxyguanosine 3.8
Chloroquine 3.8
Minocycline 3.8
Chloroquine 3.8
Solu-Medrol 3.8
Practolol 3.8
HAQ 3.7
more...