Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0024141 (systemic lupus erythematosus)
44,322 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 2636
cytokine 1462
She 1234
Mol 926
CD4 905
interferon 740
IgA 728
IFN 721
glycoprotein 714
collagen 678
prothrombin 605
HLA 591
IL-6 578
lymphoid 576
thromboplastin 558
TNF 554
SSA 543
RNP 508
rheumatoid factor 500
autoantigen 488
histone 475
IL-10 466
ANA 438
CD8 397
ankylosing spondylitis 396
Fas 393
C-reactive protein 374
tumor necrosis factor 372
thymus 367
beta2-glycoprotein I 355
SSB 354
protein C 328
IL-2 316
SS-A 295
ACR 292
protein S 288
insulin 287
BAFF 271
IFN-gamma 266
MRI 266
IL-17 264
ribonucleoprotein 262
IL-4 261
TLR7 252
TLR9 236
CD20 233
type I interferon 232
thrombin 224
MHC 223
TNF-alpha 222
SS-B 222
albumin 221
serum albumin 213
major histocompatibility complex 213
fibrinogen 199
lipopolysaccharide 197
B lymphocyte stimulator 194
IgG3 190
TCR 179
chemokine 175
dilute 172
CD25 170
polypeptide 167
myeloperoxidase 165
factor VIII 163
CD40 162
T cell receptor 157
LPS 157
IL-1 156
GPI 155
APS 155
prolactin 152
interleukin-6 152
ESR 152
HLA-DR 150
Pol 148
CD40L 148
factor V Leiden 147
Cytokine 142
DR3 142
more...
Disease
systemic lupus erythematosus 44322
lupus 20554
lupus 14981
Lupus 6889
rheumatoid arthritis 5290
autoimmune disease 4502
SLE 4409
lupus nephritis 3143
antiphospholipid syndrome 2503
arthritis 2430
vasculitis 2120
glomerulonephritis 1852
proteinuria 1567
renal disease 1546
PSS 1500
thrombocytopenia 1434
nephritis 1379
cancer 1284
hypertension 1085
multiple sclerosis 1079
diabetes 917
scleroderma 875
rash 834
dermatomyositis 796
atherosclerosis 790
mixed connective tissue disease 714
connective tissue disease 636
psoriasis 598
renal failure 563
nephrotic syndrome 556
polymyositis 549
anemia 525
lymphadenopathy 507
tuberculosis 503
stroke 497
tumor 478
lymphoma 415
HIV 414
ankylosing spondylitis 411
Sjogren's syndrome 404
infectious diseases 387
Raynaud's phenomenon 386
cardiovascular disease 386
type 1 diabetes 384
hemolytic anemia 384
pneumonia 381
hepatitis 381
abortion 373
depression 365
Crohn's disease 359
immunodeficiency 359
sarcoidosis 343
photosensitivity 338
inflammatory bowel disease 332
preeclampsia 315
sepsis 306
systemic disease 305
thrombocytopenic purpura 303
Wegener's granulomatosis 301
pulmonary hypertension 301
leukopenia 289
Epstein 284
heart block 282
myasthenia gravis 279
membranous nephropathy 274
osteoarthritis 273
pericarditis 272
psoriatic arthritis 266
sepsis 264
myocardial infarction 264
asthma 258
deep vein thrombosis 253
myositis 249
syphilis 247
psychosis 245
skin disease 240
virus infection 239
rheumatism 237
plaque 235
purpura 234
more...
Symptom
pain 452
arthralgia 399
seizures 384
headache 381
fatigue 360
abdominal pain 279
erythema 277
dyspnea 249
weakness 230
splenomegaly 226
livedo 198
diarrhea 166
vomiting 152
chorea 152
myalgia 129
nausea 117
chest pain 112
cough 101
Ill 82
hepatosplenomegaly 71
hemoptysis 66
collapse 61
angina 60
shortness of breath 59
respiratory distress 58
regurgitation 58
fever of unknown origin 46
anesthesia 44
hepatomegaly 41
dry eye 41
anorexia 40
back pain 39
numbness 39
ataxia 38
exertional dyspnea 37
acute abdomen 37
dizziness 35
asthenia 30
chills 30
acute abdominal pain 29
vertigo 29
paraparesis 27
hemiplegia 27
pleuritic chest pain 26
paresis 26
paresthesia 26
discomfort 24
cerebellar ataxia 24
low back pain 24
night sweats 23
blurred vision 23
dysarthria 23
discomfort 22
sleepiness 22
epigastric pain 22
thinning 21
Flare 21
hoarseness 21
exhaustion 20
catatonia 20
insomnia 19
lethargy 19
pallor 18
tonic-clonic seizure 18
tense 17
syncope 17
nausea and vomiting 17
tremor 17
overweight 17
cachexia 17
dysuria 16
memory loss 16
sore throat 15
oliguria 15
constipation 14
spasm 14
Urticarial vasculitis 14
hypoproteinemia 14
orthopnea 13
cyanosis 13
more...
Drug
Dermatol 1248
IL-2 317
IFN-gamma 257
Rituximab 155
CSF 128
CTX 108
Cardiovasc 99
Nephron 90
lysine 81
Dial 81
Belimumab 80
Nephron 70
BLyS 65
DNase I 57
Prednisolone 54
ROC 51
Prednisone 39
Methylprednisolone 37
Asthma 36
Estrogens 32
Infliximab 31
Infliximab 31
ROS 30
Gel 28
Monit 26
Tacrolimus 23
MAP 22
IFN-beta 21
Kaolin 21
EE2 19
G-CSF 18
Epratuzumab 18
ampicillin 17
p75 16
ENT 15
vitamin E 15
Fluorescein 14
Fluorescein 14
Tocilizumab 14
Abatacept 13
Isoniazid 13
ABC 13
CTX 13
CTX 13
Silica 12
Adalimumab 12
Alliance 11
IL-1ra 11
Bortezomib 11
ascorbate 11
TAT 10
Nitric Oxide 10
Mycophenolic acid 10
Vitamin B12 9
Albumin 9
nitroglycerin 9
Eculizumab 9
Leaf 9
Serum albumin 9
EPA 9
Bifidobacterium 9
Plaquenil 8
Plaquenil 8
THF 8
Captopril 8
Dakar 8
Asn 8
PCB 7
Lovastatin 7
Indomethacin 7
Vitamin K 7
CAM 6
Fragment 6
ETS 6
Anakinra 6
LMWH 6
CCL 6
Biopolymers 6
BLM 6
NAG 6
more...
Enzyme
thromboplastin 596
APC 452
peroxidase 235
thrombin 217
mitogen-activated protein kinase 153
DNase 141
focal adhesion kinase 134
ERK 117
RNase 92
RNase 84
RNA polymerase 79
calcineurin 78
protein kinase 74
alkaline phosphatase 71
tissue plasminogen activator 68
proteasome 61
trypsin 60
superoxide dismutase 53
renin 53
reverse transcriptase 47
caspase-3 46
alanine aminotransferase 46
catalase 46
luciferase 44
ACE 43
creatine kinase 43
protein kinase C 41
lactate dehydrogenase 37
methylenetetrahydrofolate reductase 34
methylenetetrahydrofolate reductase 34
thyroid peroxidase 32
endonuclease 32
aspartate aminotransferase 32
C3 convertase 31
lysozyme 31
caspase-1 30
plasmin 28
elastase 28
ribonuclease 27
ribonuclease 27
CDR 26
urokinase-type plasminogen activator 26
glutathione peroxidase 25
DNA methyltransferase 25
NADPH oxidase 25
pepsin 25
NADPH oxidase 25
kallikrein 25
ATPase 24
neuraminidase 24
granzyme B 24
IKK 22
collagenase 22
C3 convertase 21
lipase 21
deoxyribonuclease 20
deoxyribonuclease 20
glutathione S-transferase 19
transglutaminase 18
phospholipase A2 18
PARP 18
peptidylarginine deiminase 18
topoisomerase 18
transcriptase 18
ceruloplasmin 18
P-glycoprotein 17
DNA polymerase 17
topoisomerase 17
AST 16
paraoxonase 16
enolase 16
S1 nuclease 16
gamma-glutamyl transpeptidase 16
MEK 15
caspase-8 15
beta-galactosidase 15
AMP-activated protein kinase 14
MAP 14
ACS 14
CAD 14
more...
Compound
Clin 6088
DNA 5315
Dec 2925
creatinine 598
TNF 554
ANA 440
ANA 440
calcium 389
oxygen 297
vitamin D 194
sulfate 192
Cardiol 191
arginine 177
water 174
sodium 173
phosphate 169
ANCA 166
glucose 160
His 159
acetate 157
tyrosine 157
APS 155
Hydroxychloroquine 144
urea 142
nitrogen 131
PEG 126
CTX 108
serine 103
lysine 102
nitric oxide 101
BCR 98
DBA 97
DBA 97
DBA 97
salt 93
SDS 84
homocysteine 82
Dial 81
iron 81
Mycophenolate mofetil 75
leucine 72
prostacyclin 69
ATP 69
potassium 69
hydrogen 62
EDTA 61
Estrogen 61
EDTA 61
ADP 56
zinc 53
Vitamin D 53
Prednisolone 53
ammonium 52
PEG 51
CCP 50
CO2 50
Asp 49
Estrogen 49
A 42 49
Cyclosporine 48
threonine 47
iodine 46
PMA 45
Pac 45
ITP 44
Optimal 44
tryptophan 43
Azathioprine 43
ADP 42
alanine 42
ADP 42
mercury 41
Phe 41
PMA 41
tryptophan 40
tryptophan 40
Pristane 40
ASA 40
tryptophan 40
Hydralazine 40
more...