Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0024141 (
systemic lupus erythematosus
)
44,322
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
2636
cytokine
1462
She
1234
Mol
926
CD4
905
interferon
740
IgA
728
IFN
721
glycoprotein
714
collagen
678
prothrombin
605
HLA
591
IL-6
578
lymphoid
576
thromboplastin
558
TNF
554
SSA
543
RNP
508
rheumatoid factor
500
autoantigen
488
histone
475
IL-10
466
ANA
438
CD8
397
ankylosing spondylitis
396
Fas
393
C-reactive protein
374
tumor necrosis factor
372
thymus
367
beta2-glycoprotein I
355
SSB
354
protein C
328
IL-2
316
SS-A
295
ACR
292
protein S
288
insulin
287
BAFF
271
IFN-gamma
266
MRI
266
IL-17
264
ribonucleoprotein
262
IL-4
261
TLR7
252
TLR9
236
CD20
233
type I interferon
232
thrombin
224
MHC
223
TNF-alpha
222
SS-B
222
albumin
221
serum albumin
213
major histocompatibility complex
213
fibrinogen
199
lipopolysaccharide
197
B lymphocyte stimulator
194
IgG3
190
TCR
179
chemokine
175
dilute
172
CD25
170
polypeptide
167
myeloperoxidase
165
factor VIII
163
CD40
162
T cell receptor
157
LPS
157
IL-1
156
GPI
155
APS
155
prolactin
152
interleukin-6
152
ESR
152
HLA-DR
150
Pol
148
CD40L
148
factor V Leiden
147
Cytokine
142
DR3
142
more...
Disease
systemic lupus erythematosus
44322
lupus
20554
lupus
14981
Lupus
6889
rheumatoid arthritis
5290
autoimmune disease
4502
SLE
4409
lupus nephritis
3143
antiphospholipid syndrome
2503
arthritis
2430
vasculitis
2120
glomerulonephritis
1852
proteinuria
1567
renal disease
1546
PSS
1500
thrombocytopenia
1434
nephritis
1379
cancer
1284
hypertension
1085
multiple sclerosis
1079
diabetes
917
scleroderma
875
rash
834
dermatomyositis
796
atherosclerosis
790
mixed connective tissue disease
714
connective tissue disease
636
psoriasis
598
renal failure
563
nephrotic syndrome
556
polymyositis
549
anemia
525
lymphadenopathy
507
tuberculosis
503
stroke
497
tumor
478
lymphoma
415
HIV
414
ankylosing spondylitis
411
Sjogren's syndrome
404
infectious diseases
387
Raynaud's phenomenon
386
cardiovascular disease
386
type 1 diabetes
384
hemolytic anemia
384
pneumonia
381
hepatitis
381
abortion
373
depression
365
Crohn's disease
359
immunodeficiency
359
sarcoidosis
343
photosensitivity
338
inflammatory bowel disease
332
preeclampsia
315
sepsis
306
systemic disease
305
thrombocytopenic purpura
303
Wegener's granulomatosis
301
pulmonary hypertension
301
leukopenia
289
Epstein
284
heart block
282
myasthenia gravis
279
membranous nephropathy
274
osteoarthritis
273
pericarditis
272
psoriatic arthritis
266
sepsis
264
myocardial infarction
264
asthma
258
deep vein thrombosis
253
myositis
249
syphilis
247
psychosis
245
skin disease
240
virus infection
239
rheumatism
237
plaque
235
purpura
234
more...
Symptom
pain
452
arthralgia
399
seizures
384
headache
381
fatigue
360
abdominal pain
279
erythema
277
dyspnea
249
weakness
230
splenomegaly
226
livedo
198
diarrhea
166
vomiting
152
chorea
152
myalgia
129
nausea
117
chest pain
112
cough
101
Ill
82
hepatosplenomegaly
71
hemoptysis
66
collapse
61
angina
60
shortness of breath
59
respiratory distress
58
regurgitation
58
fever of unknown origin
46
anesthesia
44
hepatomegaly
41
dry eye
41
anorexia
40
back pain
39
numbness
39
ataxia
38
exertional dyspnea
37
acute abdomen
37
dizziness
35
asthenia
30
chills
30
acute abdominal pain
29
vertigo
29
paraparesis
27
hemiplegia
27
pleuritic chest pain
26
paresis
26
paresthesia
26
discomfort
24
cerebellar ataxia
24
low back pain
24
night sweats
23
blurred vision
23
dysarthria
23
discomfort
22
sleepiness
22
epigastric pain
22
thinning
21
Flare
21
hoarseness
21
exhaustion
20
catatonia
20
insomnia
19
lethargy
19
pallor
18
tonic-clonic seizure
18
tense
17
syncope
17
nausea and vomiting
17
tremor
17
overweight
17
cachexia
17
dysuria
16
memory loss
16
sore throat
15
oliguria
15
constipation
14
spasm
14
Urticarial vasculitis
14
hypoproteinemia
14
orthopnea
13
cyanosis
13
more...
Drug
Dermatol
1248
IL-2
317
IFN-gamma
257
Rituximab
155
CSF
128
CTX
108
Cardiovasc
99
Nephron
90
lysine
81
Dial
81
Belimumab
80
Nephron
70
BLyS
65
DNase I
57
Prednisolone
54
ROC
51
Prednisone
39
Methylprednisolone
37
Asthma
36
Estrogens
32
Infliximab
31
Infliximab
31
ROS
30
Gel
28
Monit
26
Tacrolimus
23
MAP
22
IFN-beta
21
Kaolin
21
EE2
19
G-CSF
18
Epratuzumab
18
ampicillin
17
p75
16
ENT
15
vitamin E
15
Fluorescein
14
Fluorescein
14
Tocilizumab
14
Abatacept
13
Isoniazid
13
ABC
13
CTX
13
CTX
13
Silica
12
Adalimumab
12
Alliance
11
IL-1ra
11
Bortezomib
11
ascorbate
11
TAT
10
Nitric Oxide
10
Mycophenolic acid
10
Vitamin B12
9
Albumin
9
nitroglycerin
9
Eculizumab
9
Leaf
9
Serum albumin
9
EPA
9
Bifidobacterium
9
Plaquenil
8
Plaquenil
8
THF
8
Captopril
8
Dakar
8
Asn
8
PCB
7
Lovastatin
7
Indomethacin
7
Vitamin K
7
CAM
6
Fragment
6
ETS
6
Anakinra
6
LMWH
6
CCL
6
Biopolymers
6
BLM
6
NAG
6
more...
Enzyme
thromboplastin
596
APC
452
peroxidase
235
thrombin
217
mitogen-activated protein kinase
153
DNase
141
focal adhesion kinase
134
ERK
117
RNase
92
RNase
84
RNA polymerase
79
calcineurin
78
protein kinase
74
alkaline phosphatase
71
tissue plasminogen activator
68
proteasome
61
trypsin
60
superoxide dismutase
53
renin
53
reverse transcriptase
47
caspase-3
46
alanine aminotransferase
46
catalase
46
luciferase
44
ACE
43
creatine kinase
43
protein kinase C
41
lactate dehydrogenase
37
methylenetetrahydrofolate reductase
34
methylenetetrahydrofolate reductase
34
thyroid peroxidase
32
endonuclease
32
aspartate aminotransferase
32
C3 convertase
31
lysozyme
31
caspase-1
30
plasmin
28
elastase
28
ribonuclease
27
ribonuclease
27
CDR
26
urokinase-type plasminogen activator
26
glutathione peroxidase
25
DNA methyltransferase
25
NADPH oxidase
25
pepsin
25
NADPH oxidase
25
kallikrein
25
ATPase
24
neuraminidase
24
granzyme B
24
IKK
22
collagenase
22
C3 convertase
21
lipase
21
deoxyribonuclease
20
deoxyribonuclease
20
glutathione S-transferase
19
transglutaminase
18
phospholipase A2
18
PARP
18
peptidylarginine deiminase
18
topoisomerase
18
transcriptase
18
ceruloplasmin
18
P-glycoprotein
17
DNA polymerase
17
topoisomerase
17
AST
16
paraoxonase
16
enolase
16
S1 nuclease
16
gamma-glutamyl transpeptidase
16
MEK
15
caspase-8
15
beta-galactosidase
15
AMP-activated protein kinase
14
MAP
14
ACS
14
CAD
14
more...
Compound
Clin
6088
DNA
5315
Dec
2925
creatinine
598
TNF
554
ANA
440
ANA
440
calcium
389
oxygen
297
vitamin D
194
sulfate
192
Cardiol
191
arginine
177
water
174
sodium
173
phosphate
169
ANCA
166
glucose
160
His
159
acetate
157
tyrosine
157
APS
155
Hydroxychloroquine
144
urea
142
nitrogen
131
PEG
126
CTX
108
serine
103
lysine
102
nitric oxide
101
BCR
98
DBA
97
DBA
97
DBA
97
salt
93
SDS
84
homocysteine
82
Dial
81
iron
81
Mycophenolate mofetil
75
leucine
72
prostacyclin
69
ATP
69
potassium
69
hydrogen
62
EDTA
61
Estrogen
61
EDTA
61
ADP
56
zinc
53
Vitamin D
53
Prednisolone
53
ammonium
52
PEG
51
CCP
50
CO2
50
Asp
49
Estrogen
49
A 42
49
Cyclosporine
48
threonine
47
iodine
46
PMA
45
Pac
45
ITP
44
Optimal
44
tryptophan
43
Azathioprine
43
ADP
42
alanine
42
ADP
42
mercury
41
Phe
41
PMA
41
tryptophan
40
tryptophan
40
Pristane
40
ASA
40
tryptophan
40
Hydralazine
40
more...